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The present study evaluates the performance of TL during experimental <jats:italic>T. b. brucei<\/jats:italic> infection in pigs. Eight infected pigs and four uninfected pigs were followed up with blood and plasma collection. Blood was used for parasitological investigation. TL was performed on the plasma with the LiTat 1.3, LiTat 1.5 and LiTat 1.6 VATs. All control pigs remained negative to parasitological investigation and TL. Trypanosomes were detected in all the infected pigs and the first detection was between 10 and 14 days post infection (dpi). TL results showed that infected pigs developed antibodies against the three VATs. The first antibody detections by TL occurred between 14 and 21 dpi for antibodies directed against LiTat 1.6, 21 and 168 dpi for antibodies directed against LiTat 1.5 and 70, and 182 dpi for antibodies directed against LiTat 1.3. This study highlights for the first time that TL using LiTat 1.3 and LiTat 1.5 VATs is not specific to <jats:italic>T. b. gambiense<\/jats:italic>. Development of specific diagnostic tools for the detection of <jats:italic>T. b. gambiense<\/jats:italic> infections in animals, especially in pigs, is still needed.<\/jats:p>","DOI":"10.1051\/parasite\/2022063","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T09:12:47Z","timestamp":1671613967000},"page":"61","source":"Crossref","is-referenced-by-count":8,"title":["Experimental evidence that immune trypanolysis using the LiTat 1.3 and LiTat 1.5 variant antigen types is not specific to <i>Trypanosoma brucei gambiense<\/i> in pigs"],"prefix":"10.1051","volume":"29","author":[{"given":"Kadidiata","family":"Ilboudo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert 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