{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:27:00Z","timestamp":1762352820810},"reference-count":21,"publisher":"EDP Sciences","issue":"1-2","license":[{"start":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T00:00:00Z","timestamp":1562284800000},"content-version":"vor","delay-in-days":185,"URL":"https:\/\/www.edpsciences.org\/en\/authors\/copyright-and-licensing"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biologie Aujourd\u2019hui"],"published-print":{"date-parts":[[2019]]},"abstract":"<jats:p>La migraine a une pr\u00e9valence estim\u00e9e entre 10 et 14\u2009%, elle est donc la pathologie neurologique la plus fr\u00e9quente. Elle concerne une population jeune, dont deux tiers de femmes, et son impact en termes \u00e9conomiques est essentiellement en lien avec les co\u00fbts indirects. La migraine peut \u00eatre \u00e9pisodique ou chronique en fonction de la fr\u00e9quence de jours de c\u00e9phal\u00e9e (\u2265\u200915\u2009jours par mois). Le diagnostic est pos\u00e9 \u00e0 l\u2019interrogatoire selon des crit\u00e8res internationaux. La migraine s\u2019explique par une activation du syst\u00e8me dit trig\u00e9minocervical, avec lib\u00e9ration en cascade de neurom\u00e9diateurs participant \u00e0 l\u2019inflammation neurog\u00e8ne et l\u2019activation des neurones de second ordre. La migraine avec aura se manifeste par des sympt\u00f4mes neurologiques, \u00e9voluant lors de la marche migraineuse, d\u2019une dur\u00e9e de moins de 60\u2009minutes, expliqu\u00e9s par le ph\u00e9nom\u00e8ne de d\u00e9polarisation corticale envahissante. Le traitement comporte deux axes\u2009: le traitement de crise par un anti-inflammatoire non st\u00e9ro\u00efdien (AINS) ou un triptan, et le traitement de fond prescrit au cas par cas, les mol\u00e9cules de premi\u00e8re intention selon les recommandations fran\u00e7aises \u00e9tant les b\u00eata-bloquants, puis en cas d\u2019\u00e9chec, le topiramate, l\u2019ox\u00e9torone ou l\u2019amitriptyline.<\/jats:p>","DOI":"10.1051\/jbio\/2019019","type":"journal-article","created":{"date-parts":[[2019,7,5]],"date-time":"2019-07-05T18:48:41Z","timestamp":1562352521000},"page":"35-41","source":"Crossref","is-referenced-by-count":3,"title":["Migraine\u2009: donn\u00e9es \u00e9pid\u00e9miologiques, cliniques et th\u00e9rapeutiques"],"prefix":"10.1051","volume":"213","author":[{"given":"Caroline","family":"Roos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"250","published-online":{"date-parts":[[2019,7,5]]},"reference":[{"key":"R1","first-page":"1","volume":"38","author":"Headache Classification Committee of the International Headache Society (IHS).","year":"2018","journal-title":"Cephalalgia"},{"key":"R2","first-page":"1023","volume":"24","author":"Bose","year":"2018","journal-title":"Continuum (Minneap Minn)"},{"key":"R3","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/S0140-6736(17)32154-2","volume":"390","author":"Disease","year":"2017","journal-title":"Lancet"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Donnet A., \nEmery C., \nAly S., \nAllaf B., \nCayre F., \nMahieu N., \nGourmelen J., \nL\u00e9vy P., \nFagnani F. \n(2019). \nMigraine burden and costs in France: a nationwide claims database analysis of triptan users. \nJ Med Econ, 1-9.","DOI":"10.1080\/13696998.2019.1590841"},{"key":"R5","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1152\/physrev.00034.2015","volume":"97","author":"Goadsby","year":"2017","journal-title":"Physiol Rev"},{"key":"R6","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1177\/0333102416678382","volume":"37","author":"Hepp","year":"2017","journal-title":"Cephalalgia"},{"key":"R7","doi-asserted-by":"crossref","first-page":"e0130733","DOI":"10.1371\/journal.pone.0130733","volume":"10","author":"Jackson","year":"2015","journal-title":"PLoS One"},{"key":"R8","doi-asserted-by":"crossref","first-page":"k80","DOI":"10.1136\/bmj.k80","volume":"360","author":"Jarvis","year":"2018","journal-title":"BMJ"},{"key":"R9","first-page":"996","volume":"24","author":"Karsan","year":"2018","journal-title":"Continuum (Minneap Minn)"},{"key":"R10","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1111\/j.1468-2982.1999.1901058.x","volume":"19","author":"Lampl","year":"1999","journal-title":"Cephalalgia"},{"key":"R11","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s10194-016-0599-8","volume":"17","author":"Lampl","year":"2016","journal-title":"J Headache Pain"},{"key":"R12","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.pain.2005.09.010","volume":"118","author":"Lant\u00e9ri-Minet","year":"2005","journal-title":"Pain"},{"key":"R13","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1111\/j.1526-4610.2011.01867.x","volume":"51","author":"Lant\u00e9ri-Minet","year":"2011","journal-title":"Headache"},{"key":"R14","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/1129-2377-15-2","volume":"15","author":"Lant\u00e9ri-Minet","year":"2014","journal-title":"J Headache Pain"},{"key":"R15","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1111\/j.1468-1331.2011.03612.x","volume":"19","author":"Linde","year":"2012","journal-title":"Eur J Neurol"},{"key":"R16","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1212\/01.wnl.0000252808.97649.21","volume":"68","author":"Lipton","year":"2007","journal-title":"Neurology"},{"key":"R17","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1111\/j.1526-4610.2009.01566.x","volume":"49","author":"Mathew","year":"2009","journal-title":"Headache"},{"issue":"Pt 1","key":"R18","first-page":"307","volume":"118","author":"Olsen","year":"1995","journal-title":"Brain"},{"key":"R19","unstructured":"Rainero I., \nVacca A., \nGovone F., \nGai A., \nPinessi L., \nRubino E. \n(2018). \nMigraine: genetic variants and clinical phenotypes. \nCurr Med Chem. PMID: 30027842."},{"key":"R20","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S1474-4422(11)70048-5","volume":"10","author":"Russell","year":"2011","journal-title":"Lancet Neurol"},{"key":"R21","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1468-1331.2006.01184.x","volume":"13","author":"Stovner","year":"2006","journal-title":"Eur J Neurol"}],"container-title":["Biologie Aujourd'hui"],"original-title":[],"link":[{"URL":"https:\/\/www.biologie-journal.org\/10.1051\/jbio\/2019019\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T17:46:52Z","timestamp":1584640012000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.biologie-journal.org\/10.1051\/jbio\/2019019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":21,"journal-issue":{"issue":"1-2"},"alternative-id":["jbio190019"],"URL":"https:\/\/doi.org\/10.1051\/jbio\/2019019","relation":{},"ISSN":["2105-0678","2105-0686"],"issn-type":[{"value":"2105-0678","type":"print"},{"value":"2105-0686","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}