{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T22:17:19Z","timestamp":1767824239372,"version":"3.49.0"},"reference-count":80,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2000,8,1]],"date-time":"2000-08-01T00:00:00Z","timestamp":965088000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice & Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2000,8]]},"DOI":"10.1053\/bega.2000.0105","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T13:54:50Z","timestamp":1032443690000},"page":"585-599","source":"Crossref","is-referenced-by-count":24,"title":["Autoimmune tests in primary biliary cirrhosis"],"prefix":"10.1053","volume":"14","author":[{"given":"Christian P.","family":"Strassburg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael P.","family":"Manns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/bega.2000.0105_RF1","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0950-3528(96)90056-1","article-title":"Immunogenetics in liver disease","volume":"10","author":"Donaldson","year":"1996","journal-title":"Bailli\u00e8res Clinical Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1055\/s-2007-1007178","article-title":"The nature of autoimmune disease","volume":"17","author":"Mackay","year":"1997","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2000.0105_RF3","first-page":"3048","article-title":"The epidemiology of primary biliary cirrhosis: immunological problems","volume":"46","author":"Uibo","year":"1999","journal-title":"Hepatogastroenterology"},{"key":"10.1053\/bega.2000.0105_RF4","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/S0168-8278(05)80137-0","article-title":"Familial primary biliary cirrhosis","volume":"20","author":"Bach","year":"1994","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF5","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0168-8278(99)80097-X","article-title":"Familial primary biliary cirrhosis reassessed: a geographically-based population study","volume":"30","author":"Jones","year":"1999","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF6","first-page":"188","article-title":"Familial primary biliary cirrhosis. Immunological and genetic study","volume":"75","author":"Kato","year":"1981","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/jaut.1999.0299","article-title":"Familial primary biliary cirrhosis in Hiroshima","volume":"13","author":"Tsuji","year":"1999","journal-title":"Journal of Autoimmunity"},{"key":"10.1053\/bega.2000.0105_RF8","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1007\/BF00194235","article-title":"Chromosomal aberrations in patients with primary biliary cirrhosis","volume":"85","author":"Notghi","year":"1990","journal-title":"Human Genetics"},{"key":"10.1053\/bega.2000.0105_RF9","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1016\/0016-5085(94)90427-8","article-title":"Immunogenetics of chronic liver diseases","volume":"106","author":"Manns","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF10","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1016\/0016-5085(91)90090-8","article-title":"HLA DRw8 and complement C4 deficiency as risk factors in primary biliary cirrhosis","volume":"101","author":"Manns","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF11","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1002\/hep.1840200517","article-title":"Defining the immunogenetic susceptibility to primary biliary cirrhosis","volume":"20","author":"Mehal","year":"1994","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF12","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0168-8278(05)80617-8","article-title":"DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis","volume":"21","author":"Onishi","year":"1994","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF13","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0168-8278(99)80238-4","article-title":"TNF gene polymorphisms in primary biliary cirrhosis: a critical appraisal","volume":"31","author":"Donaldson","year":"1999","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF14","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/S0168-8278(99)80220-7","article-title":"Primary biliary cirrhosis shows association with genetic polymorphism of tumour necrosis factor alpha promoter region","volume":"31","author":"Gordon","year":"1999","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF15","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1111\/j.1600-0676.1995.tb00687.x","article-title":"Mitochondrial antigen\/antibody systems in primary biliary cirrhosis: revisited","volume":"15","author":"Berg","year":"1995","journal-title":"Liver"},{"key":"10.1053\/bega.2000.0105_RF16","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1056\/NEJM195801232580407","article-title":"Primary biliary cirrhosis showing a high titer of autoantibody","volume":"258","author":"Mackay","year":"1958","journal-title":"New England Journal of Medicine"},{"key":"10.1053\/bega.2000.0105_RF17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/hep.1840020102","article-title":"A mitochondrial antigen-antibody system in cholestatic liver disease detected by