{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T21:58:45Z","timestamp":1789855125366,"version":"4.0.1"},"reference-count":12,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2018,7,16]],"date-time":"2018-07-16T00:00:00Z","timestamp":1531699200000},"content-version":"vor","delay-in-days":196,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite"],"accepted":{"date-parts":[[2018,6,25]]},"published-print":{"date-parts":[[2018]]},"abstract":"<jats:p>We highlight the absence of high-level evidence from dose-ranging studies regarding the use of oral ivermectin in susceptible parasitic diseases. We provide published data supporting the use of a higher dosage regimen of ivermectin in malaria and difficult-to-treat head lice, and announce an ongoing randomized clinical trial in severe scabies.<\/jats:p>","DOI":"10.1051\/parasite\/2018039","type":"journal-article","created":{"date-parts":[[2018,7,17]],"date-time":"2018-07-17T08:15:21Z","timestamp":1531815321000},"page":"33","source":"Crossref","is-referenced-by-count":5,"title":["High-dose ivermectin in malaria and other parasitic diseases: a new step in the development of a neglected drug"],"prefix":"10.1051","volume":"25","author":[{"given":"Olivier","family":"Chosidow","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Bernigaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giao","family":"Do-Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2018,7,16]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1056\/NEJMcp052784","volume":"354","author":"Chosidow","year":"2006","journal-title":"New England Journal of Medicine"},{"issue":"8939\u2013890","key":"R2","doi-asserted-by":"crossref","first-page":"1724","DOI":"10.1016\/S0140-6736(94)92884-3","volume":"344","author":"Chosidow","year":"1994","journal-title":"Lancet"},{"key":"R3","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/S1473-3099(17)30469-3","volume":"17","author":"Chosidow","year":"2017","journal-title":"Lancet Infectious Diseases"},{"issue":"10","key":"R4","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1056\/NEJMoa0905471","volume":"362","author":"Chosidow","year":"2010","journal-title":"New England Journal of Medicine"},{"key":"R5","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1056\/NEJMct0910329","volume":"362","author":"Currie","year":"2010","journal-title":"New England Journal of Medicine"},{"issue":"3","key":"R6","first-page":"253","volume":"45","author":"Glaziou","year":"1994","journal-title":"Tropical Medicine and Parasitology"},{"issue":"12","key":"R7","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1016\/S1473-3099(17)30483-8","volume":"17","author":"Karimkhani","year":"2017","journal-title":"Lancet Infectious Diseases"},{"issue":"2","key":"R8","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1006\/pest.1999.2460","volume":"66","author":"Lee","year":"2000","journal-title":"Pesticide Biochemistry and Physiology"},{"issue":"1","key":"R9","doi-asserted-by":"crossref","first-page":"e0006020","DOI":"10.1371\/journal.pntd.0006020","volume":"12","author":"Mu\u00f1oz","year":"2018","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"24","key":"R10","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1056\/NEJMoa1500987","volume":"373","author":"Romani","year":"2015","journal-title":"New England Journal of Medicine"},{"key":"R11","first-page":"CD012994","volume":"4","author":"Rosumeck","year":"2018","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"6","key":"R12","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/S1473-3099(18)30163-4","volume":"18","author":"Smit","year":"2018","journal-title":"Lancet Infectious Diseases"}],"container-title":["Parasite"],"original-title":[],"link":[{"URL":"https:\/\/www.parasite-journal.org\/10.1051\/parasite\/2018039\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,15]],"date-time":"2020-10-15T19:12:16Z","timestamp":1602789136000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.parasite-journal.org\/10.1051\/parasite\/2018039"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":12,"alternative-id":["parasite180083"],"URL":"https:\/\/doi.org\/10.1051\/parasite\/2018039","relation":{},"ISSN":["1776-1042"],"issn-type":[{"value":"1776-1042","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018]]}}}