{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:29:53Z","timestamp":1793194193684,"version":"4.5.0"},"reference-count":27,"publisher":"EDP Sciences","license":[{"start":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T00:00:00Z","timestamp":1614902400000},"content-version":"vor","delay-in-days":63,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SICOT-J"],"accepted":{"date-parts":[[2021,1,26]]},"published-print":{"date-parts":[[2021]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>: Identifying the risk factors for the neurological deficit in spine tuberculosis would help surgeons in deciding on early surgery, thus reducing the morbidity related to neurological deficit. The main objective of our study was to predict the risk of neurological deficit in patients with spinal tuberculosis (TB). <jats:italic>Methods<\/jats:italic>: The demographic, clinical, radiological (X-ray and MRI) data of 105 patients with active spine TB were retrospectively analyzed. Patients were divided into two groups \u2013 with a neurological deficit (<jats:italic>n<\/jats:italic> = 52) as Group A and those without deficit (<jats:italic>n<\/jats:italic> = 53) as Group B. Univariate and multivariate logistic regression analysis was used to predict the risk factors for the neurological deficit. <jats:italic>Results<\/jats:italic>: The mean age of the patients was 38.1 years. The most common location of disease was dorsal region (35.2%). Paradiscal (77%) was the most common type of involvement. A statistically significant difference (<jats:italic>p<\/jats:italic> &lt; 0.05) was noted in the location of disease, presence of cord compression, kyphosis, cord oedema, loss of CSF anterior to the cord, and degree of canal compromise or canal encroachment between two groups. Multivariate analysis revealed kyphosis &gt; 30\u00b0 (OR \u2013 3.92, CI \u2013 1.21\u201312.7, <jats:italic>p<\/jats:italic> \u2013 0.023), canal encroachment &gt; 50% (OR \u2013 7.34, CI \u2013 2.32\u201323.17, <jats:italic>p<\/jats:italic> \u2013 0.001), and cord oedema (OR \u2013 11.93, CI \u2013 1.24\u2013114.05, <jats:italic>p<\/jats:italic> \u2013 0.03) as independent risk factors for predicting the risk of neurological deficit. <jats:italic>Conclusion<\/jats:italic>: Kyphosis &gt; 30\u00b0, cord oedema, and canal encroachment (&gt;50%) significantly predicted neurological deficit in patients with spine TB. Early surgery should be considered with all these risk factors to prevent a neurological deficit.<\/jats:p>","DOI":"10.1051\/sicotj\/2021002","type":"journal-article","created":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T09:30:50Z","timestamp":1614936650000},"page":"7","source":"Crossref","is-referenced-by-count":17,"title":["Predicting neurological deficit in patients with spinal tuberculosis \u2013 A single-center retrospective case-control study"],"prefix":"10.1051","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3528-0949","authenticated-orcid":false,"given":"Samarth","family":"Mittal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gagandeep","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaustubh","family":"Ahuja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3546-5962","authenticated-orcid":false,"given":"Syed","family":"Ifthekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1317-534X","authenticated-orcid":false,"given":"Bhaskar","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Kandwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"250","published-online":{"date-parts":[[2021,3,5]]},"reference":[{"key":"R1","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1302\/0301-620X.92B7.24668","volume":"92-B","author":"Jain","year":"2010","journal-title":"J Bone Jt Surg Br"},{"key":"R2","unstructured":"World Health Organization (2019) Global tuberculosis report 2019. Retrieved from https:\/\/www.who.int\/tb\/publications\/global_report."