{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:34:39Z","timestamp":1791128079101,"version":"4.1.0"},"reference-count":33,"publisher":"EDP Sciences","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2006,2]]},"DOI":"10.1051\/medsci\/2006222158","type":"journal-article","created":{"date-parts":[[2011,3,5]],"date-time":"2011-03-05T12:22:29Z","timestamp":1299327749000},"page":"158-163","source":"Crossref","is-referenced-by-count":12,"title":["Ecz\u00e9ma allergique de contact : Comment r\u00e9-induire une tol\u00e9rance\u00a0?"],"prefix":"10.1051","volume":"22","author":[{"given":"Marc","family":"Vocanson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Hennino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cyril","family":"Chavagnac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurore","family":"Rozi\u00e8res","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre","family":"Saint-Mezard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Akiba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masataka","family":"Satoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Kaiserlian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Nicolas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2006,2,15]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Saint-Mezard P, Rosieres A, Krasteva M,et al.Allergic contact dermatitis.Eur J Dermatol2004; 14 : 284\u201395.","DOI":"10.1201\/b14248-37"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Blauvelt A, Hwang ST, Udey MC. Allergic and immunologic diseases of the skin.J Allergy Clin Immunol2003; 111 : S560\u201370.","DOI":"10.1067\/mai.2003.78"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Belsito DV. The diagnostic evaluation, treatment, and prevention of allergic contact dermatitis in the new millennium.J Allergy Clin Immunol2000; 105 : 409\u201320.","DOI":"10.1067\/mai.2000.104937"},{"key":"R4","unstructured":"Revillard JP. Innate immunity.Eur J Dermatol2002; 12 : 224\u20137."},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Buckley DA, Rycroft RJ, White IR, McFadden JP. Fragrance as an occupational allergen.Occup Med (Lond)2002; 52 : 13\u20136.","DOI":"10.1093\/occmed\/52.1.13"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Akiba H, Kehren J, Ducluzeau MT,et al.Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+T cytotoxic 1 cells inducing keratinocyte apoptosis.J Immunol2002; 168 : 3079\u201387.","DOI":"10.4049\/jimmunol.168.6.3079"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Kehren J, Desvignes C, Krasteva M,et al.Cytotoxicity is mandatory for CD8+T cell-mediated contact hypersensitivity. J Exp Med1999; 189 : 779\u201386.","DOI":"10.1084\/jem.189.5.779"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Krasteva M, Kehren J, Horand F,et al.Dual role of dendritic cells in the induction and down-regulation of antigen-specific cutaneous inflammation.J Immunol1998; 160 : 1181\u201390.","DOI":"10.4049\/jimmunol.160.3.1181"},{"key":"R9","doi-asserted-by":"crossref","unstructured":"Bour H, Peyron E, Gaucherand M,et al.Major histocompatibility complex class I-restricted CD8+T cells and class II-restricted CD4+T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene.Eur J Immunol1995; 25 : 3006\u201310.","DOI":"10.1002\/eji.1830251103"},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Cavani A, Albanesi C, Traidl C,et al.Effector and regulatory T cells in allergic contact dermatitis.Trends Immunol2001; 22 : 118\u201320.","DOI":"10.1016\/S1471-4906(00)01815-9"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Dubois B, Chapat L, Goubier A,et al.Innate CD4+CD25+regulatory T cells are required for oral tolerance and inhibition of CD8+T cells mediating skin inflammation.Blood2003; 102 : 3295\u2013301.","DOI":"10.1182\/blood-2003-03-0727"},{"key":"R12","doi-asserted-by":"crossref","unstructured":"Cavani A, Nasorri F, Prezzi C,et al.Human CD4+T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses.J Invest Dermatol2000; 114 : 295\u2013302.","DOI":"10.1046\/j.1523-1747.2000.00881.x"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Xu H, DiIulio NA, Fairchild RL. T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production : interferon gamma-producing (Tc1) effector CD8+T cells and interleukin (Il) 4\/Il-10-producing (Th2) negative regulatory CD4+T cells.J Exp Med1996; 183 : 1001\u201312.","DOI":"10.1084\/jem.183.3.1001"},{"key":"R14","doi-asserted-by":"crossref","unstructured":"Paust S, Cantor H. Regulatory T cells and autoimmune disease.Immunol Rev2005; 204 : 195\u2013207.","DOI":"10.1111\/j.0105-2896.2005.00247.x"},{"key":"R15","doi-asserted-by":"crossref","unstructured":"Hawrylowicz CM, O\u2019Garra A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma.Nat Rev Immunol2005; 5 : 271\u201383.","DOI":"10.1038\/nri1589"},{"key":"R16","doi-asserted-by":"crossref","unstructured":"Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+regulatory T cells in immunological tolerance to self and non-self.Nat Immunol2005; 6 : 345\u201352.","DOI":"10.1038\/ni1178"},{"key":"R17","unstructured":"Dubois B, Chapat L, Goubier A, Kaiserlian D. CD4+CD25+T cells as key regulators of immune responses.Eur J Dermatol2003; 13 : 111\u20136."