{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T22:30:27Z","timestamp":1789252227677,"version":"build-2803163510"},"reference-count":62,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2018,7,23]],"date-time":"2018-07-23T00:00:00Z","timestamp":1532304000000},"content-version":"vor","delay-in-days":203,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite"],"accepted":{"date-parts":[[2018,6,23]]},"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>\n\t\t\t\t\t<jats:italic>Toxoplasma gondii<\/jats:italic> transmitted from blood donors to receiving patients has become a concern as numerous articles about the epidemiology of <jats:italic>T. gondii<\/jats:italic> infection in blood donors from different provinces have been published in China. This study aimed to evaluate the seroprevalence of <jats:italic>T. gondii<\/jats:italic> infection in Chinese blood donors using a meta-analysis. A total of 40 eligible studies, published from 1986 to 2017 and covering 18 provinces and municipalities were included. Among a total of 49,784 Chinese blood donors, the overall IgG seroprevalence of <jats:italic>T. gondii<\/jats:italic> infection was 6.26% (95% CI: 4.62%\u20138.13%). The highest prevalence was in the Northeast of China and the lowest in Central China. The infection rate increased slowly over the years, but not significantly. A statistically significant correlation was found between the seroprevalence of <jats:italic>T. gondii<\/jats:italic> infection and the detection method and educational level (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.01). There was no relationship between age, gender, occupation and blood type and seroprevalence of <jats:italic>T. gondii<\/jats:italic> (<jats:italic>p<\/jats:italic>\u00a0&gt;\u00a00.05). The prevalence of antibodies to <jats:italic>T. gondii<\/jats:italic> in Chinese blood donors was lower than in other countries, but the risk of transfusion-transmitted toxoplasmosis still exits. More concise methods are still needed to evaluate the possibility of transfusion-transmitted toxoplasmosis from blood donors.<\/jats:p>","DOI":"10.1051\/parasite\/2018037","type":"journal-article","created":{"date-parts":[[2018,7,24]],"date-time":"2018-07-24T07:54:40Z","timestamp":1532418880000},"page":"36","source":"Crossref","is-referenced-by-count":26,"title":["Seroprevalence of <i>Toxoplasma gondii<\/i> infection in blood donors in mainland China: a systematic review and meta-analysis"],"prefix":"10.1051","volume":"25","author":[{"given":"Taiwu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifang","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuanqin","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengzhong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2018,7,23]]},"reference":[{"key":"R1","first-page":"884","volume":"36","author":"Ai","year":"2007","journal-title":"Shanxi Medical Journal"},{"issue":"11","key":"R2","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1136\/jech-2013-203104","volume":"67","author":"Barendregt","year":"2013","journal-title":"Journal of Epidemiology Community Health"},{"key":"R3","first-page":"37","volume":"7","author":"Chen","year":"1991","journal-title":"Chinese Journal of Zoonoses"},{"key":"R4","first-page":"243","volume":"24","author":"Chen","year":"1999","journal-title":"Journal of Guiyang Medical College"},{"issue":"4","key":"R5","first-page":"2","volume":"14","author":"Chen","year":"1998","journal-title":"Chinese Journal of Zoonoses"},{"issue":"7109","key":"R6","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1136\/bmj.315.7109.629","volume":"315","author":"Egger","year":"1997","journal-title":"British Medical Journal"},{"key":"R7","first-page":"3","volume":"13","author":"Feng","year":"1998","journal-title":"Shanxi Journal of Medical Laboratory Sciences"},{"issue":"3","key":"R8","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.tmrv.2016.03.002","volume":"30","author":"Foroutan-Rad","year":"2016","journal-title":"Transfusion Medicine Reviews"},{"key":"R9","first-page":"194","volume":"2","author":"Gu","year":"1989","journal-title":"Chinese