radioimmunoassay","volume":"2","author":"Manns","year":"1982","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF18","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/00042737-199906000-00003","article-title":"Anti-mitochondrial antibodies and other immunological tests in primary biliary cirrhosis","volume":"11","author":"Strassburg","year":"1999","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2000.0105_RF19","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/hep.1840080128","article-title":"Primary biliary cirrhosis and mitochondrial autoantigens\u2014insights from molecular biology","volume":"8","author":"Gershwin","year":"1988","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF20","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/0016-5085(91)80033-6","article-title":"Primary biliary cirrhosis: paradigm or paradox for autoimmunity","volume":"100","author":"Gershwin","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF21","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1600-0676.1984.tb00918.x","article-title":"Profiles of antinuclear antibodies in chronic active hepatitis, primary biliary cirrhosis and alcoholic liver disease","volume":"4","author":"Kurki","year":"1984","journal-title":"Liver"},{"key":"10.1053\/bega.2000.0105_RF22","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0016-5085(90)91246-3","article-title":"Antinuclear antibodies directed to a 200-kilodalton polypeptide of the nuclear envelope in primary biliary cirrhosis. A clinical and immunological study of a series of 150 patients with primary biliary cirrhosis","volume":"99","author":"Lassoued","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF23","first-page":"1123","article-title":"Prevalence, kinetics, and therapeutic modulation of autoantibodies against Sp100 and promyelocytic leukemia protein in a large cohort of patients with primary biliary cirrhosis","volume":"26","author":"Zuchner","year":"1997","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF24","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1055\/s-2008-1040504","article-title":"Molecular definitions, autoepitopes, and enzymatic activities of the mitochondrial autoantigens of primary biliary cirrhosis","volume":"9","author":"van de Water","year":"1989","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2000.0105_RF25","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0168-8278(05)80139-4","article-title":"Primary biliary cirrhosis: survival of a large cohort of symptomatic and asymptomatic patients followed for 24 years","volume":"20","author":"Mahl","year":"1994","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF26","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1097\/00042737-199906000-00002","article-title":"Immunopathology of primary biliary cirrhosis","volume":"11","author":"Joplin","year":"1999","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2000.0105_RF27","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S0168-8278(05)80276-4","article-title":"Autoreactive liver-infiltrating T cells in primary biliary cirrhosis recognize inner mitochondrial epitopes and the pyruvate dehydrogenase complex","volume":"18","author":"Lohr","year":"1993","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF28","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1055\/s-2007-1007188","article-title":"The role of T cells in primary biliary cirrhosis","volume":"17","author":"van de Water","year":"1997","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2000.0105_RF29","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1084\/jem.126.2.277","article-title":"Mitochondrial antibodies in primary biliary cirrhosis. I. Localization of the antigen to mitochondrial membranes","volume":"126","author":"Berg","year":"1967","journal-title":"Journal of Experimental Medicine"},{"key":"10.1053\/bega.2000.0105_RF30","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/BF01728613","article-title":"Mitochondrial antigens and autoantibodies: from anti-M1 to anti-M9","volume":"64","author":"Berg","year":"1986","journal-title":"Klinische Wochenschrift"},{"key":"10.1053\/bega.2000.0105_RF31","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.4049\/jimmunol.135.3.1739","article-title":"Reactivity of anti-mitochondrial autoantibodies in primary biliary cirrhosis: definition of two novel mitochondrial polypeptide autoantigens","volume":"135","author":"Frazer","year":"1985","journal-title":"Journal of Immunology"},{"key":"10.1053\/bega.2000.0105_RF32","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0165-2478(85)90057-4","article-title":"Multiplicity of mitochondrial inner membrane antigens from beef heart reacting with antimitochondrial antibodies in sera of patients with primary biliary cirrhosis","volume":"9","author":"Ishii","year":"1985","journal-title":"Immunology Letters"},{"key":"10.1053\/bega.2000.0105_RF33","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1002\/hep.1840050510","article-title":"Mitochondrial antibodies in primary biliary cirrhosis: species and nonspecies specific determinants of M2 antigen","volume":"5","author":"Lindenborn-Fotinos","year":"1985","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF34","first-page":"59","article-title":"Characterization