{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T01:52:58Z","timestamp":1791078778125,"version":"4.1.0"},"reference-count":31,"publisher":"EDP Sciences","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2010,4]]},"DOI":"10.1051\/medsci\/2010264391","type":"journal-article","created":{"date-parts":[[2011,3,5]],"date-time":"2011-03-05T06:13:59Z","timestamp":1299305639000},"page":"391-396","source":"Crossref","is-referenced-by-count":10,"title":["Leuc\u00e9mies T induites par HTLV-1"],"prefix":"10.1051","volume":"26","author":[{"given":"Madeleine","family":"Duc Dodon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beno\u00eet","family":"Barbeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Michel","family":"Mesnard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2010,4,15]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Cooper SA, van der Loeff MS, Taylor GP. The neurology of HTLV-1 infection.Pract Neurol2009; 9 : 16\u201326.","DOI":"10.1136\/jnnp.2008.167155"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Mahieux R, Hermine O.In vivoandin vitrotreatment of HTLV-1 and HTLV-2 infected cells with arsenic trioxide and interferon-alpha.Leuk Lymphoma2005; 46 : 347\u201355.","DOI":"10.1080\/10428190400019966"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Bangham CR. The immune response to HTLV-1.Curr Opin Immunol2000; 12 : 397\u2013402.","DOI":"10.1016\/S0952-7915(00)00107-2"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Mesnard JM, Devaux C. Multiple control levels of cell proliferation by human T-cell leukemia virus type 1 Tax protein.Virology1999; 257 : 277\u201384.","DOI":"10.1006\/viro.1999.9685"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Matsuoka M, Jeang KT. Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation.Nat Rev Cancer2007; 7 : 270\u201380.","DOI":"10.1038\/nrc2111"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Arpin-Andre C, Mesnard JM. The PDZ domain-binding motif of the human T cell leukemia virus type 1 Tax protein induces mislocalization of the tumor suppressor hScrib in T cells.J Biol Chem2007; 282 : 33132\u201341.","DOI":"10.1074\/jbc.M702279200"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Gabet AS, Mortreux F, Charneau P,et al.Inactivation of hTERT transcription by Tax.Oncogene2003; 22 : 3734\u201341.","DOI":"10.1038\/sj.onc.1206468"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Taylor GP, Matsuoka M. Natural history of adult T-cell leukemia\/lymphoma and approaches to therapy.Oncogene2005; 24 : 6047\u201357.","DOI":"10.1038\/sj.onc.1208979"},{"key":"R9","doi-asserted-by":"crossref","unstructured":"Gaudray G, Gachon F, Basbous J,et al.The complementary strand of HTLV-1 RNA genome encodes a bZIP transcription factor that down-regulates the viral transcription.J Virol2002; 76 : 12813\u201322.","DOI":"10.1128\/JVI.76.24.12813-12822.2002"},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Larocca D, Chao LA, Seto MH, Brunck TK. Human T-cell leukemia virus minus strand transcription in infected T-cells.Biochem Biophys Res Commun1989; 163 : 1006\u201313.","DOI":"10.1016\/0006-291X(89)92322-X"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Cavanagh MH, Landry S, Audet B,et al.HTLV-I antisense transcripts initiating in the 3\u2019LTR are alternatively spliced and polyadenylated.Retrovirology2006; 3 : 15.","DOI":"10.1186\/1742-4690-3-15"},{"key":"R12","doi-asserted-by":"crossref","unstructured":"Murata K, Hayashibara T, Sugahara K,et al.A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization.J Virol2006; 80 : 2495\u2013505.","DOI":"10.1128\/JVI.80.5.2495-2505.2006"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Satou Y, Yasunaga JI, Yoshida M, Matsuoka M. HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells.Proc Natl Acad Sci USA2006; 103 : 720\u201325.","DOI":"10.1073\/pnas.0507631103"},{"key":"R14","doi-asserted-by":"crossref","unstructured":"Usui T, Yanagihara K, Tsukasaki K,et al.Characteristic expression of HTLV-1 basic zipper factor (HBZ) transcripts in HTLV-1 provirus-positive cells.Retrovirology2008; 5 : 34.","DOI":"10.1186\/1742-4690-5-34"},{"key":"R15","doi-asserted-by":"crossref","unstructured":"Hivin P, Fr\u00e9d\u00e9ric M, Arpin-Andr\u00e9 C,et al.Nuclear localization of HTLV-I bZIP factor (HBZ) is mediated by three distinct motifs.J Cell Sci2005; 118 : 1355\u201362.","DOI":"10.1242\/jcs.01727"},{"key":"R16","doi-asserted-by":"crossref","unstructured":"Hivin P, Arpin-Andr\u00e9 C, Clerc I,et al.A modified version of a Fos-associated cluster in HBZ affects Jun transcriptional