{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T09:37:24Z","timestamp":1790501844481,"version":"4.1.0"},"reference-count":18,"publisher":"JLE","issue":"2","license":[{"start":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T00:00:00Z","timestamp":1561507200000},"content-version":"vor","delay-in-days":25,"URL":"https:\/\/www.edpsciences.org\/en\/authors\/copyright-and-licensing"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orthod Fr"],"accepted":{"date-parts":[[2019,5,10]]},"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p><jats:bold>Introduction\u00a0:<\/jats:bold>\u00a0Les d\u00e9fauts primaires d\u2019\u00e9ruption (DPE) correspondent \u00e0 l\u2019\u00e9chec partiel ou total d\u2019\u00e9ruption d\u2019une ou de plusieurs dents, sans obstacle m\u00e9canique; des formes isol\u00e9es et syndromiques de cette pathologie existent. Ils r\u00e9sultent d\u2019une anomalie des processus d\u2019\u00e9ruption qui peut toucher les dents temporaires et\/ou les dents permanentes. Les molaires sont les principales dents atteintes, provoquant des infraclusions post\u00e9rieures. Pathologie rare, les DPE sont essentiellement pris en charge par les sp\u00e9cialistes en orthop\u00e9die dento-faciale (ODF). Les tentatives de traction chirurgico-orthodontiques se soldent g\u00e9n\u00e9ralement par un \u00e9chec. <jats:bold>Mat\u00e9riels et m\u00e9thodes\u00a0:<\/jats:bold>\u00a0Le but de ce travail \u00e9tait d\u2019\u00e9valuer, par une enqu\u00eate prospective bas\u00e9e sur un questionnaire anonyme, les connaissances des orthodontistes et la complexit\u00e9 de la prise en charge de cette anomalie de l\u2019\u00e9ruption. Les praticiens des r\u00e9gions Grand Est et Bourgogne-Franche-Comt\u00e9 ont \u00e9t\u00e9 sollicit\u00e9s. <jats:bold>R\u00e9sultats\u00a0:<\/jats:bold>\u00a0Le taux de participation \u00e9tait de 33,5\u00a0%. Les participants ont principalement obtenu leur qualification entre\u00a01980 et\u00a02009 (80\u00a0%), via le Certificat d\u2019\u00c9tudes Cliniques Sp\u00e9cialis\u00e9es Mention Orthodontie (CECSMO) (87\u00a0%). Quatre-vingt-six pour cent d\u2019entre eux connaissaient les DPE mais 20\u00a0% seulement l\u2019implication possible du g\u00e8ne <jats:italic>PTHR1 (Parathyroid Hormone Receptor\u00a01)<\/jats:italic>. Le vaste panel de th\u00e9rapeutiques envisag\u00e9es et les faibles taux de satisfaction soulignent les difficult\u00e9s rencontr\u00e9es par les praticiens. <jats:bold>Discussion\u00a0:<\/jats:bold>\u00a0La variabilit\u00e9 ph\u00e9notypique complique le diagnostic et rend difficile toute syst\u00e9matisation de la prise en charge. <jats:bold>Conclusion\u00a0:<\/jats:bold>\u00a0De nouveaux projets de recherche clinique, notamment en mati\u00e8re de diagnostic mol\u00e9culaire, am\u00e9lioreront les connaissances sur les corr\u00e9lations g\u00e9notype-ph\u00e9notype, et conditionneront \u00e9ventuellement la prise en charge th\u00e9rapeutique.<\/jats:p>","DOI":"10.1051\/orthodfr\/2019013","type":"journal-article","created":{"date-parts":[[2019,6,26]],"date-time":"2019-06-26T08:28:41Z","timestamp":1561537721000},"page":"149-159","source":"Crossref","is-referenced-by-count":3,"title":["D\u00e9fauts primaires d\u2019\u00e9ruption : \u00e9tat des lieux aupr\u00e8s\u00a0des\u00a0sp\u00e9cialistes en orthop\u00e9die dento-faciale des\u00a0r\u00e9gions Grand\u00a0Est et Bourgogne-Franche-Comt\u00e9"],"prefix":"10.1684","volume":"90","author":[{"given":"Marion","family":"Strub","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elie","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-C\u00e9cile","family":"Mani\u00e8re","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"18929","published-online":{"date-parts":[[2019,6,26]]},"reference":[{"issue":"4","key":"R1","first-page":"ZD14","volume":"8","author":"Aruna","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"R2","unstructured":"Bloch-Zupan A, Rey T, Laugel-Haushalter V, Jung S, Clauss F, Strub M, et al. 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