{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:31:44Z","timestamp":1790418704101,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1053\/ajkd.2002.32795","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T03:46:10Z","timestamp":1030247170000},"page":"1102-1112","source":"Crossref","is-referenced-by-count":57,"title":["BK virus regulatory region rearrangements in brain and cerebrospinal fluid from a leukemia patient with tubulointerstitial nephritis and meningoencephalitis"],"prefix":"10.1053","volume":"39","author":[{"given":"Gerald L.","family":"Stoner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Alappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David V.","family":"Jobes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline F.","family":"Ryschkewitsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie L.","family":"Landry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/ajkd.2002.32795_bib1","first-page":"42","article-title":"Occurrence and significance of papovaviruses BK and JC in the urine","volume":"36","author":"Arthur","year":"1989","journal-title":"Prog Med Virol"},{"key":"10.1053\/ajkd.2002.32795_bib2","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1093\/infdis\/161.6.1128","article-title":"High incidence of urinary JC virus excretion in nonimmunosuppressed older patients","volume":"161","author":"Kitamura","year":"1990","journal-title":"J Infect Dis"},{"key":"10.1053\/ajkd.2002.32795_bib3","first-page":"970","article-title":"Human polyomaviruses","author":"Hogan","year":"1991"},{"key":"10.1053\/ajkd.2002.32795_bib4","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1086\/517340","article-title":"Investigation of human urine for genomic sequences of the primate polyomaviruses simian virus 40, BK virus, and JC virus","volume":"176","author":"Shah","year":"1997","journal-title":"J Infect Dis"},{"key":"10.1053\/ajkd.2002.32795_bib5","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1016\/S0140-6736(71)91777-6","article-title":"Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy","volume":"1","author":"Padgett","year":"1971","journal-title":"Lancet"},{"key":"10.1053\/ajkd.2002.32795_bib6","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1128\/JVI.51.2.458-469.1984","article-title":"Human polyomavirus JC virus genome","volume":"51","author":"Frisque","year":"1984","journal-title":"J Virol"},{"key":"10.1053\/ajkd.2002.32795_bib7","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/13550289809113482","article-title":"Progressive multifocal leukoencephalopathy in patients with HIV infection","volume":"4","author":"Berger","year":"1998","journal-title":"J Neurovirol"},{"key":"10.1053\/ajkd.2002.32795_bib8","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1128\/CMR.5.1.49","article-title":"Pathogenesis and molecular biology of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain","volume":"5","author":"Major","year":"1992","journal-title":"Clin Microbiol Rev"},{"key":"10.1053\/ajkd.2002.32795_bib9","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1136\/jcp.31.4.338","article-title":"Human polyomavirus (BK) infection and ureteric stenosis in renal allograft recipients","volume":"31","author":"Coleman","year":"1978","journal-title":"J Clin Pathol"},{"key":"10.1053\/ajkd.2002.32795_bib10","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/S0046-8177(99)90252-6","article-title":"Human polyoma virus in renal allograft biopsies: Morphological findings and correlation with urine cytology","volume":"30","author":"Drachenberg","year":"1999","journal-title":"Hum Pathol"},{"key":"10.1053\/ajkd.2002.32795_bib11","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1681\/ASN.V1051080","article-title":"Polyomavirus infection of renal allograft recipients: From latent infection to manifest disease","volume":"10","author":"Nickeleit","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"10.1053\/ajkd.2002.32795_bib12","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/00007890-199901150-00018","article-title":"Human polyoma virus-associated interstitial nephritis in the allograft kidney","volume":"67","author":"Randhawa","year":"1999","journal-title":"Transplantation"},{"key":"10.1053\/ajkd.2002.32795_bib13","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1056\/NEJM198607243150405","article-title":"Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants","volume":"315","author":"Arthur","year":"1986","journal-title":"N Engl J Med"},{"key":"10.1053\/ajkd.2002.32795_bib14","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/infdis\/158.3.563","article-title":"BK