of primary biliary cirrhosis (PBC) specific mitochondrial determinants by immunoblotting","volume":"47","author":"Manns","year":"1987","journal-title":"Deutsche Zeitschrift f\u00fcr Verdauungs- und Stoffwechselkrankheiten"},{"key":"10.1053\/bega.2000.0105_RF35","doi-asserted-by":"crossref","first-page":"A85","DOI":"10.1016\/S0168-8278(85)80243-9","article-title":"Characterization of primary biliary cirrhosis (PBC) specific mitochondrial determinants by immunoblotting","volume":"1","author":"Manns","year":"1985","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF36","doi-asserted-by":"crossref","first-page":"3525","DOI":"10.4049\/jimmunol.138.10.3525","article-title":"Identification and specificity of a cDNA encoding the 70kd mitochondrial antigen recognized in primary biliary cirrhosis","volume":"138","author":"Gershwin","year":"1987","journal-title":"Journal of Immunology"},{"key":"10.1053\/bega.2000.0105_RF37","first-page":"47","article-title":"Molecular biology of the 2-oxo-acid dehydrogenase complexes and anti-mitochondrial antibodies","volume":"10","author":"Gershwin","year":"1992","journal-title":"Progress in Liver Disease"},{"key":"10.1053\/bega.2000.0105_RF38","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1084\/jem.167.6.1791","article-title":"The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase","volume":"167","author":"van de Water","year":"1988","journal-title":"Journal of Experimental Medicine"},{"key":"10.1053\/bega.2000.0105_RF39","first-page":"505","article-title":"Autoantibodies to BCOADC-E2 in patients with primary biliary cirrhosis recognize a conformational epitope","volume":"22","author":"Leung","year":"1995","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF40","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/hep.510230307","article-title":"Epitope mapping and reactivity of autoantibodies to the E2 component of 2-oxoglutarate dehydrogenase complex in primary biliary cirrhosis using recombinant 2-oxoglutarate dehydrogenase complex","volume":"23","author":"Moteki","year":"1996","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF41","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1002\/art.1780380715","article-title":"Autoantibodies to pyruvate dehydrogenase complex in patients with systemic sclerosis. Possible role of anti-E1 alpha antibody as a serologic indicator for development of primary biliary cirrhosis","volume":"38","author":"Fujimoto","year":"1995","journal-title":"Arthritis and Rheumatism"},{"key":"10.1053\/bega.2000.0105_RF42","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1006\/jaut.1996.0015","article-title":"Molecular aspects and the pathological basis of primary biliary cirrhosis","volume":"9","author":"Leung","year":"1996","journal-title":"Journal of Autoimmunity"},{"key":"10.1053\/bega.2000.0105_RF43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/hep.510300106","article-title":"Characterization of the autoantibody responses to recombinant E3 binding protein (protein X) of pyruvate dehydrogenase in primary biliary cirrhosis","volume":"30","author":"Palmer","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF44","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1002\/hep.510250506","article-title":"Comparative studies of antimitochondrial autoantibodies in sera and bile in primary biliary cirrhosis","volume":"25","author":"Nishio","year":"1997","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF45","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1002\/path.1711760409","article-title":"Subcellular localization of pyruvate dehydrogenase dihydrolipoamide acetyltransferase in human intrahepatic biliary epithelial cells","volume":"176","author":"Joplin","year":"1995","journal-title":"Journal of Pathology"},{"key":"10.1053\/bega.2000.0105_RF46","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/hep.510310106","article-title":"Evidence for a locally driven mucosal response and the presence of mitochondrial antigens in saliva in primary biliary cirrhosis","volume":"31","author":"Reynoso-Paz","year":"2000","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF47","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/0168-8278(91)90903-O","article-title":"Antimitochondrial antibody profiles determined at early stages of primary biliary cirrhosis differentiate between a benign and a progressive course of the disease. A retrospective analysis of 76 patients over 6\u201318 years","volume":"12","author":"Klein","year":"1991","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF48","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1600-0676.1997.tb00793.x","article-title":"Antimitochondrial antibody profiles in primary biliary cirrhosis distinguish at early stages between a benign and a progressive course: a prospective study on 200 patients followed for 10 years","volume":"17","author":"Klein","year":"1997","journal-title":"Liver"},{"key":"10.1053\/bega.2000.0105_RF49","first-page":"445","article-title":"Anti-M4 antibodies in primary biliary cirrhosis react with sulphite oxidase, an enzyme of the mitochondrial inter-membrane