Journal of Blood Transfusion"},{"issue":"9","key":"R10","first-page":"3","volume":"17","author":"Gu","year":"2010","journal-title":"Practical Preventive Medicine"},{"issue":"5","key":"R11","first-page":"38","volume":"7","author":"Hu","year":"1991","journal-title":"Chinese Journal of Zoonoses"},{"key":"R12","first-page":"245","volume":"10","author":"Huang","year":"2013","journal-title":"Henan Traditional Chinese Medicine"},{"key":"R13","first-page":"859","volume":"16","author":"Jiang","year":"2006","journal-title":"Chinese Journal of Health Laboratory Technology"},{"key":"R14","first-page":"37","volume":"7","author":"Jiang","year":"1991","journal-title":"Chinese Journal of Zoonoses"},{"issue":"1","key":"R15","first-page":"56","volume":"17","author":"Kuang","year":"2002","journal-title":"Virologica Sinica"},{"key":"R16","first-page":"278","volume":"16","author":"Li","year":"2003","journal-title":"Chinese Journal of Blood Transfusion"},{"key":"R17","first-page":"45","volume":"21","author":"Liu","year":"2001","journal-title":"Acta Academiae Medicine Xuzhou"},{"key":"R18","first-page":"71","volume":"24","author":"Luo","year":"2003","journal-title":"Chinese Journal of Epidemiology"},{"issue":"3","key":"R19","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.transci.2017.03.011","volume":"56","author":"Mansouri","year":"2017","journal-title":"Transfusion and Apheresis Science"},{"key":"R20","unstructured":"Martin P, Bouza P. 2004. Blood and tissue protozoa, in Infectious diseases, 2nd edn. Cohen J, Powderly WG, Editors. Mosby: Philadelphia, PA."},{"key":"R21","first-page":"43","volume":"9","author":"Meng","year":"1996","journal-title":"Chinese Journal of Blood Transfusion"},{"key":"R22","unstructured":"Ministry ohotPsRoC. Blood Donor Physical Examination Requirements (GB18467-2001)."},{"issue":"7","key":"R23","doi-asserted-by":"crossref","first-page":"e1000097","DOI":"10.1371\/journal.pmed.1000097","volume":"6","author":"Moher","year":"2009","journal-title":"PLOS Medicine"},{"key":"R24","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.3389\/fmicb.2017.01825","volume":"8","author":"Pan","year":"2017","journal-title":"Frontiers in Microbiology"},{"issue":"2","key":"R25","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1128\/CMR.05013-11","volume":"25","author":"Robert-Gangneux","year":"2012","journal-title":"Clinical Microbiology Reviews"},{"issue":"3","key":"R26","first-page":"40","volume":"7","author":"Schwarzer","year":"2007","journal-title":"R News"},{"key":"R27","first-page":"179","volume":"3","author":"Shen","year":"2000","journal-title":"Labeled Immunoassays and Clinical Medicine"},{"issue":"10","key":"R28","first-page":"2","volume":"33","author":"Shen","year":"2017","journal-title":"Journal of Medical Pest Control"},{"issue":"4","key":"R29","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1182\/blood.V37.4.388.388","volume":"37","author":"Siegel","year":"1971","journal-title":"Blood"},{"key":"R30","first-page":"835","volume":"22","author":"Song","year":"2009","journal-title":"Chinese Journal of Blood Transfusion"},{"issue":"3","key":"R31","first-page":"371","volume":"24","author":"Song","year":"2012","journal-title":"Chinese Journal of Schistosomiasis Control"},{"issue":"1661","key":"R32","first-page":"20140033","volume":"370","author":"Sun","year":"2015","journal-title":"Chinese Journal of Blood Transfusion"},{"key":"R33","first-page":"129","volume":"6","author":"Sun","year":"1991","journal-title":"Xiangjiang Laboratory Medicine"},{"issue":"12\u201313","key":"R34","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/S0020-7519(00)00124-7","volume":"30","author":"Tenter","year":"2000","journal-title":"International Journal of Parasitology"},{"key":"R35","first-page":"40","volume":"7","author":"Tong","year":"1994","journal-title":"Chinese Journal of Blood Transfusion"},{"issue":"4","key":"R36","first-page":"45","volume":"10","author":"Wang","year":"1994","journal-title":"Chinese Journal of Zoonoses"},{"key":"R37","first-page":"40","volume":"1","author":"Wang","year":"1999","journal-title":"Journal of Clinical Transfusion and Laboratory