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Metallopeptidases from parasitic protozoa, including\n                    <jats:italic>Toxoplasma<\/jats:italic>\n                    , are investigated because of their crucial role in parasite biology. In the present study, we screened the\n                    <jats:italic>T. gondii<\/jats:italic>\n                    database using PFAM motifs specific for metallopeptidases in association with the MEROPS peptidase Database (release\u200910.0). In all, 49\u2009genes\u00a0encoding proteins with metallopeptidase signatures were identified in the\n                    <jats:italic>Toxoplasma<\/jats:italic>\n                    genome. An Interpro Search enabled us to uncover their domain\/motif organization, and orthologs with the highest similarity by BLAST were used for annotation. These 49\u2009\n                    <jats:italic>Toxoplasma<\/jats:italic>\n                    metallopeptidases clustered into 15\u2009families described in the MEROPS database. Experimental expression analysis of their genes in the tachyzoite stage revealed transcription for all genes studied. Further research on the role of these peptidases should increase our knowledge of basic\n                    <jats:italic>Toxoplasma<\/jats:italic>\n                    biology and provide opportunities to identify novel therapeutic targets. This type of study would also open a path towards the comparative biology of apicomplexans.\n                  <\/jats:p>","DOI":"10.1051\/parasite\/2018025","type":"journal-article","created":{"date-parts":[[2018,5,8]],"date-time":"2018-05-08T04:10:20Z","timestamp":1525752620000},"page":"26","source":"Crossref","is-referenced-by-count":29,"title":["Metallopeptidases of\n                    <i>Toxoplasma gondii<\/i>\n                    :\n                    <i>in silico<\/i>\n                    identification and gene expression"],"prefix":"10.1051","volume":"25","author":[{"given":"Sandie","family":"Escotte-Binet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Huguenin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Aubert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Pascaline","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Kaltenbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Florent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Villena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2018,5,8]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0031182002001828","volume":"125","author":"Allary","year":"2002","journal-title":"Parasitology"},{"key":"R2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpddr.2011.12.001","volume":"2","author":"Aminake","year":"2012","journal-title":"International Journal for Parasitology. 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