and JC virus infections in recipients of bone marrow transplants","volume":"158","author":"Arthur","year":"1988","journal-title":"J Infect Dis"},{"key":"10.1053\/ajkd.2002.32795_bib15","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/jmv.1890450214","article-title":"Renal failure due to BK virus infection in an immunodeficient child","volume":"45","author":"De Silva","year":"1995","journal-title":"J Med Virol"},{"key":"10.1053\/ajkd.2002.32795_bib16","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1056\/NEJM198305193082004","article-title":"Tubulo-interstitial nephritis associated with polyomavirus (BK type) infection","volume":"308","author":"Rosen","year":"1983","journal-title":"N Engl J Med"},{"key":"10.1053\/ajkd.2002.32795_bib17","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1128\/JCM.36.6.1660-1665.1998","article-title":"Tubulointerstitial nephritis due to a mutant polyomavirus BK strain, BKV (Cin), causing end-stage renal disease","volume":"36","author":"Smith","year":"1998","journal-title":"J Clin Microbiol"},{"key":"10.1053\/ajkd.2002.32795_bib18","first-page":"29","article-title":"Disseminated BK type polyomavirus infection in an AIDS patient associated with central nervous system disease","volume":"143","author":"Vallbracht","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1053\/ajkd.2002.32795_bib19","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1097\/00002030-199906180-00010","article-title":"BK virus as the cause of meningoencephalitis, retinitis and nephritis in a patient with AIDS","volume":"13","author":"Bratt","year":"1999","journal-title":"AIDS"},{"key":"10.1053\/ajkd.2002.32795_bib20","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1097\/00002030-200106150-00026","article-title":"BK virus encephalitis in a patient with AIDS and lymphoma","volume":"15","author":"Lesprit","year":"2001","journal-title":"AIDS"},{"key":"10.1053\/ajkd.2002.32795_bib21","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1001\/archneur.1996.00550010121025","article-title":"BK virus encephalitis in an immunocompetent patient","volume":"53","author":"Voltz","year":"1996","journal-title":"Arch Neurol"},{"key":"10.1053\/ajkd.2002.32795_bib22","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1099\/0022-1317-74-8-1499","article-title":"Human polyomavirus JC promoter\/enhancer rearrangement patterns from progressive multifocal leukoencephalopathy brain are unique derivatives of a single archetypal structure","volume":"74","author":"Ault","year":"1993","journal-title":"J Gen Virol"},{"key":"10.1053\/ajkd.2002.32795_bib23","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1099\/0022-1317-78-3-659","article-title":"JC virus regulatory region rearrangements and genotypes in progressive multifocal leukoencephalopathy: Two independent aspects of virus variation","volume":"78","author":"Agostini","year":"1997","journal-title":"J Gen Virol"},{"key":"10.1053\/ajkd.2002.32795_bib24","doi-asserted-by":"crossref","first-page":"398","DOI":"10.3109\/13550280009018304","article-title":"Analysis of the transcriptional control region in progressive multifocal leukoencephalopathy","volume":"6","author":"Vaz","year":"2000","journal-title":"J Neurovirol"},{"key":"10.1053\/ajkd.2002.32795_bib25","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3109\/13550289909021994","article-title":"Detection and typing of JC virus in autopsy brains and extraneural organs of AIDS patients and non-immunocompromised individuals","volume":"5","author":"Caldarelli-Stefano","year":"1999","journal-title":"J Neurovirol"},{"key":"10.1053\/ajkd.2002.32795_bib26","first-page":"127","article-title":"The archetype concept and regulatory region rearrangement","author":"Yogo","year":"2001"},{"key":"10.1053\/ajkd.2002.32795_bib27","first-page":"503","article-title":"Progressive multifocal leukoencephalopathy","volume":"Vol 47","author":"Walker","year":"1985"},{"key":"10.1053\/ajkd.2002.32795_bib28","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1126\/science.228391","article-title":"BK virus DNA: Complete nucleotide sequence of a human tumor virus","volume":"206","author":"Yang","year":"1979","journal-title":"Science"},{"key":"10.1053\/ajkd.2002.32795_bib29","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/0092-8674(79)90209-5","article-title":"The genome of human papovavirus BKV","volume":"18","author":"Seif","year":"1979","journal-title":"Cell"},{"key":"10.1053\/ajkd.2002.32795_bib30","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1128\/JVI.63.2.901-911.1989","article-title":"Nucleotide