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Pourtant, il n\u2019existe \u00e0 ce jour aucun vaccin valid\u00e9 pour une utilisation dans l\u2019esp\u00e8ce humaine pour lutter contre ces ar\u00e9navirus. Dans cette synth\u00e8se, nous pr\u00e9sentons les diff\u00e9rents ar\u00e9navirus causant des maladies mortelles chez l\u2019esp\u00e8ce humaine et les principaux candidats vaccins d\u00e9velopp\u00e9s au cours des derni\u00e8res d\u00e9cennies contre ces virus. Nous d\u00e9crivons plus particuli\u00e8rement le vaccin rougeole-Lassa, premier vaccin contre la fi\u00e8vre de Lassa \u00e0 avoir \u00e9t\u00e9 test\u00e9 dans l\u2019esp\u00e8ce humaine, et la plateforme MOPEVAC qui permet de g\u00e9n\u00e9rer avec succ\u00e8s des vaccins mono- ou multivalents contre potentiellement tous les ar\u00e9navirus pathog\u00e8nes connus.<\/jats:p>","DOI":"10.1051\/medsci\/2023162","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T09:05:48Z","timestamp":1701248748000},"page":"855-861","source":"Crossref","is-referenced-by-count":0,"title":["Les fi\u00e8vres h\u00e9morragiques caus\u00e9es par les ar\u00e9navirus : de r\u00e9centes avanc\u00e9es vaccinales"],"prefix":"10.1051","volume":"39","author":[{"given":"Mathieu","family":"Mateo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvain","family":"Baize","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"250","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"R1","first-page":"265","volume":"439","author":"Sironi","year":"2023","journal-title":"Cur Top Microbiol Immunol"},{"key":"R2","unstructured":"Buchmeier MJ, de la Torre JC, and Peters CJ. 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