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Cette revue pr\u00e9sente trois strat\u00e9gies de repositionnement, illustr\u00e9es par des mol\u00e9cules th\u00e9rapeutiques, parmi lesquelles la fluox\u00e9tine (Prozac\n                    <jats:sup>\u00ae<\/jats:sup>\n                    ), un antid\u00e9presseur inhibant la recapture de la s\u00e9rotonine et pr\u00e9sentant \u00e9galement plusieurs propri\u00e9t\u00e9s antivirales. L\u2019ensemble des exemples d\u00e9crits dans cette revue souligne \u00e0 la fois le potentiel du repositionnement de m\u00e9dicaments et ses limites, notamment dans une approche \u00ab\u00a0cl\u00e9 en main\u00a0\u00bb.\n                  <\/jats:p>","DOI":"10.1051\/medsci\/2026123","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T11:45:38Z","timestamp":1789386338000},"page":"691-700","source":"Crossref","is-referenced-by-count":0,"title":["La reconversion th\u00e9rapeutique de m\u00e9dicaments pour traiter les maladies infectieuses virales"],"prefix":"10.1051","volume":"42","author":[{"given":"Marine O.","family":"Faucher","sequence":"first","affiliation":[{"name":"Unit\u00e9 des virus \u00e9mergents (UVE), Aix-Marseille Universit\u00e9, Universit\u00e0 di Corsica, IRD 190, Inserm U1207","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Barral","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, CNRS, ICR","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Coutard","sequence":"additional","affiliation":[{"name":"Unit\u00e9 des virus \u00e9mergents (UVE), Aix-Marseille Universit\u00e9, Universit\u00e0 di Corsica, IRD 190, Inserm U1207","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2026,9,14]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1051\/medsci\/2019047","volume":"35","author":"Duguet","year":"2019","journal-title":"Med Sci (Paris)"},{"key":"R2","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1111\/j.1476-5381.2010.01127.x","volume":"162","author":"Hughes","year":"2011","journal-title":"British J Pharmacol"},{"key":"R3","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1051\/medsci\/20143012019","volume":"30","author":"Rognan","year":"2014","journal-title":"Med Sci (Paris)"},{"key":"R4","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/s41597-023-01984-9","volume":"10","author":"Rogers","year":"2023","journal-title":"Sci Data"},{"key":"R5","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.coph.2009.08.004","volume":"9","author":"Mayr","year":"2009","journal-title":"Current Op Pharmacol"},{"key":"R6","doi-asserted-by":"crossref","first-page":"531","DOI":"10.3389\/fimmu.2019.00531","volume":"10","author":"Pizzorno","year":"2019","journal-title":"Front Immunol"},{"key":"R7","doi-asserted-by":"crossref","first-page":"13596535221082773","DOI":"10.1177\/13596535221082773","volume":"27","author":"Cihlar","year":"2022","journal-title":"Antivir Ther"},{"key":"R8","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.antiviral.2018.03.003","volume":"153","author":"Delang","year":"2018","journal-title":"Antivir Res"},{"key":"R9","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s12026-011-8263-5","volume":"52","author":"Gallay","year":"2012","journal-title":"Immunol Res"},{"key":"R10","doi-asserted-by":"publisher","unstructured":"Reddy AS, Zhang S. 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