{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T18:51:19Z","timestamp":1775674279528,"version":"3.50.1"},"reference-count":35,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Research Program on Emerging and Re-Emerging Infectious Diseases from the Japan Agency for Medical Research and Development","award":["Kansensho Jitsuyoka-Ippan, grant no. 23fk0108681h0901"],"award-info":[{"award-number":["Kansensho Jitsuyoka-Ippan, grant no. 23fk0108681h0901"]}]},{"name":"JSPS KAKENHI","award":["JP20K08816"],"award-info":[{"award-number":["JP20K08816"]}]},{"name":"National Research Council of Thailand (NRCT): High-Potential Research Team Grant Program","award":["N42A670561"],"award-info":[{"award-number":["N42A670561"]}]},{"name":"Research Program from Research and Graduate studies, Khon Kaen University","award":["RP66-7-001"],"award-info":[{"award-number":["RP66-7-001"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasite"],"accepted":{"date-parts":[[2026,1,8]]},"published-print":{"date-parts":[[2026]]},"abstract":"<jats:p>\n                    Human cysticercosis is a serious zoonosis caused by infection with larvae (cysticerci) of the pork tapeworm,\n                    <jats:italic>Taenia solium<\/jats:italic>\n                    . Infection can involve the nervous system, causing chronic headache and intracranial hypertension, focal neurological deficits, epileptic seizures, and paralysis. The disease is found in developing countries, where porcine cysticercosis is prevalent and undercooked pork is habitually consumed. This study aimed to develop immunochromatography-based test (ICT) kits, using low-molecular-weight antigens purified from cyst fluids of Latin American and Asian genotypes of\n                    <jats:italic>T. solium<\/jats:italic>\n                    . To evaluate the kits, we used 164 serum samples, including 24 from proven\/confirmed cysticercosis cases, 110 from cases with other parasitoses, and 30 from healthy individuals. Diagnostic performances were calculated. The sensitivity, specificity, and accuracy were 83.3% (95% CI [62.6\u201395.3]), 93.6% (95% CI [88.1\u201397.0]), and 92.1% (95% CI [86.8\u201395.7]), respectively for the American genotype-based ICT kit, while for the Asian genotype-based ICT kit, they were 87.5% (95% CI [67.6\u201397.3]), 98.6% (95% CI [94.9\u201399.8]), and 97.0% (95% CI [93.0\u201399.0]), respectively. The sensitivity and specificity did not significantly differ between the two ICT kits (exact McNemar\u2019s test;\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&gt;\u00a00.05), with a concordance of 93.9%, represented by a Cohen\u2019s kappa of 0.77 (\n                    <jats:italic>p<\/jats:italic>\n                    \u00a0&lt;\u00a00.001), indicating substantial agreement. These results indicate that affinity-purified antigens from different geographical isolates can be used for the diagnosis of human cysticercosis. The diagnostic specificities were better than for a previously reported ICT kit that used crude antigen.\n                  <\/jats:p>","DOI":"10.1051\/parasite\/2026003","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T08:54:24Z","timestamp":1769158464000},"page":"3","source":"Crossref","is-referenced-by-count":1,"title":["Comparative assessment of immunochromatographic test kits using low-molecular-weight antigens from cyst fluids of two different genotypes of\n                    <i>Taenia solium<\/i>\n                    for serodiagnosis of human cysticercosis"],"prefix":"10.1051","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0462-6209","authenticated-orcid":false,"given":"Lakkhana","family":"Sadaow","sequence":"first","affiliation":[{"name":"Mekong Health Science Research Institute, Khon Kaen University","place":["Thailand"]},{"name":"Department of Parasitology, Faculty of Medicine, Khon Kaen 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University","place":["Thailand"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2604-0281","authenticated-orcid":false,"given":"Tongjit","family":"Thanchomnang","sequence":"additional","affiliation":[{"name":"Mekong Health Science Research Institute, Khon Kaen University","place":["Thailand"]},{"name":"Department of Parasitology, Faculty of Medicine, Mahasarakham University","place":["Thailand"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcello Otake","family":"Sato","sequence":"additional","affiliation":[{"name":"Division of Global Environment Parasitology, Faculty of Medical Technology, Niigata University of Pharmacy and Medical and Life Sciences","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2138-8783","authenticated-orcid":false,"given":"Pewpan M.","family":"Intapan","sequence":"additional","affiliation":[{"name":"Mekong Health Science Research 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