space","volume":"84","author":"Klein","year":"1991","journal-title":"Clinical and Experimental Immunology"},{"key":"10.1053\/bega.2000.0105_RF50","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1002\/hep.1840160505","article-title":"M4 and M9 antibodies in the overlap syndrome of primary biliary cirrhosis and chronic active hepatitis: epitopes or epiphenomena?","volume":"16","author":"Davis","year":"1992","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF51","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0168-8278(05)80253-3","article-title":"M4 and M9 autoantigens in primary biliary cirrhosis\u2014a negative study","volume":"18","author":"Palmer","year":"1993","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF52","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1002\/hep.510250103","article-title":"Quantitative measurement of autoantibodies to recombinant mitochondrial antigens in patients with primary biliary cirrhosis: relationship of levels of autoantibodies to disease progression","volume":"25","author":"van Norstrand","year":"1997","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF53","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/hep.1840070125","article-title":"Subtypes of antimitochondrial antibodies in primary biliary cirrhosis before and after orthotopic liver transplantation","volume":"7","author":"Haagsma","year":"1987","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF54","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1006\/jaut.1997.0156","article-title":"Persistence of autoantibodies against recombinant mitochondrial and nuclear pore proteins after orthotopic liver transplantation for primary biliary cirrhosis","volume":"10","author":"Mattalia","year":"1997","journal-title":"Journal of Autoimmunity"},{"key":"10.1053\/bega.2000.0105_RF55","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0168-8278(05)80497-0","article-title":"Is there recurrence of primary biliary cirrhosis after liver transplantation? A clinicopathologic study in long-term survivors","volume":"20","author":"Gouw","year":"1994","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF56","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1097\/00042737-199906000-00009","article-title":"Clinical relevance of recurrence of primary biliary cirrhosis after liver transplantation","volume":"11","author":"Haagsma","year":"1999","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2000.0105_RF57","series-title":"Current Therapy in Allergy, Immunology and Rheumatology","first-page":"301","article-title":"Chronic hepatitis","author":"Manns","year":"1996"},{"key":"10.1053\/bega.2000.0105_RF58","series-title":"Klinik der Gegewart","first-page":"1","article-title":"Immunological, serological and molecular biological tests in liver diseases","author":"Strassburg","year":"1998"},{"key":"10.1053\/bega.2000.0105_RF59","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0090-1229(88)90066-9","article-title":"Antinuclear antibodies (ANAs): diagnostically specific immune markers and clues toward the understanding of systemic autoimmunity","volume":"47","author":"Tan","year":"1988","journal-title":"Clinical Immunology and Immunopathology"},{"key":"10.1053\/bega.2000.0105_RF60","doi-asserted-by":"crossref","first-page":"4423","DOI":"10.1128\/MCB.19.6.4423","article-title":"Structural and functional heterogeneity of nuclear bodies","volume":"19","author":"Bloch","year":"1999","journal-title":"Molecular and Cell Biology"},{"key":"10.1053\/bega.2000.0105_RF61","first-page":"461","article-title":"Primary biliary cirrhosis and the molecular cell biology of the nuclear envelope","volume":"61","author":"Worman","year":"1994","journal-title":"Mount Sinai Journal of Medicine"},{"key":"10.1053\/bega.2000.0105_RF62","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0016-5085(94)95333-3","article-title":"Autoantibodies against integral membrane proteins of the nuclear envelope in patients with primary biliary cirrhosis","volume":"106","author":"Nickowitz","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF63","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/hep.510230512","article-title":"Specificity and sensitivity of gp210 autoantibodies detected using an enzyme-linked immunosorbent assay and a synthetic polypeptide in the diagnosis of primary biliary cirrhosis","volume":"23","author":"Bandin","year":"1996","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF64","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0168-8278(98)80220-1","article-title":"Persistence of gp210 and multiple nuclear dots antibodies does not correlate with recurrence of primary biliary cirrhosis 6 years after liver transplantation","volume":"28","author":"Dubel","year":"1998","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF65","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/S0168-8278(98)80233-X","article-title":"The antinuclear autoantibodies Sp100 and gp210 persist after orthotopic liver transplantation in patients with primary biliary cirrhosis","volume":"28","author":"Luettig","year":"1998","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF66","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1084\/jem.178.6.2237","article-title":"Autoantibodies