{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T09:57:30Z","timestamp":1773395850654,"version":"3.50.1"},"reference-count":14,"publisher":"EDP Sciences","issue":"1","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Extra Corpor Technol","JECT"],"accepted":{"date-parts":[[2025,9,11]]},"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    : A 17-year-old male patient diagnosed with a single ventricle, in a failed Fontan stage, was evaluated prior to heart transplantation. The patient had a panel-reactive antibody (PRA) for human leucocyte antigen (HLA) I of 18% and for HLA II of 37%, so the decision was made to administer three doses of immunoglobulin while waiting for a donor heart.\n                    <jats:italic>Methods<\/jats:italic>\n                    : Once extracorporeal circulation was initiated, the apheresis machine extracted blood from the patient\u2019s venous drainage and returned it to the oxygenator reservoir. A total of 8278\u00a0mL of blood was processed, and 4224\u00a0mL of plasma was extracted. For replacement, 1341\u00a0mL of fresh frozen plasma and 2700\u00a0mL of 5% albumin were used. 75\u00a0mL of citrate-dextrose acid (CDA) was used as an anticoagulant. The procedure lasted 135\u00a0min.\n                    <jats:italic>Results<\/jats:italic>\n                    : On the tenth postoperative day, the PRA for HLA I and II was 0%. On the thirtieth postoperative day, a catheterization with endomyocardial biopsy showed no evidence of immunological rejection. An echocardiogram showed good function of the heart graft. One year later, a catheterization with endomyocardial biopsy showed no signs of humoral rejection. The patient is currently in the third-year post-transplant and continues to show no signs of rejection in their progression.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    : Plasmapheresis during cardiopulmonary bypass is a reproducible, safe, and effective technique. It may be indicated for sensitized patients on the heart transplant waiting list.\n                  <\/jats:p>","DOI":"10.1051\/ject\/2025053","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T18:43:00Z","timestamp":1759430580000},"page":"79-84","source":"Crossref","is-referenced-by-count":0,"title":["Use of plasmapheresis during cardiopulmonary bypass in a pediatric heart transplant of a patient with Failing Fontan Physiology: first case in Argentina"],"prefix":"10.1051","volume":"58","author":[{"given":"Matias Jorge","family":"Martinez","sequence":"first","affiliation":[{"name":"Cardiovascular Surgery, Heart Transplant and Peripheral Vascular Service. Prof. Dr. Juan P. Garrahan Pediatric Hospital","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignacio","family":"Berra","sequence":"additional","affiliation":[{"name":"Cardiovascular Surgery, Heart Transplant and Peripheral Vascular Service. Prof. Dr. Juan P. Garrahan Pediatric Hospital","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Cornelis","sequence":"additional","affiliation":[{"name":"Cardiovascular Surgery, Heart Transplant and Peripheral Vascular Service. Prof. Dr. Juan P. Garrahan Pediatric Hospital","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Costilla","sequence":"additional","affiliation":[{"name":"Cardiovascular Surgery, Heart Transplant and Peripheral Vascular Service. Prof. Dr. Juan P. Garrahan Pediatric Hospital","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Zamora","sequence":"additional","affiliation":[{"name":"Hemotherapy and Transfusion Medicine Service. Prof. Dr. Juan P. Garrahan Pediatric Hospital, Combate de los Pozos 1881 (1245)","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo Garcia","family":"Delucis","sequence":"additional","affiliation":[{"name":"Cardiovascular Surgery, Heart Transplant and Peripheral Vascular Service. Prof. Dr. Juan P. Garrahan Pediatric Hospital","place":["Argentina"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"250","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"R1","unstructured":"American Association of Blood Banks. The HLA system. Technical manual. Chapter 19, 17th edn.; 2012."},{"key":"R2","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2001-1326-2-6","volume":"2","author":"Mahdi","year":"2013","journal-title":"Clin Transl Med."},{"issue":"5","key":"R3","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1161\/01.CIR.94.5.1063","volume":"94","author":"Shaddy","year":"1996","journal-title":"Circulation"},{"issue":"2","key":"R4","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0022-5223(00)70188-7","volume":"119","author":"Hawkins","year":"2000","journal-title":"J Thorac Cardiovasc Surg"},{"key":"R5","doi-asserted-by":"publisher","first-page":"e553","DOI":"10.1161\/CIR.0000000000000598","volume":"139","author":"Colvin","year":"2019","journal-title":"Circulation"},{"issue":"4","key":"R6","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.trre.2009.07.001","volume":"23","author":"V\u00e9lez","year":"2009","journal-title":"Trasplante Rev (Orlando)"},{"key":"R7","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1002\/jca.22043","volume":"38","author":"Padmanabhan","year":"2019","journal-title":"J Clin Apher"},{"key":"R8","unstructured":"American Association of Blood Banks. Therapeutic apheresis, Chapter 26, 17th edn.; 2012."},{"issue":"6","key":"R9","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1002\/jca.20151","volume":"22","author":"Jhang","year":"2007","journal-title":"J Clin Apher"},{"issue":"4","key":"R10","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1067\/mtc.2001.111383","volume":"121","author":"Dellgren","year":"2001","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"2","key":"R11","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1177\/0267659120974324","volume":"37","author":"Kassif Lerner","year":"2022","journal-title":"Perfusion."},{"key":"R12","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.xjon.2020.05.002","volume":"3","author":"Rajab","year":"2020","journal-title":"JTCVS Open"},{"key":"R13","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.xjtc.2022.01.020","volume":"13","author":"Konstantinov","year":"2022","journal-title":"JTCVS Techniques"},{"issue":"4","key":"R14","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1051\/ject\/1999314177","volume":"31","author":"Larson","year":"1999","journal-title":"J Extra Corpor Technol."}],"container-title":["The Journal of ExtraCorporeal Technology"],"original-title":[],"link":[{"URL":"https:\/\/ject.edpsciences.org\/10.1051\/ject\/2025053\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T08:53:41Z","timestamp":1773392021000},"score":1,"resource":{"primary":{"URL":"https:\/\/ject.edpsciences.org\/10.1051\/ject\/2025053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":14,"journal-issue":{"issue":"1"},"alternative-id":["ject250026"],"URL":"https:\/\/doi.org\/10.1051\/ject\/2025053","relation":{},"ISSN":["0022-1058","2969-8960"],"issn-type":[{"value":"0022-1058","type":"print"},{"value":"2969-8960","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]}}}