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Si la balance b\u00e9n\u00e9fices-risques est, pour la tr\u00e8s grande majorit\u00e9 des femmes, tr\u00e8s favorable, son utilisation doit \u00eatre extr\u00eamement prudente dans certaines situations cliniques et, en particulier, chez les femmes \u00e0 risque vasculaire. Il est donc indispensable de renseigner l\u2019ensemble des facteurs de risque vasculaire avant toute prescription de COP, quelle que soit sa voie d\u2019administration. D\u2019un point de vue carcinologique, si l\u2019utilisation de la COP est associ\u00e9e \u00e0 une discr\u00e8te augmentation du risque de cancer du sein, les b\u00e9n\u00e9fices m\u00e9connus, persistant de nombreuses ann\u00e9es apr\u00e8s son arr\u00eat, vis-\u00e0-vis du risque de cancer de l\u2019ovaire et de l\u2019endom\u00e8tre, contrebalancent largement ce risque mammaire. Enfin, la COP apporte des avantages non contraceptifs, notamment dans les situations cliniques telles que les dysm\u00e9norrh\u00e9es ou l\u2019endom\u00e9triose invalidante, am\u00e9liorant profond\u00e9ment la qualit\u00e9 de vie des femmes. Il est donc n\u00e9cessaire d\u2019\u00e9valuer tr\u00e8s pr\u00e9cis\u00e9ment le contexte clinique de chaque femme afin d\u2019adapter la meilleure strat\u00e9gie contraceptive en minimisant les risques et pour b\u00e9n\u00e9ficier des avantages potentiels.<\/jats:p>","DOI":"10.1051\/medsci\/2021238","type":"journal-article","created":{"date-parts":[[2022,1,21]],"date-time":"2022-01-21T04:01:22Z","timestamp":1642737682000},"page":"59-69","source":"Crossref","is-referenced-by-count":5,"title":["La balance b\u00e9n\u00e9fices-risques des contraceptions hormonales estroprogestatives"],"prefix":"10.1051","volume":"38","author":[{"given":"Genevi\u00e8ve","family":"Plu-Bureau","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Raccah-Tebeka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2022,1,21]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1136\/bmj.323.7305.131","volume":"323","author":"Kemmeren","year":"2001","journal-title":"BMJ"},{"key":"R2","first-page":"7","volume":"17","author":"Martinez","year":"2012","journal-title":"Health Care"},{"issue":"1","key":"R3","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.beem.2012.11.002","volume":"27","author":"Plu-Bureau","year":"2013","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"R4","doi-asserted-by":"crossref","first-page":"f5298","DOI":"10.1136\/bmj.f5298","volume":"347","author":"Stegeman","year":"2013","journal-title":"BMJ"},{"key":"R5","first-page":"CD01081","volume":"3","author":"de Bastos","year":"2014","journal-title":"Cochrane Database Syst Rev"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Dragoman MV, Tepper NK, Fu R, et al. 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