from patients with primary biliary cirrhosis recognize a restricted region within the cytoplasmic tail of nuclear pore membrane glycoprotein Gp210","volume":"178","author":"Nickowitz","year":"1993","journal-title":"Journal of Experimental Medicine"},{"key":"10.1053\/bega.2000.0105_RF67","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1053\/gast.1996.v110.pm8608894","article-title":"Autoantibodies against nucleoporin p62 constitute a novel marker of primary biliary cirrhosis","volume":"110","author":"Wesierska-Gadek","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0105_RF68","first-page":"108","article-title":"Autoimmune sera recognize a 100kD nuclear protein antigen (sp-100)","volume":"68","author":"Szostecki","year":"1987","journal-title":"Clinical and Experimental Immunology"},{"key":"10.1053\/bega.2000.0105_RF69","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1365-3083.1992.tb03224.x","article-title":"Autoantibodies to the nuclear Sp100 protein in primary biliary cirrhosis and associated diseases: epitope specificity and immunoglobulin class distribution","volume":"36","author":"Szostecki","year":"1992","journal-title":"Scandinavian Journal of Immunology"},{"key":"10.1053\/bega.2000.0105_RF70","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3109\/08916939908995970","article-title":"Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology","volume":"29","author":"Bluthner","year":"1999","journal-title":"Autoimmunity"},{"key":"10.1053\/bega.2000.0105_RF71","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/S0168-8278(96)80290-X","article-title":"Identification of cyclin A as a molecular target of antinuclear antibodies (ANA) in hepatic and non-hepatic diseases","volume":"25","author":"Strassburg","year":"1996","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF72","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/hep.510230109","article-title":"Autoantibodies from patients with primary biliary cirrhosis recognize a region within the nucleoplasmic domain of inner nuclear membrane protein LBR","volume":"23","author":"Lin","year":"1996","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF73","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1365-3083.1995.tb03652.x","article-title":"Two nuclear dot-associated proteins, PML and Sp100, are often co-autoimmunogenic in patients with primary biliary cirrhosis","volume":"42","author":"Sternsdorf","year":"1995","journal-title":"Scandinavian Journal of Immunology"},{"key":"10.1053\/bega.2000.0105_RF74","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1002\/hep.510280210","article-title":"Frequency and nature of the variant syndromes of autoimmune liver disease","volume":"28","author":"Czaja","year":"1998","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF75","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1002\/hep.1840180435","article-title":"Meeting report: International autoimmune hepatitis group","volume":"18","author":"Johnson","year":"1993","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF76","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0168-8278(99)80297-9","article-title":"International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis","volume":"31","author":"Alvarez","year":"1999","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2000.0105_RF77","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1007\/BF02065530","article-title":"Autoimmune cholangitis: a variant of primary biliary cirrhosis. Clinicopathologic and serologic correlations in 200 cases","volume":"40","author":"Goodman","year":"1995","journal-title":"Digestive Disease Science"},{"key":"10.1053\/bega.2000.0105_RF78","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/hep.1840180103","article-title":"Autoimmune cholangiopathy: part of the spectrum of autoimmune chronic active hepatitis","volume":"18","author":"Ben-Ari","year":"1993","journal-title":"Hepatology"},{"key":"10.1053\/bega.2000.0105_RF79","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1136\/gut.35.2.260","article-title":"Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis","volume":"35","author":"Michieletti","year":"1994","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0105_RF80","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1016\/0016-5085(94)90829-X","article-title":"Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis?","volume":"107","author":"Colombato","year":"1994","journal-title":"Gastroenterology"}],"container-title":["Best Practice & Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691800901057?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691800901057?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T04:38:20Z","timestamp":1682138300000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691800901057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,8]]},"references-count":80,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,8]]}},"alternative-id":["S1521691800901057"],"URL":"https:\/\/doi.org\/10.1053\/bega.2000.0105","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2000,8]]}}}