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Leur pr\u00e9valence \u00e9lev\u00e9e, leur fort retentissement sur la qualit\u00e9 de vie individuelle et leur impact \u00e9conomique et soci\u00e9tal important justifient une \u00e9tude sp\u00e9cifique. Parmi ces douleurs, les douleurs neuropathiques, r\u00e9sultant d\u2019une maladie ou d\u2019un traumatisme du syst\u00e8me nerveux trig\u00e9minal, sont parmi les plus difficiles \u00e0 diagnostiquer et \u00e0 soigner. L\u2019\u00e9tude des m\u00e9canismes neurobiologiques, p\u00e9riph\u00e9riques et centraux les sous-tendant a permis de nombreuses avanc\u00e9es conceptuelles, cliniques et th\u00e9rapeutiques, avec, par exemple, la mise en \u00e9vidence du r\u00f4le des cellules nerveuses et non nerveuses, telles que la glie, les immunocytes, les cellules endoth\u00e9liales vasculaires ou le r\u00f4le de la reconfiguration de la circuiterie nerveuse au niveau du complexe sensitif trig\u00e9minal, dans la gen\u00e8se des douleurs neuropathiques post-l\u00e9sionnelles. Les interactions cellulaires au sein du ganglion trig\u00e9minal, susceptibles d\u2019\u00e9clairer la compr\u00e9hension de certaines comorbidit\u00e9s douloureuses dentaires, oculaires ou c\u00e9phalalgiques, sont \u00e9galement d\u00e9crites.<\/jats:p>","DOI":"10.1051\/medsci\/2023197","type":"journal-article","created":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T09:03:15Z","timestamp":1706778195000},"page":"64-71","source":"Crossref","is-referenced-by-count":0,"title":["Sp\u00e9cificit\u00e9s de la douleur neuropathique oro-faciale"],"prefix":"10.1051","volume":"40","author":[{"given":"Nathan","family":"Moreau","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e9dric","family":"Peirs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radhouane","family":"Dallel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Boucher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"250","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"R1","unstructured":"Moreau N, Boucher Y. 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