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In this study, the authors developed the method to achieve apatite\u2010forming ability in Zr alloy within 1\u00a0day in SBF by a combination with apatite nuclei that promote apatite formation in SBF. First, Zr\u2013Sn alloy was soaked in concentrated sulphuric acid, and pores in micro\u2010level were formed on the surface of Zr\u2013Sn alloy. To attain apatite forming ability in Zr\u2013Sn alloy, second, apatite nuclei were formed in the micropores. To evaluate apatite\u2010forming ability, thus\u2010obtained Zr\u2013Sn alloy with apatite nuclei was soaked in SBF; hydroxyapatite formation was observed on the whole surface of the Zr\u2013Sn alloy plates. From this result, it was clarified that higher apatite\u2010forming ability was attained on the apatite nuclei\u2010treated Zr\u2013Sn alloy with micropores in comparison with that without micropores. When adhesive strength of formed hydroxyapatite film with respect to Zr\u2013Sn alloy plates was measured, high\u2010adhesive strength of the formed apatite film was attained by forming micropores and subsequently precipitating apatite nuclei in the fabrication process because of an interlocking effect caused by hydroxyapatite formed in the micropores.<\/jats:p>","DOI":"10.1049\/iet-nbt.2020.0051","type":"journal-article","created":{"date-parts":[[2020,9,16]],"date-time":"2020-09-16T22:27:52Z","timestamp":1600295272000},"page":"701-706","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Development of bioactive zirconium\u2013tin alloy by combination of micropores formation and apatite nuclei deposition"],"prefix":"10.1049","volume":"14","author":[{"given":"Norihiro","family":"Hashimoto","sequence":"first","affiliation":[{"name":"Department of Fundamental Energy Science Graduate School of Energy Science Kyoto University Yoshida\u2010honmachi, Sakyo\u2010ku Kyoto 606\u20108501 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2111-7470","authenticated-orcid":false,"given":"Takeshi","family":"Yabutsuka","sequence":"additional","affiliation":[{"name":"Department of Fundamental Energy Science Graduate School of Energy Science Kyoto University Yoshida\u2010honmachi, Sakyo\u2010ku Kyoto 606\u20108501 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeomi","family":"Takai","sequence":"additional","affiliation":[{"name":"Department of Fundamental Energy Science Graduate School of Energy Science Kyoto University Yoshida\u2010honmachi, Sakyo\u2010ku Kyoto 606\u20108501 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"265","published-online":{"date-parts":[[2020,9,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1049\/iet-nbt.2016.0047"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmst.2013.12.006"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surfcoat.2006.07.058"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.2320\/jinstmet.75.445"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(01)00110-7"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surfcoat.2013.10.039"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2016.11.012"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781439832530"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820240607"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2006.01.017"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1533\/9781845694227.1.165"},{"key":"e_1_2_6_13_1","unstructured":"YaoT. 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