{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T08:50:47Z","timestamp":1781859047892,"version":"3.54.5"},"reference-count":19,"publisher":"EDP Sciences","issue":"2","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Extra Corpor Technol","JECT"],"accepted":{"date-parts":[[2025,10,12]]},"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>\n                    Extracorporeal carbon dioxide removal (ECCO\n                    <jats:sub>2<\/jats:sub>\n                    R) has emerged as a promising adjunctive therapy to mitigate hypercapnia and reduce invasive mechanical ventilation (IMV) settings. We present the cases of two post-lung transplant patients with severe hypercapnia and respiratory failure who were successfully treated with the ECCO\n                    <jats:sub>2<\/jats:sub>\n                    R. In both cases, we used a venovenous ECCO\n                    <jats:sub>2<\/jats:sub>\n                    R (V-ECCO\n                    <jats:sub>2<\/jats:sub>\n                    R) system, employing the Prismalung\u2122 oxygenator integrated into a Prismaflex\u2122 continuous renal replacement therapy (CRRT) platform. This technique proved efficacy in correcting hypercapnia, improving ventilatory parameters, and facilitating lung-protective strategies in post-lung transplant patients with respiratory failure. This technique represents a valuable adjunct to conventional mechanical ventilation, particularly in cases where hypercapnia poses a risk to graft function and patient stability. Further studies are warranted to establish optimal patient selection and refine treatment protocols for ECCO\n                    <jats:sub>2<\/jats:sub>\n                    R implementation in critical care settings.\n                  <\/jats:p>","DOI":"10.1051\/ject\/2025063","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T19:44:20Z","timestamp":1761767060000},"page":"172-179","source":"Crossref","is-referenced-by-count":0,"title":["Extracorporeal carbon dioxide removal (ECCO\n                    <sub>2<\/sub>\n                    R) in post lung transplant patients"],"prefix":"10.1051","volume":"58","author":[{"given":"Mariana N.","family":"Zavala G\u00f3mez","sequence":"first","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Chinchilla Lopez","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Garza Trevino","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paola","family":"Borbolla","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Bernal Heinzel","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilberto","family":"Lozano Miranda","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"M\u00e9ndez","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uriel","family":"Chavarria Martinez","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]},{"name":"Clinical Director, Lung Transplant Program. Christus Muguerza Alta Especialidad","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Wong","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]},{"name":"Cardiothoracic and Lung Transplant Surgeon, Lung Transplant Program. Christus Muguerza Alta Especialidad","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"Camacho Ortiz","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]},{"name":"Infectology Lung Transplant Program, Christus Muguerza Alta Especialidad","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilia M.","family":"Rizo Topete","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]},{"name":"Nephrology of the Critically Ill Patient, Internal Medicine, Internal Medicine Professor, Department of Health Sciences, Christus Muguerza Health System","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio","family":"S\u00e1nchez Salazar","sequence":"additional","affiliation":[{"name":"Internal Medicine Residents, Department of Health Sciences, Christus Muguerza Health System, UDEM","place":["M\u00e9xico"]},{"name":"Pulmonary and Critical Care Medicine, Lung Transplant Program, Christus Muguerza Alta Especialidad","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2026,6,19]]},"reference":[{"issue":"9","key":"R1","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1164\/rccm.201703-0548ST","volume":"195","author":"Fan","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"18","key":"R2","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","volume":"342","author":"Brower","year":"2000","journal-title":"N Engl J Med"},{"issue":"5","key":"R3","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1164\/rccm.201404-0630CP","volume":"190","author":"Combes","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"R4","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/cc660","volume":"4","author":"Al\u00eda","year":"2000","journal-title":"Crit Care"},{"issue":"10","key":"R5","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S2213-2600(20)30393-3","volume":"8","author":"Cypel","year":"2020","journal-title":"Lancet Respir Med"},{"issue":"5","key":"R6","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/j.healun.2019.03.009","volume":"38","author":"Verleden","year":"2019","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"R7","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1186\/s13054-020-03210-z","volume":"24","author":"Combes","year":"2020","journal-title":"Critical Care"},{"issue":"5","key":"R8","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/aor.14130","volume":"46","author":"Yu","year":"2022","journal-title":"Artif Organs"},{"key":"R9","doi-asserted-by":"crossref","unstructured":"Fanelli V, Costamagna A, Ranieri VM. 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