},{"key":"R3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1051\/sicotj\/2020002","volume":"6","author":"Kamal","year":"2020","journal-title":"SICOT-J"},{"key":"R4","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1007\/s00586-012-2335-7","volume":"22","author":"Jain","year":"2013","journal-title":"Eur Spine J"},{"key":"R5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1097\/00003086-200205000-00011","volume":"398","author":"Jain","year":"2002","journal-title":"Clin Orthop Relat Res\u00ae"},{"key":"R6","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1002\/bjs.1800228813","volume":"22","author":"Seddon","year":"1935","journal-title":"Br J Surg"},{"key":"R7","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.2106\/00004623-196749060-00012","volume":"49","author":"Hodgson","year":"1967","journal-title":"JBJS"},{"key":"R8","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/s002640050313","volume":"23","author":"Jain","year":"1999","journal-title":"Int Orthop"},{"key":"R9","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1097\/BRS.0b013e3181d265c0","volume":"36","author":"Dunn","year":"2011","journal-title":"Spine"},{"key":"R10","first-page":"132","volume":"48","author":"Jain","year":"2000","journal-title":"Neurol India"},{"key":"R11","doi-asserted-by":"crossref","first-page":"366","DOI":"10.4103\/0019-5413.136228","volume":"48","author":"Gupta","year":"2014","journal-title":"Indian J Orthop"},{"key":"R12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1051\/sicotj\/2016014","volume":"2","author":"Jain","year":"2016","journal-title":"SICOT-J"},{"key":"R13","doi-asserted-by":"crossref","first-page":"e4523","DOI":"10.1097\/MD.0000000000004523","volume":"95","author":"Wang","year":"2016","journal-title":"Medicine"},{"key":"R14","first-page":"36561","volume":"10","author":"Singh","year":"2020","journal-title":"Int J Recent Sci Res"},{"key":"R15","doi-asserted-by":"crossref","first-page":"2309499019868813","DOI":"10.1177\/2309499019868813","volume":"27","author":"Sae-Jung","year":"2019","journal-title":"J Orthop Surg"},{"key":"R16","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1179\/204577211X13207446293695","volume":"34","author":"Kirshblum","year":"2011","journal-title":"J Spinal Cord Med"},{"key":"R17","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/s00264-003-0516-z","volume":"28","author":"Jain","year":"2004","journal-title":"Int Orthop"},{"key":"R18","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.jbmt.2017.01.008","volume":"21","author":"Porto","year":"2017","journal-title":"J Bodywork Movement Ther"},{"key":"R19","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00264-011-1469-2","volume":"36","author":"Rajasekaran","year":"2012","journal-title":"Int Orthop"},{"key":"R20","doi-asserted-by":"crossref","first-page":"201","DOI":"10.7326\/0003-4819-118-3-199302010-00009","volume":"118","author":"Concato","year":"1993","journal-title":"Ann Intern Med"},{"key":"R21","doi-asserted-by":"crossref","first-page":"96S","DOI":"10.1177\/2192568218769053","volume":"8","author":"Rajasekaran","year":"2018","journal-title":"Glob Spine J"},{"key":"R22","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1302\/0301-620X.33B4.517","volume":"33","author":"Dobson","year":"1951","journal-title":"J Bone Jt Surg Br"},{"key":"R23","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s00264-011-1380-x","volume":"36","author":"Jain","year":"2012","journal-title":"Int Orthop"},{"key":"R24","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/00005792-199909000-00003","volume":"78","author":"Pertuiset","year":"1999","journal-title":"Medicine"},{"key":"R25","doi-asserted-by":"crossref","first-page":"294","DOI":"10.4184\/asj.2012.6.4.294","volume":"6","author":"Rasouli","year":"2012","journal-title":"Asian Spine J"},{"key":"R26","first-page":"320","volume":"6","author":"Kiran","year":"2007","journal-title":"J Neurosurg: Spine"},{"key":"R27","first-page":"453","volume":"75","author":"Subhadrabandhu","year":"1992","journal-title":"J Med Assoc Thailand = Chotmaihet Thangphaet"}],"container-title":["SICOT-J"],"original-title":[],"link":[{"URL":"https:\/\/www.sicot-j.org\/10.1051\/sicotj\/2021002\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,5]],"date-time":"2021-03-05T09:31:12Z","timestamp":1614936672000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.sicot-j.org\/10.1051\/sicotj\/2021002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"references-count":27,"alternative-id":["sicotj200148"],"URL":"https:\/\/doi.org\/10.1051\/sicotj\/2021002","relation":{},"ISSN":["2426-8887"],"issn-type":[{"value":"2426-8887","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021]]}}}