{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:44:24Z","timestamp":1790621064913,"version":"4.1.0"},"reference-count":55,"publisher":"EDP Sciences","issue":"8-9","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"vor","delay-in-days":37,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:p>Le syndrome de gr\u00eale court, cons\u00e9quence d\u2019une r\u00e9section \u00e9tendue de l\u2019intestin, est la principale cause d\u2019insuffisance intestinale, d\u00e9finie comme la r\u00e9duction de la fonction intestinale en dessous du minimum n\u00e9cessaire \u00e0 l\u2019absorption des macronutriments, de l\u2019eau et des \u00e9lectrolytes. La prise en charge n\u00e9cessite alors la nutrition parent\u00e9rale. L\u2019\u00e9volution du syndrome de gr\u00eale court est sch\u00e9matiquement scind\u00e9e en trois p\u00e9riodes successives : 1) la p\u00e9riode post-op\u00e9ratoire, d\u2019une dur\u00e9e de 3 \u00e0 6 semaines ; 2) la p\u00e9riode adaptative, d\u2019une dur\u00e9e de 2 ans environ ; et 3) la p\u00e9riode de stabilisation, dite s\u00e9quellaire. Le d\u00e9veloppement d\u2019une hyperphagie, d\u2019une adaptation intestinale permettant l\u2019augmentation de la surface d\u2019absorption et de la s\u00e9cr\u00e9tion d\u2019ent\u00e9rohormones, ainsi qu\u2019une modification du microbiote, se produisent spontan\u00e9ment, am\u00e9liorant l\u2019absorption intestinale et diminuant la d\u00e9pendance \u00e0 la nutrition parent\u00e9rale. Cet article r\u00e9sume les principales cons\u00e9quences physiopathologiques (b\u00e9n\u00e9fiques ou d\u00e9l\u00e9t\u00e8res) d\u2019une r\u00e9section \u00e9tendue de l\u2019intestin gr\u00eale et la prise en charge nutritionnelle et m\u00e9dicamenteuse du syndrome de gr\u00eale court chez l\u2019adulte.<\/jats:p>","DOI":"10.1051\/medsci\/2021110","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T07:59:41Z","timestamp":1631001581000},"page":"742-751","source":"Crossref","is-referenced-by-count":6,"title":["Le syndrome de gr\u00eale court chez l\u2019adulte"],"prefix":"10.1051","volume":"37","author":[{"given":"Brune","family":"de 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