{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:57:02Z","timestamp":1764320222325,"version":"3.46.0"},"reference-count":15,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/www.edpsciences.org\/en\/authors\/copyright-and-licensing"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci (Paris)"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>Les exosquelettes des membres inf\u00e9rieurs repr\u00e9sentent une innovation prometteuse pour assister la marche et les transferts dans les maladies neuromusculaires (MNM). Toutefois, leurs effets r\u00e9els sur la marche des personnes atteintes de MNM demeurent encore largement inconnus car les dispositifs existants reposent sur des algorithmes d\u2019assistance dont la pertinence face aux strat\u00e9gies compensatoires propres \u00e0 ces pathologies reste \u00e0 d\u00e9montrer. Dans le cadre de notre programme de recherche, nous avons men\u00e9 une analyse multiparam\u00e9trique int\u00e9grant des donn\u00e9es cin\u00e9matiques, \u00e9lectromyographiques, de force musculaire et des perceptions subjectives. Nos r\u00e9sultats montrent d\u2019une part que, compar\u00e9s \u00e0 des sujets sains, les patients atteints de MNM pr\u00e9sentent une baisse de performance \u00e0 la marche qui est associ\u00e9e \u00e0 une r\u00e9duction de la cadence, une augmentation de la dur\u00e9e d\u2019appui, une diminution de la longueur du pas, un angle r\u00e9duit de cheville au d\u00e9but du cycle, une faible force musculaire et une variabilit\u00e9 accrue de la cin\u00e9matique. D\u2019autre part, l\u2019\u00e9valuation de deux exosquelettes commerciaux (Keeogo\u00ae et Myosuit) a r\u00e9v\u00e9l\u00e9, malgr\u00e9 une utilisation s\u00e9curitaire, une baisse de performance au test de marche par rapport \u00e0 celle \u00e9valu\u00e9e sans ces dispositifs, li\u00e9e \u00e0 des redistributions complexes de l\u2019activit\u00e9 musculaire. Les d\u00e9terminants cl\u00e9s restent similaires avec ou sans assistance, soulignant les limites des dispositifs actuels. Les perspectives incluent le d\u00e9veloppement de mod\u00e8les musculosquelettiques individualis\u00e9s, permettant d\u2019optimiser l\u2019assistance vers une personnalisation optimis\u00e9e.<\/jats:p>","DOI":"10.1051\/medsci\/2025174","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T08:52:58Z","timestamp":1764319978000},"page":"23-27","source":"Crossref","is-referenced-by-count":0,"special_numbering":"Hors s\u00e9rie n\u00b0 2","title":["Identifier et mod\u00e9liser les d\u00e9terminants de la marche dans les maladies neuromusculaires pour optimiser l\u2019assistance de la fonction dans la vie quotidienne"],"prefix":"10.1051","volume":"41","author":[{"given":"Romain","family":"Feigean","sequence":"first","affiliation":[{"name":"Laboratoire de Physiologie et d\u2019\u00c9valuation Neuromusculaire, Centre d\u2019\u00e9valuation et d\u2019exploration neuromusculaire, Institut de 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