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Les dispositions sp\u00e9cifiques de prise en charge pr\u00e9conis\u00e9es sont modul\u00e9es en fonction des g\u00e8nes, class\u00e9s en : (1) tr\u00e8s haut risque, tels les g\u00e8nes <jats:italic>BRCA1\/2<\/jats:italic> suivant les recommandations de l\u2019INCa 2017 ; (2) risque \u00e9lev\u00e9 ; (3) augmentation mod\u00e9r\u00e9e : dans ce dernier cas, les mesures de surveillance sont similaires \u00e0 la population g\u00e9n\u00e9rale. En l\u2019absence de mutation, d\u2019autres facteurs de risque peuvent intervenir et des scores professionnels \u00eatre calcul\u00e9s. Cependant, selon les recommandations de la HAS 2014, l\u2019histoire familiale pr\u00e9vaut : sur cette base, le dispositif national d\u2019oncog\u00e9n\u00e9tique de l\u2019INCa a mis en place un maillage national de r\u00e9seaux de suivi des personnes \u00e0 haut risque, pr\u00e9sentant ou non des mutations. 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