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Au cours du d\u00e9veloppement postnatal, les m\u00e9canismes par lesquels le syst\u00e8me OT structure divers comportements sont peu explor\u00e9s. Nous pr\u00e9sentons ici le processus dynamique du d\u00e9veloppement postnatal du syst\u00e8me OT ainsi que ses r\u00f4les fonctionnels, en p\u00e9riode p\u00e9rinatale, qui sont essentiels pour fa\u00e7onner les comportements sociaux. Nous abordons sp\u00e9cifiquement le r\u00f4le de l\u2019OT chez le nouveau-n\u00e9, qui permet d\u2019int\u00e9grer et d\u2019adapter des r\u00e9ponses aux premi\u00e8res stimulations sensorielles et qui stimule aussi l\u2019activit\u00e9 de succion. Ce dialogue sensoriel et la t\u00e9t\u00e9e sont impliqu\u00e9s dans les liens m\u00e8re-enfant et structurent les futures interactions sociales. Chez les rongeurs et chez l\u2019homme, des maladies neuro-d\u00e9veloppementales avec des troubles du spectre autistique, comme les syndromes de Prader-Willi et de Schaaf-Yang, sont associ\u00e9es \u00e0 des d\u00e9ficiences sensorielles, alimentaires et comportementales dans la petite enfance. Nous proposons qu\u2019au d\u00e9but de la vie postnatale, l\u2019OT joue un r\u00f4le cl\u00e9 dans la maturation des r\u00e9seaux neuronaux contr\u00f4lant le comportement alimentaire et les premi\u00e8res interactions sociales. Une administration d\u2019OT chez le nouveau-n\u00e9 am\u00e9liore l\u2019int\u00e9gration sensorielle des facteurs environnementaux et la relation avec la m\u00e8re ainsi que l\u2019activit\u00e9 de succion comme nous l\u2019avons montr\u00e9 chez des mod\u00e8les de souris ainsi que chez des b\u00e9b\u00e9s atteints du syndrome de Prader-Willi. Des effets \u00e0 long terme ont aussi \u00e9t\u00e9 observ\u00e9s sur le comportement social et cognitif. Par cons\u00e9quent, les difficult\u00e9s pr\u00e9coces d\u2019alimentation peuvent \u00eatre un marqueur pr\u00e9dictif pr\u00e9coce des cas de troubles du spectre autistique (TSA) et l\u2019administration exog\u00e8ne d\u2019OT pourrait am\u00e9liorer le comportement alimentaire et, \u00e0 plus long terme, les troubles du comportement social.<\/jats:p>","DOI":"10.1051\/jbio\/2022017","type":"journal-article","created":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T08:56:48Z","timestamp":1675673808000},"page":"131-143","source":"Crossref","is-referenced-by-count":1,"title":["L\u2019ocytocine, d\u00e8s la naissance, conditionne le comportement alimentaire et social d\u2019un individu"],"prefix":"10.1051","volume":"216","author":[{"given":"Fran\u00e7oise","family":"Muscatelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"250","published-online":{"date-parts":[[2023,2,6]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1016\/j.nut.2012.01.007","volume":"28","author":"Al-Farsi","year":"2012","journal-title":"Nutrition"},{"key":"R2","first-page":"129328","volume":"2012","author":"Alberts","year":"2012","journal-title":"Int J Pediatr"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Althammer F., Grinevich V. 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