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To evaluate the anti\u2010cancer property of CdO NPs, c\u2010MWCNT NPs and CdO NPs\/c\u2010MWCNT nanocomposite fibres, an anti\u2010proliferative assay test (Methylthiazolyl diphenyl\u2010 tetrazolium bromide \u2010 MTT assay) were performed on HeLa cells which further estimated IC50 value (Least concentration of sample in which nearly 50% of cells remain alive) under in\u2010vitro conditions. On comparison, CdONPs\/c\u2010MWCNT based system was found to be superior by achieving 52.3% cell viability with its minimal IC50 value of 31.2 \u03bcg\/ml. Lastly, the CdO NPs based system was taken up for an apoptotic study using DNA fragmentation assay for estimating its ability to cleave the DNA of the HeLa cells into internucleosomal fragments using the agarose gel electrophoresis method. In conclusion, based on our observations, CdO NPs\/c\u2010MWCNT hybrid based system can be further used for the development of efficient drug delivery and therapeutic systems.<\/jats:p>","DOI":"10.1049\/iet-nbt.2020.0020","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T22:48:32Z","timestamp":1600296512000},"page":"695-700","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["CdO nanoparticles, c\u2010MWCNT nanoparticles and CdO nanoparticles\/c\u2010MWCNT nanocomposite fibres: in vitro assessment of anti\u2010proliferative and apoptotic studies in HeLa cancer cell line"],"prefix":"10.1049","volume":"14","author":[{"given":"Jayaraman","family":"Saranya","sequence":"first","affiliation":[{"name":"Department of Electronics and Communication Engineering Rajalakshmi Engineering College Thandalam 602105 Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balakrishnapillai Suseela","family":"Sreeja","sequence":"additional","affiliation":[{"name":"Materials and MEMS Laboratory Department of Electronics and Communication Engineering SSN College of Engineering Kalavakkam 603110 Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1895-6479","authenticated-orcid":false,"given":"Gurunathan","family":"Padmalaya","sequence":"additional","affiliation":[{"name":"Materials and MEMS Laboratory Department of Electronics and Communication Engineering SSN College of Engineering Kalavakkam 603110 Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sankararajan","family":"Radha","sequence":"additional","affiliation":[{"name":"Materials and MEMS Laboratory Department of Electronics and Communication Engineering SSN College of Engineering Kalavakkam 603110 Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ponnusamy","family":"Senthil Kumar","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering SSN College of Engineering Kalavakkam 603110 Tamilnadu India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"265","published-online":{"date-parts":[[2020,9,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1825"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep20051"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201704290"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100400"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-018-0408-4"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40097-017-0239-0"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mssp.2016.12.004"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.materresbull.2013.12.060"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.06.015"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2014.03.021"},{"key":"e_1_2_5_12_1","first-page":"54","article-title":"Study of electrical properties of cadmium oxide nanoparticles embedded with AnnonaReticulata plant extract for cervical cancer applications","volume":"8","author":"Saranya J.","year":"2017","journal-title":"J. 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