},{"key":"R18","doi-asserted-by":"crossref","unstructured":"Akdis CA, Blesken T, Akdis M,et al.Role of interleukin-10 in specific immunotherapy.J Clin Invest1998; 102 : 98\u2013106.","DOI":"10.1172\/JCI2250"},{"key":"R19","doi-asserted-by":"crossref","unstructured":"Dubois B, Goubier A, Joubert G, Kaiserlian D. Oral tolerance and regulation of mucosal immunity.Cell Mol Life Sci2005; 62 : 1322\u201332.","DOI":"10.1007\/s00018-005-5036-0"},{"key":"R20","doi-asserted-by":"crossref","unstructured":"Maurer M, Seidel-Guyenot W, Metz M,et al.Critical role of IL-10 in the induction of low zone tolerance to contact allergens.J Clin Invest2003; 112 : 432\u20139.","DOI":"10.1172\/JCI200318106"},{"key":"R21","doi-asserted-by":"crossref","unstructured":"Nakamura K, Kitani A, Strober W. Cell contact-dependent immunosuppression by CD4+CD25+regulatory T cells is mediated by cell surface-bound transforming growth factor beta.J Exp Med2001; 194 : 629\u201344.","DOI":"10.1084\/jem.194.5.629"},{"key":"R22","doi-asserted-by":"crossref","unstructured":"Gorbachev AV, Fairchild RL. CD4+T cells regulate CD8+T cell-mediated cutaneous immune responses by restricting effector T cell development through a Fas ligand-dependent mechanism.J Immunol2004; 172 : 2286\u201395.","DOI":"10.4049\/jimmunol.172.4.2286"},{"key":"R23","doi-asserted-by":"crossref","unstructured":"Foussat A, Cottrez F, Brun V,et al.A comparative study between T regulatory type 1 and CD4+CD25+T cells in the control of inflammation.J Immunol2003; 171 : 5018\u201326.","DOI":"10.4049\/jimmunol.171.10.5018"},{"key":"R24","doi-asserted-by":"crossref","unstructured":"Kish DD, Gorbachev AV, Fairchild RL. CD8+T cells produce IL-2, which is required for CD4+CD25+T cell regulation of effector CD8+T cell development for contact hypersensitivity responses.J Leukoc Biol2005; 78 : 725\u201335.","DOI":"10.1189\/jlb.0205069"},{"key":"R25","doi-asserted-by":"crossref","unstructured":"Ruckert R, Brandt K, Hofmann U,et al.IL-2-IgG2b fusion protein suppresses murine contact hypersensitivityin vivo.J Invest Dermatol2002; 119 : 370\u20136.","DOI":"10.1046\/j.1523-1747.2002.01849.x"},{"key":"R26","doi-asserted-by":"crossref","unstructured":"Isolauri E. Dietary modification of atopic disease : Use of probiotics in the prevention of atopic dermatitis.Curr Allergy Asthma Rep2004; 4 : 270\u20135.","DOI":"10.1007\/s11882-004-0070-9"},{"key":"R27","doi-asserted-by":"crossref","unstructured":"Chapat L, Chemin K, Dubois B,et al.Lactobacillus casei reduces CD8+T cell-mediated skin inflammation.Eur J Immunol2004; 34 : 2520\u20138.","DOI":"10.1002\/eji.200425139"},{"key":"R28","doi-asserted-by":"crossref","unstructured":"Desvignes C, Etchart N, Kehren J,et al.Oral administration of hapten inhibitsin vivoinduction of specific cytotoxic CD8+T cells mediating tissue inflammation : a role for regulatory CD4+T cells.J Immunol2000; 164 : 2515\u201322.","DOI":"10.4049\/jimmunol.164.5.2515"},{"key":"R29","unstructured":"Prystupa K, Rudzki E. Oral tolerance of nickel in patients with dyshidrosis. Contact Dermatitis 2000; 42 : 276\u20137."},{"key":"R30","unstructured":"Bagot M, Charue D, Flechet M,et al.Oral desensitization in nickel allergy induces a decrease in nickel-specific T cells. Eur J Dermatol 1995; 5 : 614\u20137."},{"key":"R31","doi-asserted-by":"crossref","unstructured":"Steinbrink K, Sorg C, Macher E. Low zone tolerance to contact allergens in mice : a functional role for CD8+T helper type 2 cells.J Exp Med1996; 183 : 759\u201368.","DOI":"10.1084\/jem.183.3.759"},{"key":"R32","unstructured":"Krasteva M, Aubin F, Laventurier S,et al.MHC class II-KO mice are resistant to the immunosuppressive effects of UV light.Eur J Dermatol2002; 12 : 10\u20139."},{"key":"R33","doi-asserted-by":"crossref","unstructured":"Schwarz A, Maeda A, Wild MK,et al.Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity.J Immunol2004; 172 : 1036\u201343.","DOI":"10.4049\/jimmunol.172.2.1036"}],"container-title":["m\u00e9decine\/sciences"],"original-title":[],"link":[{"URL":"http:\/\/www.medecinesciences.org\/10.1051\/medsci\/2006222158\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,5]],"date-time":"2023-06-05T14:21:53Z","timestamp":1685974913000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.medecinesciences.org\/10.1051\/medsci\/2006222158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2]]},"references-count":33,"journal-issue":{"issue":"2"},"alternative-id":["medsci2006222p158"],"URL":"https:\/\/doi.org\/10.1051\/medsci\/2006222158","relation":{},"ISSN":["0767-0974","1958-5381"],"issn-type":[{"value":"0767-0974","type":"print"},{"value":"1958-5381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2]]}}}