{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T22:29:40Z","timestamp":1744237780024},"reference-count":45,"publisher":"EDP Sciences","issue":"3","license":[{"start":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T00:00:00Z","timestamp":1679356800000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:p>Au cours des trente derni\u00e8res ann\u00e9es, des progr\u00e8s majeurs ont \u00e9t\u00e9 r\u00e9alis\u00e9s dans la prise en charge des enfants souffrant d\u2019une maladie r\u00e9nale chronique (MRC). Cependant, les donn\u00e9es \u00e9pid\u00e9miologiques existantes proviennent essentiellement des registres de traitement de suppl\u00e9ance de l\u2019insuffisance r\u00e9nale terminale. L\u2019incidence et la pr\u00e9valence aux stades plus pr\u00e9coces de MRC restent donc mal connues, mais de rares \u00e9tudes en population sugg\u00e8rent que la pr\u00e9valence de la MRC, tous stades confondus, pourrait concerner jusqu\u2019\u00e0 1 % de la population p\u00e9diatrique. Les d\u00e9sordres cong\u00e9nitaux, incluant les hypodysplasies r\u00e9nales et uropathies malformatives (CAKUT) et les n\u00e9phropathies h\u00e9r\u00e9ditaires, sont responsables de la moiti\u00e9 aux deux tiers des cas de MRC de l\u2019enfant dans les pays industrialis\u00e9s, alors que les n\u00e9phropathies acquises pr\u00e9dominent dans les pays en d\u00e9veloppement. La progression de la MRC est plus lente chez les enfants avec une maladie cong\u00e9nitale que chez ceux ayant une n\u00e9phropathie glom\u00e9rulaire, et d\u2019autres facteurs de risque de progression ont \u00e9galement \u00e9t\u00e9 identifi\u00e9s. Alors que la survie des enfants pr\u00e9sentant une MRC s\u2019est continuellement am\u00e9lior\u00e9e au cours du temps, la mortalit\u00e9 reste 20 \u00e0 30 fois sup\u00e9rieure \u00e0 celle de la population g\u00e9n\u00e9rale p\u00e9diatrique.<\/jats:p>","DOI":"10.1051\/medsci\/2023027","type":"journal-article","created":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T09:02:31Z","timestamp":1679389351000},"page":"209-218","source":"Crossref","is-referenced-by-count":2,"title":["\u00c9pid\u00e9miologie des maladies r\u00e9nales chroniques en p\u00e9diatrie"],"prefix":"10.1051","volume":"39","author":[{"given":"J\u00e9r\u00f4me","family":"Harambat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Morin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"250","published-online":{"date-parts":[[2023,3,21]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"ii121","DOI":"10.1093\/ndt\/gfw330","volume":"32","author":"Jager","year":"2017","journal-title":"Nephrol Dial Transplant"},{"key":"R2","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s00467-011-1939-1","volume":"27","author":"Harambat","year":"2012","journal-title":"Pediatr Nephrol"},{"key":"R3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00467-017-3681-9","volume":"33","author":"Chesnaye","year":"2018","journal-title":"Pediatr Nephrol"},{"key":"R4","doi-asserted-by":"crossref","first-page":"e382","DOI":"10.1542\/peds.111.4.e382","volume":"111","author":"Ardissino","year":"2003","journal-title":"Pediatrics"},{"key":"R5","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1007\/s004670050462","volume":"12","author":"Fivush","year":"1998","journal-title":"Pediatr Nephrol"},{"key":"R6","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1007\/BF00856534","volume":"8","author":"Deleau","year":"1994","journal-title":"Pediatr Nephrol"},{"key":"R7","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1007\/s00467-005-2000-z","volume":"20","author":"Al-Eisa","year":"2005","journal-title":"Pediatr Nephrol"},{"key":"R8","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1542\/peds.111.6.1416","volume":"111","author":"Hogg","year":"2003","journal-title":"Pediatrics"},{"issue":"3","key":"R9","first-page":"1","volume":"2013","author":"Kdigo, CKD Work Group","year":"2012","journal-title":"Kidney Int"},{"key":"R10","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1681\/ASN.2008030287","volume":"20","author":"Schwartz","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"R11","doi-asserted-by":"crossref","first-page":"1978","DOI":"10.1093\/ndt\/gfr556","volume":"27","author":"Peco-Antic","year":"2012","journal-title":"Nephrol Dial Transplant"},{"key":"R12","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00467-009-1424-2","volume":"25","author":"Mong Hiep","year":"2010","journal-title":"Pediatr Nephrol"},{"key":"R13","first-page":"508","volume":"30","author":"Areses Trapote","year":"2010","journal-title":"Nefrologia"},{"key":"R14","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1136\/archdischild-2012-302400","volume":"98","author":"Kim","year":"2013","journal-title":"Arch Dis Child"},{"key":"R15","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1093\/ndt\/gfs611","volume":"28","author":"Ishikura","year":"2013","journal-title":"Nephrol Dial Transplant"},{"key":"R16","unstructured":"The North American Pediatric Renal Trials and Collaborative Studies 2010 Annual Report. www.naprtcs.org2010."},{"key":"R17","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s00467-008-0998-4","volume":"24","author":"Bek","year":"2009","journal-title":"Pediatr Nephrol"},{"key":"R18","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/pr.2014.189","volume":"77","author":"Kayange","year":"2015","journal-title":"Pediatr Res"},{"key":"R19","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1053\/j.ajkd.2015.01.008","volume":"65","author":"Warady","year":"2015","journal-title":"Am J Kidney Dis"},{"key":"R20","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s00467-020-04595-3","volume":"36","author":"Leibler","year":"2021","journal-title":"Pediatr Nephrol"},{"key":"R21","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.ekir.2019.02.014","volume":"4","author":"Al Riyami","year":"2019","journal-title":"Kidney Int Rep"},{"key":"R22","first-page":"438","volume":"11","author":"Esbjorner","year":"1997","journal-title":"Swedish Pediatric Nephrology Association. 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