{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T08:56:54Z","timestamp":1763542614035,"version":"3.45.0"},"reference-count":8,"publisher":"EDP Sciences","issue":"10","license":[{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"vor","delay-in-days":49,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>La sp\u00e9cialit\u00e9 G\u00e9nie Biologique de Polytech Nice Sophia (Universit\u00e9 C\u00f4te d\u2019Azur) forme des ing\u00e9nieurs polyvalents dans les domaines de la pharmacologie, la toxicologie et la bio-informatique, capables de conduire des projets relatifs aux biotechnologies et aux bio-industries. Les ing\u00e9nieurs en G\u00e9nie Biologique seront capables de r\u00e9pondre aux changements soci\u00e9taux impliquant \u00e0 la fois :<\/jats:p>\n                  <jats:p>\n                    <jats:list list-type=\"bullet\">\n                      <jats:list-item>\n                        <jats:p>Une meilleure ma\u00eetrise et gestion des risques toxicologiques environnementaux (r\u00e8glementations et normes) et en sant\u00e9 humaine ;<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>L\u2019approche One Health ;<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>La sant\u00e9 (vieillissement, bien-\u00eatre, maladies infectieuses et exposome) ;<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:p>La gestion des ressources (gestion durable, \u00e9co et biotechnologie) pour accompagner la transition \u00e9cologique.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>\n                  <jats:p>Dans le module Biotech Success Stories en derni\u00e8re ann\u00e9e (grade Master 2), les \u00e9tudiants suivent le d\u00e9veloppement rapide des technologies, d\u00e9cryptent les strat\u00e9gies innovantes en recherche m\u00e9dicale et s\u2019exercent \u00e0 l\u2019\u00e9criture sous la supervision de chercheurs du Centre M\u00e9diterran\u00e9en de M\u00e9decine Mol\u00e9culaire de Nice.<\/jats:p>\n                  <jats:p>\n                    <jats:list list-type=\"label\">\n                      <jats:list-item>\n                        <jats:label>1)<\/jats:label>\n                        <jats:p>Comment l\u2019IA peut repousser les fronti\u00e8res de la r\u00e9sistance aux antibiotiques, c\u2019est le sujet pilot\u00e9 par Juan A. Garcia-Sanchez, dont la recherche est centr\u00e9e sur la d\u00e9couverte et d\u00e9veloppement de nouvelles th\u00e9rapies antimicrobiennes.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:label>2)<\/jats:label>\n                        <jats:p>Combiner \u00e9pig\u00e9n\u00e9tique et immunoth\u00e9rapie pour le traitement de la leuc\u00e9mie my\u00e9lo\u00efde aigu\u00eb, ce projet est pilot\u00e9 par Pilar M. Dominguez, directrice de l\u2019\u00e9quipe EPIg\u00e9n\u00e9tique du Cancer et iMMunoth\u00e9rapies (CEPIMMY), dont la recherche est centr\u00e9e sur les m\u00e9canismes \u00e9pig\u00e9n\u00e9tiques dans le cancer du sang.<\/jats:p>\n                      <\/jats:list-item>\n                      <jats:list-item>\n                        <jats:label>3)<\/jats:label>\n                        <jats:p>Induire la mitophagie et cibler son potentiel th\u00e9rapeutique dans le cancer, ce projet est pilot\u00e9 par Thomas Botton, dont la recherche est d\u00e9di\u00e9e \u00e0 l\u2019identification de nouveaux compos\u00e9s bioactifs dans la lutte contre le m\u00e9lanome.<\/jats:p>\n                      <\/jats:list-item>\n                    <\/jats:list>\n                  <\/jats:p>","DOI":"10.1051\/medsci\/2025144","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T08:52:04Z","timestamp":1763542324000},"page":"798-801","source":"Crossref","is-referenced-by-count":0,"title":["Combiner \u00e9pig\u00e9n\u00e9tique et immunoth\u00e9rapie"],"prefix":"10.1051","volume":"41","author":[{"given":"Nicole","family":"Ballan","sequence":"first","affiliation":[{"name":"Dipl\u00f4me d\u2019ing\u00e9nieur Polytech Nice Sophia en g\u00e9nie biologique, sp\u00e9cialit\u00e9 pharmacologie et biotechnologies, Universit\u00e9 C\u00f4t\u00e9 d\u2019Azur","place":["France"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7032-1880","authenticated-orcid":false,"given":"Melvin","family":"Bordji","sequence":"additional","affiliation":[{"name":"Dipl\u00f4me d\u2019ing\u00e9nieur Polytech Nice Sophia en g\u00e9nie biologique, sp\u00e9cialit\u00e9 pharmacologie et biotechnologies, Universit\u00e9 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