{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:07:56Z","timestamp":1788210476484,"version":"build-2803163510"},"reference-count":25,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"vor","delay-in-days":161,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"The open competition program of top ten critical priorities of Agricultural Science and Technology Innovation for the 14th Five-Year Plan of Guangdong Province","award":["2023SDZG02"],"award-info":[{"award-number":["2023SDZG02"]}]},{"name":"Key Realm R&D Program of Guangdong Province","award":["2023B0202150001"],"award-info":[{"award-number":["2023B0202150001"]}]},{"name":"Science and Technology Plan Projects of  Guangdong Province","award":["2021B1212050021"],"award-info":[{"award-number":["2021B1212050021"]}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"crossref","award":["2021B1515120006"],"award-info":[{"award-number":["2021B1515120006"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Opening Project of State Key Laboratory of Swine and Poultry Breeding Industry","award":["2023QZ-NK05, 2022GZ07"],"award-info":[{"award-number":["2023QZ-NK05, 2022GZ07"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite"],"accepted":{"date-parts":[[2025,5,16]]},"published-print":{"date-parts":[[2025]]},"abstract":"<jats:p><jats:italic>Pentatrichomonas hominis<\/jats:italic> is a protozoan parasite that infects the gastrointestinal tract of humans and mammals, causing abdominal pain and diarrhea. However, its presence in pigs and its potential as a pathogen causing diarrhea in piglets have not been well studied. This study aimed to investigate the prevalence of <jats:italic>P. hominis<\/jats:italic> in pigs and its potential for zoonotic transmission. A total of 406 pig fecal samples were collected from four pig farms located in Guangdong and Anhui Provinces. Fecal DNA extraction was carried out using a commercially available kit. A nested PCR methodology was employed to detect the presence of <jats:italic>P. hominis<\/jats:italic> infection. Samples that tested positive were subsequently subjected to sequencing, and the genetic characteristics of the 18S ribosomal RNA (rRNA) gene were analyzed. The overall infection rate of <jats:italic>P. hominis<\/jats:italic> was 34.98% (142\/406), in Guangdong Province 28.47% (80\/281), and in Anhui Province 49.60% (62\/125). Among different age groups, suckling piglets had the highest infection rate at 40.24% (68\/169). Genetic analysis of the <jats:italic>P. hominis<\/jats:italic> isolates showed that the PH-1 genotype was predominant and had a high degree of similarity to <jats:italic>P. hominis<\/jats:italic> sequences obtained from humans, cats, and pigs, indicating the potential for zoonotic transmission. The high infection rate and genetic diversity highlight the need for effective control measures in pig farming to reduce parasite transmission and zoonotic risk.<\/jats:p>","DOI":"10.1051\/parasite\/2025027","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T07:44:37Z","timestamp":1749627877000},"page":"33","source":"Crossref","is-referenced-by-count":3,"title":["Prevalence and genetic diversity of <i>Pentatrichomonas hominis<\/i> in pig populations in Guangdong and Anhui Provinces, China"],"prefix":"10.1051","volume":"32","author":[{"given":"Pengyun","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiming","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanqin","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuanqiang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenquan","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanshan","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minna","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuhui","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongle","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangjie","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingfei","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2025,6,11]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1007\/s12639-022-01506-1","volume":"46","author":"Abdo","year":"2022","journal-title":"Journal 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Prevalence of Pentatrichomonas hominis infections in six farmed wildlife species in Jilin, China. 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