Medicine"},{"key":"R38","first-page":"124","volume":"19","author":"Wang","year":"1998","journal-title":"Medical Journal of National Defending Forces in Northwest China"},{"key":"R39","first-page":"37","volume":"23","author":"Wang","year":"2002","journal-title":"Journal of Mudanjiang Medical College"},{"issue":"21","key":"R40","first-page":"3992","volume":"20","author":"Wang","year":"2014","journal-title":"Medical Recapitulate"},{"issue":"6","key":"R41","first-page":"350","volume":"6","author":"Wu","year":"1994","journal-title":"Chinese Journal of Schistosomiasis Control"},{"key":"R42","first-page":"377","volume":"29","author":"Wu","year":"2017","journal-title":"Chinese Journal of Schistosomiasis Control"},{"key":"R43","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-2334-10-4","volume":"10","author":"Xiao","year":"2010","journal-title":"BMC Infectious Diseases"},{"key":"R44","first-page":"121","volume":"4","author":"Xie","year":"1964","journal-title":"Jiangxi Medicine"},{"issue":"3","key":"R45","first-page":"254, 258","volume":"25","author":"Xin","year":"2013","journal-title":"Chinese Journal of Schistosomiasis Control"},{"issue":"3","key":"R46","first-page":"1","volume":"27","author":"Xu","year":"2000","journal-title":"Modern Preventive Medicine"},{"issue":"2","key":"R47","first-page":"3","volume":"30","author":"Xu","year":"2017","journal-title":"Chinese Journal of Blood Transfusion"},{"key":"R48","first-page":"152","volume":"8","author":"Yang","year":"1995","journal-title":"Chinese Journal of Blood Transfusion"},{"issue":"6","key":"R49","first-page":"728, 730","volume":"24","author":"Yang","year":"2012","journal-title":"Chinese Journal of Schistosomiasis Control"},{"issue":"1","key":"R50","first-page":"109","volume":"26","author":"Yang","year":"2014","journal-title":"Chinese Journal of Schistosomiasis Control"},{"key":"R51","first-page":"101","volume":"5","author":"Yu","year":"1957","journal-title":"China Acta Microbiologica Sinica"},{"key":"R52","first-page":"241","volume":"12","author":"Yu","year":"1994","journal-title":"Chinese Journal of Parasitology and Parasitic Diseases"},{"key":"R53","first-page":"386","volume":"11","author":"Yuan","year":"1998","journal-title":"Journal of Radioimmunology"},{"issue":"3","key":"R54","first-page":"3","volume":"5","author":"Zeng","year":"2005","journal-title":"China Tropical Medicine"},{"issue":"4","key":"R55","first-page":"4","volume":"16","author":"Zhong","year":"2010","journal-title":"International Medicine & Health Guidance News"},{"key":"R56","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.pt.2008.01.001","volume":"24","author":"Zhou","year":"2008","journal-title":"Trends in Parasitology"},{"key":"R57","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1186\/1756-3305-4-165","volume":"4","author":"Zhou","year":"2011","journal-title":"Parasites & Vectors"},{"issue":"4","key":"R58","first-page":"4","volume":"9","author":"Zhu","year":"2007","journal-title":"Journal of Clinical Transfusion & Laboratory Medicine"},{"key":"R59","first-page":"81","volume":"3","author":"Zhu","year":"1987","journal-title":"Chinese Journal of Public Health"},{"key":"R60","first-page":"192","volume":"2","author":"Zhu","year":"1989","journal-title":"Chinese Journal of Transfusion"},{"key":"R61","first-page":"108","volume":"6","author":"Zhu","year":"1994","journal-title":"Chinese Journal of Schistosomiasis Control"},{"key":"R62","first-page":"1003","volume":"9","author":"Zhu","year":"1997","journal-title":"Journal of Radioimmunology"}],"container-title":["Parasite"],"original-title":[],"link":[{"URL":"https:\/\/www.parasite-journal.org\/10.1051\/parasite\/2018037\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T08:19:48Z","timestamp":1584692388000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.parasite-journal.org\/10.1051\/parasite\/2018037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":62,"alternative-id":["parasite180051"],"URL":"https:\/\/doi.org\/10.1051\/parasite\/2018037","relation":{},"ISSN":["1776-1042"],"issn-type":[{"value":"1776-1042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}