{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T04:19:53Z","timestamp":1780633193072,"version":"3.54.1"},"reference-count":41,"publisher":"Institution of Engineering and Technology (IET)","issue":"6","license":[{"start":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T00:00:00Z","timestamp":1594684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["ietresearch.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["IET Nanobiotechnology"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p>\n                    In this examination, we researched the advantages of DNA fragmentation and metallic nanoparticles well\u2010appointed with biomolecules. A novel interpretation of DNA damage by Silver Nano\u2010Clusters (AgNCs) which were developed by the utilization of green synthesis method was demonstrated. The green synthesis of AgNCs was accomplished by utilizing the leaf extract of\n                    <jats:italic>Salacia mulbarica<\/jats:italic>\n                    (SM). The preparation of SM\u2010AgNCs was developed by estimating surface plasmon resonance peak around 449\u00a0nm by using a UV\u2013Visible spectrophotometer. The effect of phytochemicals in SM leaf extract on the development of stable SM\u2010AgNCs was confirmed by FTIR spectroscopy. The size of the fabricated SM\u2010AgNCs was estimated by dynamic light scattering and zeta\u2010sizer analysis and the morphology of the SM\u2010AgNCs was examined by transmission electron microscopy. The presence of clusters of Ag particles in the prepared SM\u2010AgNCs was recognized by energy dispersion X\u2010ray analysis. The results show that saponins, phytosterols, and phenolic compounds present in plant extract may play a great part in developing the SM\u2010AgNCs in their specialized particles. The succeeded SM\u2010AgNCs shows incredible anti\u2010bacterial action towards\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic>Bacillus subtilis<\/jats:italic>\n                    . In\u2010light of the antibacterial study, these SM\u2010AgNCs were analyzed with calf thymus\u2010DNA and found significant damage to the strand of thymus\u2010DNA.\n                  <\/jats:p>","DOI":"10.1049\/iet-nbt.2020.0001","type":"journal-article","created":{"date-parts":[[2020,5,5]],"date-time":"2020-05-05T22:46:51Z","timestamp":1588718811000},"page":"485-490","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Salacia mulbarica leaf extract mediated synthesis of silver nanoparticles for antibacterial and ct\u2010DNA damage via releasing of reactive oxygen species"],"prefix":"10.1049","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9838-0942","authenticated-orcid":false,"given":"Chandra Sekhar","family":"Espenti","sequence":"first","affiliation":[{"name":"Department of Chemistry Rajeev Gandhi Memorial College of Engineering and Technology Kurnool Nandyal Andhra Pradesh 518501 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kummari Subba Venkata","family":"Krishna Rao","sequence":"additional","affiliation":[{"name":"Department of Chemistry Polymer Biomaterial Synthesis and Design Laboratory Yogi Vemana University Kadapa Andhra Pradesh 516003 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palakurthi","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Yogi Vemana University Kadapa Andhra Pradesh 516003 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akila","family":"Chandra Sekhar","sequence":"additional","affiliation":[{"name":"Department of Biotechnology Yogi Vemana University Kadapa Andhra Pradesh 516003 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kummara","family":"Madhusudana Rao","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering, Yeungnam University 280\u2010Daehak\u2010Ro Gyeongsan 712\u2010749 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"265","published-online":{"date-parts":[[2020,7,14]]},"reference":[{"issue":"5","key":"e_1_2_5_2_1","first-page":"184","article-title":"One\u2010pot multi\u2010enzymatic production of purine derivatives with application in pharmaceutical and food industry","volume":"8","author":"Acosta J.","year":"2018","journal-title":"Catalysts"},{"issue":"2","key":"e_1_2_5_3_1","first-page":"102","article-title":"\u2018Green synthesis of gold nanoparticles using Prosopis Juliflora leaves extract and evaluation of their anti\u2010bacterial Activity'","volume":"5","author":"Krishna Rao K.S.V.","year":"2017","journal-title":"Ind. 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