{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:54:43Z","timestamp":1790261683665,"version":"4.1.0"},"reference-count":15,"publisher":"EDP Sciences","issue":"12","license":[{"start":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T00:00:00Z","timestamp":1578268800000},"content-version":"vor","delay-in-days":36,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>Le d\u00e9veloppement des anticorps th\u00e9rapeutiques en infectiologie est beaucoup plus r\u00e9cent qu\u2019en canc\u00e9rologie, \u00e0 l\u2019exception d\u2019un anticorps anti-virus respiratoire syncytial (VRS), mais il est d\u00e9sormais un domaine en pleine expansion. \u00c0 l\u2019\u00e9chelle mondiale, sept de ces anticorps ont d\u00e9j\u00e0 \u00e9t\u00e9 approuv\u00e9s par des autorit\u00e9s de sant\u00e9, dont seulement cinq en France. \u00c0 ce jour, les indications sont restreintes \u00e0 la pr\u00e9vention de la bronchiolite li\u00e9e au VRS, au traitement de la maladie VIH\/Sida en \u00e9chec th\u00e9rapeutique, \u00e0 l\u2019exposition au virus de la rage et \u00e0 la maladie du charbon, \u00e0 la colite post-antibiotique \u00e0 <jats:italic>Clostridium difficile<\/jats:italic>, et au syndrome h\u00e9molytique et ur\u00e9mique atypique \u00e0 <jats:italic>Escherichia coli<\/jats:italic> ent\u00e9ro-h\u00e9morragique. 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