{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T17:28:02Z","timestamp":1790184482943,"version":"4.1.0"},"reference-count":37,"publisher":"Institution of Engineering and Technology (IET)","issue":"2","license":[{"start":{"date-parts":[[2016,7,1]],"date-time":"2016-07-01T00:00:00Z","timestamp":1467331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IET Nanobiotechnology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>\n                    <jats:italic>\n                      Aim\n                      <jats:bold>:<\/jats:bold>\n                    <\/jats:italic>\n                    The authors report the biological synthesis of zinc oxide nanoparticles (ZnO\u2010NPs) from the petals extract of\n                    <jats:italic>Rosa indica<\/jats:italic>\n                    L. (rose). Its efficacy was evaluated against two dermatophytes: namely:\n                    <jats:italic>Trichophyton mentagrophytes<\/jats:italic>\n                    and\n                    <jats:italic>Microsporum canis<\/jats:italic>\n                    which cause onychomycosis. The activity of antibiotics against the tested dermatophytes was enhanced, when evaluated in combination with ZnO\u2010NPs.\n                    <jats:italic>Methods and results:<\/jats:italic>\n                    The synthesised ZnO\u2010NPs were preliminary detected by using ultraviolet UV visible spectroscopy, which showed specific absorbance. The ZnO\u2010NPs were further characterised by nanoparticle tracking analysis (NTA), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), X\u2010ray diffraction and Zetasizer. Moreover, nanoparticles containing nail paint (nanopaint) was formulated and its antifungal activity was also assessed against\n                    <jats:italic>T. mentagrophytes<\/jats:italic>\n                    and\n                    <jats:italic>M. canis<\/jats:italic>\n                    . ZnO\u2010NPs and formulated nanopaint containing ZnO\u2010NPs, both showed significant antifungal activity. The maximum activity was noted against\n                    <jats:italic>M. canis<\/jats:italic>\n                    and lesser against\n                    <jats:italic>T. mentagrophytes.<\/jats:italic>\n                    Minimum inhibitory concentration of ZnO\u2010NPs was also determined against the dermatophytes causing onychomycosis infection.\n                    <jats:italic>Conclusion:<\/jats:italic>\n                    ZnO\u2010NPs can be utilised as a potential antifungal agent for the treatment of onychomycosis after more experimental trials.\n                  <\/jats:p>","DOI":"10.1049\/iet-nbt.2016.0003","type":"journal-article","created":{"date-parts":[[2016,5,20]],"date-time":"2016-05-20T12:59:39Z","timestamp":1463749179000},"page":"205-211","source":"Crossref","is-referenced-by-count":60,"title":["Biosynthesis of zinc oxide nanoparticles by petals extract of\n                    <i>Rosa indica<\/i>\n                    L., its formulation as nail paint and evaluation of antifungal activity against fungi causing onychomycosis"],"prefix":"10.1049","volume":"11","author":[{"given":"Nikita","family":"Tiwari","sequence":"first","affiliation":[{"name":"Department of Biotechnology SGB Amravati University Amravati 444 602 Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raksha","family":"Pandit","sequence":"additional","affiliation":[{"name":"Department of Biotechnology SGB Amravati University Amravati 444 602 Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swapnil","family":"Gaikwad","sequence":"additional","affiliation":[{"name":"Department of Biotechnology SGB Amravati University Amravati 444 602 Maharashtra India"},{"name":"Department of Biotechnology Engineering School of Lorena, University of Sao Paulo Estrada Municipal do, Campinho, sn 12602\u2010810 Lorena SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1966-999X","authenticated-orcid":false,"given":"Aniket","family":"Gade","sequence":"additional","affiliation":[{"name":"Department of Biotechnology SGB Amravati University Amravati 444 602 Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahendra","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Biotechnology SGB Amravati University Amravati 444 602 Maharashtra India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"265","published-online":{"date-parts":[[2016,7]]},"reference":[{"issue":"5","key":"e_1_2_6_2_1","first-page":"380","article-title":"In vitro antifungal activity of allicin alone and in combination with two medication against six dermatophytic fungi","volume":"4","author":"Aala F.","year":"2010","journal-title":"Afr. 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