{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T16:53:08Z","timestamp":1788886388695,"version":"build-2803163510"},"reference-count":48,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T00:00:00Z","timestamp":1527465600000},"content-version":"vor","delay-in-days":147,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite"],"accepted":{"date-parts":[[2018,4,21]]},"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>Initial investigations suggested the existence of two distinct genotypes of<jats:italic>Dipylidium caninum<\/jats:italic>from infected cat fleas (<jats:italic>Ctenocephalides felis<\/jats:italic>). One genotype was found almost always (&gt;\u200995%) in fleas collected from, and proglottids shed by, domestic dogs. The other was found almost always (&gt;\u200995%) in fleas collected from, and proglottids shed by, domestic cats. Molecular investigations (Part 1, in this journal) confirmed the presence of two distinct genotypes. Due to the apparent host association observed, these were referred to as the \u201c<jats:italic>D. caninum<\/jats:italic>canine genotype\u201d and the \u201c<jats:italic>D. caninum<\/jats:italic>feline genotype\u201d. The current article reports on an<jats:italic>in vivo<\/jats:italic>experimental infection study assessing the host-parasite interaction for each genotype. Mixed infections with the two genotypes in both dogs and cats were conducted. The specific genotyping of proglottids allowed us to assess the specific prepatent periods, prolificity, and longevity of each genotype in dogs<jats:italic>versus<\/jats:italic>cats. The possible hybridisation was also studied through molecular evaluation of the proglottids expelled by infected dogs and cats. Results demonstrate a clear distinct host interaction. The canine<jats:italic>D. caninum<\/jats:italic>genotype occurred at a higher frequency in dogs, with a shorter prepatent period and a longer lifespan; and the feline genotype occurred at a higher frequency in cats, with a shorter prepatent period and a longer lifespan. The absence of any hybrids in the mixed infections of both dogs and cats confirm the hypothesis of two distinct genotypes, suggesting the possibility of two distinct species within<jats:italic>Dipylidium caninum<\/jats:italic>.<\/jats:p>","DOI":"10.1051\/parasite\/2018029","type":"journal-article","created":{"date-parts":[[2018,5,28]],"date-time":"2018-05-28T07:59:55Z","timestamp":1527494395000},"page":"31","source":"Crossref","is-referenced-by-count":43,"title":["Analysis of<i>Dipylidium caninum<\/i>tapeworms from dogs and cats, or their respective fleas"],"prefix":"10.1051","volume":"25","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Beugnet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Labuschagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christa de","family":"Vos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dionne","family":"Crafford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josephus","family":"Fourie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2018,5,28]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.vetpar.2011.09.004","volume":"184","author":"Abdybekova","year":"2012","journal-title":"Veterinary Parasitology"},{"issue":"6","key":"R2","first-page":"37","volume":"2","author":"Adam","year":"2012","journal-title":"Al Neelain Medical Journal"},{"key":"R3","first-page":"144","volume":"2","author":"Al-Sabi","year":"2013","journal-title":"International Journal for Parasitology: Parasites and Wildlife"},{"key":"R4","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0167-5877(95)00527-7","volume":"27","author":"Anene","year":"1996","journal-title":"Preventive Veterinary Medicine"},{"key":"R5","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.vetpar.2005.12.021","volume":"137","author":"Beck","year":"2006","journal-title":"Veterinary Parasitology"},{"key":"R6","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.prevetmed.2012.09.009","volume":"109","author":"Beiromvand","year":"2013","journal-title":"Preventive Veterinary Medicine,"},{"key":"R7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1051\/parasite\/2013006","volume":"20","author":"Beugnet","year":"2013","journal-title":"Parasite"},{"key":"R8","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/j.vetpar.2014.06.008","volume":"205","author":"Beugnet","year":"2014","journal-title":"Veterinary Parasitology"},{"key":"R9","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.prevetmed.2011.04.015","volume":"100","author":"Bwalya","year":"2011","journal-title":"Preventive Veterinary Medicine"},{"key":"R10","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0020-7519(95)00082-8","volume":"26","author":"Cabrera","year":"1996","journal-title":"International Journal for Parasitology"},{"key":"R11","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0304-4017(97)00182-9","volume":"75","author":"Calvete","year":"1998","journal-title":"Veterinary Parasitology"},{"key":"R12","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.vetpar.2016.12.017","volume":"234","author":"Chandra","year":"2017","journal-title":"Veterinary Parasitology"},{"key":"R13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.vetpar.2008.11.002","volume":"160","author":"Dai","year":"2009","journal-title":"Veterinary Parasitology"},{"key":"R14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.vetpar.2006.06.024","volume":"142","author":"Dalimi","year":"2006","journal-title":"Veterinary Parasitology"},{"key":"R15","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.vetpar.2006.11.006","volume":"145","author":"Dubn\u00e1","year":"2007","journal-title":"Veterinary Parasitology"},{"key":"R16","first-page":"165","volume":"2","author":"Dybing","year":"2013","journal-title":"International Journal for Parasitology: Parasites and Wildlife"},{"key":"R17","first-page":"257","volume":"2","author":"East","year":"2013","journal-title":"International Journal for Parasitology: Parasites and Wildlife"},{"key":"R18","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.vetpar.2004.10.004","volume":"127","author":"Egu\u00eda-Aguilar","year":"2005","journal-title":"Veterinary Parasitology"},{"key":"R19","first-page":"104","volume":"8","author":"El-Seify","year":"2017","journal-title":"Veterinary Parasitology: Regional Studies and Reports"},{"key":"R20","unstructured":"Euz\u00e9by J. 1966. 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