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Cependant, le taux d\u2019\u00e9chec \u00e0 chaque cycle est \u00e9valu\u00e9 \u00e0 environ 75 %. Il est donc n\u00e9cessaire de mieux comprendre le d\u00e9veloppement embryonnaire humain afin d\u2019am\u00e9liorer le taux de succ\u00e8s des FIV. Les mod\u00e8les d\u2019\u00e9tude ont beaucoup \u00e9volu\u00e9 ces derni\u00e8res ann\u00e9es : mise au point de la culture embryonnaire, s\u00e9quen\u00e7age du transcriptome de cellules individualis\u00e9es, d\u00e9couverte des conditions de culture de cellules souches pluripotentes na\u00efves et g\u00e9n\u00e9ration de blasto\u00efdes. 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