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The modified nanosorbent\u00a0was investigated with Fourier transform infrared spectroscopy and thermogravimetric analysis. The particle size of the modified nanosorbent was studied with scanning electron microscopy. Some characteristic factors of the adsorption process such as pH and time were investigated for famotidine using the modified nanosorbent. The equilibrium adsorption study of famotidine by 3\u2010aminophenol\u2010grafted AGE\/ZnS was analysed by adsorption isotherms of the Langmuir, Freundlich, and Temkin models. The famotidine\u2010releasing process was investigated in simulated biological fluids (intestinal fluid at pH\u00a0of\u00a07.4 and gastric fluid at pH\u00a0of 1.2) and demonstrated 65% and 73% famotidine release during periods of 30\u00a0h (pH\u00a0=\u00a07.4) and 60\u00a0min (pH\u00a0=\u00a01.2), respectively. These results reveal the optimal performance of 3\u2010aminophenol\u2010grafted AGE\/ZnS for sustained drug delivery.<\/jats:p>","DOI":"10.1049\/nbt2.12063","type":"journal-article","created":{"date-parts":[[2021,6,11]],"date-time":"2021-06-11T23:10:35Z","timestamp":1623453035000},"page":"664-673","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Design of 3\u2010aminophenol\u2010grafted polymer\u2010modified zinc sulphide nanoparticles as drug delivery system"],"prefix":"10.1049","volume":"15","author":[{"given":"Milad","family":"Abniki","sequence":"first","affiliation":[{"name":"Department of Chemistry, Karaj Branch Islamic Azad University  Karaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5255-8311","authenticated-orcid":false,"given":"Zahra","family":"Azizi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Karaj Branch Islamic Azad University  Karaj Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Homayon Ahmad","family":"Panahi","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Central Tehran Branch Islamic Azad University  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"265","published-online":{"date-parts":[[2021,6,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1039\/d0ra02091e"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsusc.2019.144028"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2298\/jsc191011004a"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/app.45527"},{"key":"e_1_2_5_6_1","first-page":"105","volume-title":"IET Nanobiotechnology","author":"Ziaaddini V.","year":"2020"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.2014.01043"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.22153"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1039\/c5ra02933c"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10904\u2010018\u20100968\u20107"},{"issue":"1","key":"e_1_2_5_11_1","first-page":"100076","article-title":"Orderly porous covalent organic frameworks\u2010based materials: superior adsorbents for pollutants removal from aqueous solutions","volume":"2","author":"Liu X.","year":"2021","journal-title":"Innovation"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.143333"},{"issue":"8","key":"e_1_2_5_13_1","first-page":"1","article-title":"Recent developments of doped g\u2010C3N4 photocatalysts for the degradation of organic pollutants","volume":"51","author":"Liu X.","year":"2020","journal-title":"Crit. 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