potency.Nucleic Acids Res2006; 34 : 2761\u201372.","DOI":"10.1093\/nar\/gkl375"},{"key":"R17","doi-asserted-by":"crossref","unstructured":"Basbous J, Arpin C, Gaudray G,et al.HBZ factor of HTLV-I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity.J Biol Chem2003; 278 : 43620\u201327.","DOI":"10.1074\/jbc.M307275200"},{"key":"R18","doi-asserted-by":"crossref","unstructured":"Th\u00e9bault S, Basbous J, Hivin P,et al.HBZ interacts with JunD and stimulates its transcriptional activity.FEBS Lett2004; 562 : 165\u201370.","DOI":"10.1016\/S0014-5793(04)00225-X"},{"key":"R19","doi-asserted-by":"crossref","unstructured":"Matsumoto J, Ohshima T, Isono O, Shimotohno K. HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein.Oncogene2005; 24 : 1001\u201310.","DOI":"10.1038\/sj.onc.1208297"},{"key":"R20","doi-asserted-by":"crossref","unstructured":"Hivin P, Basbous J, Raymond F,et al.The HBZ-SP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies.Retrovirology2007; 4 : 14.","DOI":"10.1186\/1742-4690-4-14"},{"key":"R21","doi-asserted-by":"crossref","unstructured":"Lemasson I, Lewis MR, Polakowski N,et al.Human T-cell leukemia virus type 1 (HTLV-1) bZIP protein interacts with the cellular transcription factor CREB to inhibit HTLV-1 transcription.J Virol2007; 81 : 1543\u201353.","DOI":"10.1128\/JVI.00480-06"},{"key":"R22","doi-asserted-by":"crossref","unstructured":"Clerc I, Polakowski N, Andre-Arpin C,et al.An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300\/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ.J Biol Chem2008; 283 : 23903\u201313.","DOI":"10.1074\/jbc.M803116200"},{"key":"R23","doi-asserted-by":"crossref","unstructured":"Yoshida M, Satou Y, Yasunaga J,et al.Transcriptional control of spliced and unspliced HTLV-1 bZIP factor gene.J Virol2008; 82 : 9359\u201368.","DOI":"10.1128\/JVI.00242-08"},{"key":"R24","doi-asserted-by":"crossref","unstructured":"Landry S, Halin M, Vargas A,et al.Upregulation of human T-cell leukemia virus type 1 antisense transcription by the viral tax protein.J Virol2009; 83 : 2048\u201354.","DOI":"10.1128\/JVI.01264-08"},{"key":"R25","doi-asserted-by":"crossref","unstructured":"Arnold J, Yamamoto B, Li M,et al.Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1.Blood2006; 107 : 3976\u201382.","DOI":"10.1182\/blood-2005-11-4551"},{"key":"R26","doi-asserted-by":"crossref","unstructured":"Li M, Kesic M, Yin H,et al.Kinetic analysis of human T-cell leukemia virus type 1 gene expression in cell culture and infected animals.J Virol2009; 83 : 3788\u201397.","DOI":"10.1128\/JVI.02315-08"},{"key":"R27","doi-asserted-by":"crossref","unstructured":"Saito M, Matsuzaki T, Satou Y,et al.In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy\/tropical spastic paraparesis (HAM\/TSP).Retrovirology2009; 6 : 19.","DOI":"10.1186\/1742-4690-6-19"},{"key":"R28","doi-asserted-by":"crossref","unstructured":"Suemori K, Fujiwara H, Ochi T,et al.HBZ is an immunogenic protein but not a target antigen for HTLV-1-specific cytotoxic T lymphocytes.J Gen Virol2009; 90 : 1806\u201311.","DOI":"10.1099\/vir.0.010199-0"},{"key":"R29","doi-asserted-by":"crossref","unstructured":"Arnold J, Zimmerman B, Li M,et al.Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation.Blood2008; 112 : 3788\u201397.","DOI":"10.1182\/blood-2008-04-154286"},{"key":"R30","doi-asserted-by":"crossref","unstructured":"Kuhlmann AS, Villaudy J, Gazzolo L,et al.HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse transcriptase gene (hTERT).Retrovirology2007; 4 : 92.","DOI":"10.1186\/1742-4690-4-92"},{"key":"R31","doi-asserted-by":"crossref","unstructured":"Manel N, Kinet S, Kim FJ,et al.GLUT-1 est le r\u00e9cepteur des r\u00e9trovirus humains HTLV.Med Sci (Paris)2004; 20 : 277\u20139.","DOI":"10.1051\/medsci\/2004203277"}],"container-title":["m\u00e9decine\/sciences"],"original-title":[],"link":[{"URL":"http:\/\/www.medecinesciences.org\/10.1051\/medsci\/2010264391\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,19]],"date-time":"2021-11-19T20:59:09Z","timestamp":1637355549000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.medecinesciences.org\/10.1051\/medsci\/2010264391"}},"subtitle":["Y a-t-il un avant et un apr\u00e8s HBZ\u00a0?"],"short-title":[],"issued":{"date-parts":[[2010,4]]},"references-count":31,"journal-issue":{"issue":"4"},"alternative-id":["medsci2010264p391"],"URL":"https:\/\/doi.org\/10.1051\/medsci\/2010264391","relation":{},"ISSN":["0767-0974","1958-5381"],"issn-type":[{"value":"0767-0974","type":"print"},{"value":"1958-5381","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,4]]}}}