{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:07:48Z","timestamp":1788872868185,"version":"build-2803163510"},"reference-count":35,"publisher":"Institution of Engineering and Technology (IET)","issue":"8","license":[{"start":{"date-parts":[[2017,8,10]],"date-time":"2017-08-10T00:00:00Z","timestamp":1502323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IET Nanobiotechnology"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:p>\n                    To grapple with multidrug resistant bacterial infections, implementations of antibacterial nanomedicines have gained prime attention of the researchers across the globe. Nowadays, zinc oxide (ZnO) at nano\u2010scale has emerged as a promising antibacterial therapeutic agent. Keeping this in view, ZnO nanostructures (ZnO\u2010NS) have been synthesised through reduction by\n                    <jats:italic>P. aphylla<\/jats:italic>\n                    aqueous extract without the utilisation of any acid or base. Structural examinations via scanning electron microscopy (SEM) and X\u2010ray diffraction have revealed pure phase morphology with highly homogenised average particle size of 18\u00a0nm. SEM findings were further supplemented by transmission electron microscopy examinations. The characteristic Zn\u2013O peak has been observed around 363\u00a0nm using ultra\u2010violet\u2013visible spectroscopy. Fourier\u2010transform infrared spectroscopy examination has also confirmed the formation of ZnO\u2010NS through detection of Zn\u2013O bond vibration frequencies. To check the superior antibacterial activity of ZnO\u2010NS, the authors' team has performed disc diffusion assay and colony forming unit testing against multidrug resistant\n                    <jats:italic>E. coli, S. marcescens<\/jats:italic>\n                    and\n                    <jats:italic>E. cloacae<\/jats:italic>\n                    . Furthermore, protein kinase inhibition assay and cytotoxicity examinations have revealed that green fabricated ZnO\u2010NS are non\u2010hazardous, economical, environmental friendly and possess tremendous potential to treat lethal infections caused by multidrug resistant pathogens.\n                  <\/jats:p>","DOI":"10.1049\/iet-nbt.2016.0238","type":"journal-article","created":{"date-parts":[[2017,7,22]],"date-time":"2017-07-22T22:12:51Z","timestamp":1500761571000},"page":"935-941","source":"Crossref","is-referenced-by-count":10,"title":["Green synthesised zinc oxide nanostructures through\n                    <i>Periploca aphylla<\/i>\n                    extract shows tremendous antibacterial potential against multidrug resistant pathogens"],"prefix":"10.1049","volume":"11","author":[{"given":"Fazal","family":"Abbas","sequence":"first","affiliation":[{"name":"Department of Physics Government Post Graduate College Chakwal 48800 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qaisar","family":"Maqbool","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Virtual University of Pakistan Lahore 54000 Pakistan"},{"name":"Preston University Islamabad Campus Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mudassar","family":"Nazar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Virtual University of Pakistan Lahore 54000 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nyla","family":"Jabeen","sequence":"additional","affiliation":[{"name":"Applied Biotechnology and Genetic Engineering Laboratory Department of Bioinformatics and Biotechnology International Islamic University Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Zaheer","family":"Hussain","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences Quaid\u2010i\u2010Azam University Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadaf","family":"Anwaar","sequence":"additional","affiliation":[{"name":"Applied Biotechnology and Genetic Engineering Laboratory Department of Bioinformatics and Biotechnology International Islamic University Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasir","family":"Mehmood","sequence":"additional","affiliation":[{"name":"Department of Plant Pathology PMAS\u2010Arid Agriculture University Rawalpindi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Saleem","family":"Sheikh","sequence":"additional","affiliation":[{"name":"Preston University Islamabad Campus Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talib","family":"Hussain","sequence":"additional","affiliation":[{"name":"National Institute of Vacuum Science and Technology (NINVAST) Islamabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidra","family":"Iftikhar","sequence":"additional","affiliation":[{"name":"Department of Mathematics Virtual University of Pakistan Lahore 54000 Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"265","published-online":{"date-parts":[[2017,8,10]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature17042"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro3380"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2008.09.034"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198805053181818"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2008.tb01586.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/380449"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.00392"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.4962660"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl101807g"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpls.2016.01330"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-28030-6_4"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2008.09.020"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S113508"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/2228-5326-2-21"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep04134"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/17435390.2012.742935"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1039\/b207789b"},{"issue":"6","key":"e_1_2_5_19_1","first-page":"1806","article-title":"Methods of preparation of nanoparticles\u2010a review","volume":"7","author":"Rajput N.","year":"2015","journal-title":"Int. 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