sequence of the human polyomavirus AS virus, an antigenic variant of BK virus","volume":"63","author":"Tavis","year":"1989","journal-title":"J Virol"},{"key":"10.1053\/ajkd.2002.32795_bib31","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/jmv.1890410104","article-title":"Genomic typing of BK virus in clinical specimens by direct sequencing of polymerase chain reaction products","volume":"41","author":"Jin","year":"1993","journal-title":"J Med Virol"},{"key":"10.1053\/ajkd.2002.32795_bib32","first-page":"527","article-title":"The epidemiology of BK virus and the occurrence of antigenic and genomic subtypes","author":"Knowles","year":"2001"},{"key":"10.1053\/ajkd.2002.32795_bib33","first-page":"491","article-title":"Molecular evolution and epidemiology of JC virus","author":"Agostini","year":"2001"},{"key":"10.1053\/ajkd.2002.32795_bib34","doi-asserted-by":"crossref","first-page":"3388","DOI":"10.1128\/JVI.62.9.3388-3398.1988","article-title":"Binding of cellular proteins to the regulatory region of BK virus DNA","volume":"62","author":"Markowitz","year":"1988","journal-title":"J Virol"},{"key":"10.1053\/ajkd.2002.32795_bib35","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF01701816","article-title":"Noncoding control region of naturally occurring BK virus variants: Sequence comparison and functional analysis","volume":"10","author":"Moens","year":"1995","journal-title":"Virus Genes"},{"key":"10.1053\/ajkd.2002.32795_bib36","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/BF00315259","article-title":"BK virus DNA cloned directly from human urine confirms an archetypal structure for the transcriptional control region","volume":"2","author":"Rubinstein","year":"1988","journal-title":"Virus Genes"},{"key":"10.1053\/ajkd.2002.32795_bib37","first-page":"359","article-title":"Molecular biology of BK virus and clinical and basic aspects of BK virus renal infection","author":"Moens","year":"2001"},{"key":"10.1053\/ajkd.2002.32795_bib38","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1007\/BF01322682","article-title":"BK virus and a new type of JC virus excreted by HIV-1 positive patients in rural Tanzania","volume":"140","author":"Agostini","year":"1995","journal-title":"Arch Virol"},{"key":"10.1053\/ajkd.2002.32795_bib39","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1128\/JCM.34.1.159-164.1996","article-title":"Genotype profile of human polyomavirus JC excreted in urine of immunocompetent individuals","volume":"34","author":"Agostini","year":"1996","journal-title":"J Clin Microbiol"},{"key":"10.1053\/ajkd.2002.32795_bib40","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1128\/JVI.64.8.3864-3871.1990","article-title":"At least two types of control regions can be found among naturally occurring BK virus strains","volume":"64","author":"Sundsfjord","year":"1990","journal-title":"J Virol"},{"key":"10.1053\/ajkd.2002.32795_bib41","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0969-2126(96)00020-2","article-title":"The structure of simian virus 40 refined at 3.1 \u00c5 resolution","volume":"4","author":"Stehle","year":"1996","journal-title":"Structure"},{"key":"10.1053\/ajkd.2002.32795_bib42","first-page":"257","article-title":"The neuropathology and pathogenesis of progressive multifocal leukoencephalopathy","author":"M\u00e1zl\u00f3","year":"2001"},{"key":"10.1053\/ajkd.2002.32795_bib43","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/(SICI)1096-9071(200003)60:3<353::AID-JMV16>3.0.CO;2-R","article-title":"Identification of archetype and rearranged forms of BK virus in leukocytes from healthy individuals","volume":"60","author":"Chatterjee","year":"2000","journal-title":"J Med Virol"},{"key":"10.1053\/ajkd.2002.32795_bib44","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1002\/jlb.65.4.428","article-title":"Viral variant nucleotide sequences help expose leukocytic positioning in the JC virus pathway to the CNS","volume":"65","author":"Jensen","year":"1999","journal-title":"J Leukoc Biol"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638602755509?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638602755509?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T06:25:09Z","timestamp":1621146309000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638602755509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S0272638602755509"],"URL":"https:\/\/doi.org\/10.1053\/ajkd.2002.32795","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}