{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:02:47Z","timestamp":1771016567315,"version":"3.50.1"},"reference-count":67,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2000,10,1]],"date-time":"2000-10-01T00:00:00Z","timestamp":970358400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice &amp; Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2000,10]]},"DOI":"10.1053\/bega.2000.0122","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T09:54:50Z","timestamp":1032429290000},"page":"743-757","source":"Crossref","is-referenced-by-count":49,"title":["Epidemiology and natural history of reflux disease"],"prefix":"10.1053","volume":"14","author":[{"given":"Sanjay","family":"Nandurkar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas J.","family":"Talley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/bega.2000.0122_RF1","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1136\/gut.32.2.128","article-title":"Symptomatic gastro-oesophageal reflux, abnormal oesophageal acid exposure, and mucosal acid sensitivity are three separate, though related, aspects of gastro-oesophageal reflux disease","volume":"32","author":"Howard","year":"1991","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF2","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1136\/gut.37.4.457","article-title":"Reflux related symptoms in patients with normal oesophageal exposure to acid","volume":"37","author":"Shi","year":"1995","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF3","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1136\/gut.40.5.587","article-title":"Double blind cross-over placebo controlled study of omeprazole in the treatment of patients with reflux symptoms and physiological levels of acid reflux the \u2018sensitive oesophagus\u2019","volume":"40","author":"Watson","year":"1997","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF4","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1111\/j.1572-0241.1999.00925.x","article-title":"Esophageal hypersensitivity may be a major cause of heartburn","volume":"94","author":"Rodriguez-Stanley","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF5","first-page":"3","article-title":"Functional esophageal diseases","volume":"8","author":"Richter","year":"1992","journal-title":"Gastroenterology International"},{"key":"10.1053\/bega.2000.0122_RF6","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0140-6736(90)90287-F","article-title":"Symptoms in gastro-oesophageal reflux disease","volume":"335","author":"Klauser","year":"1990","journal-title":"Lancet"},{"key":"10.1053\/bega.2000.0122_RF7","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1080\/003655298750026697","article-title":"The usefulness of a structured questionnaire in the assessment of symptomatic gastro-oesophageal reflux disease","volume":"33","author":"Carlsson","year":"1998","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF8","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0025-6196(12)62245-9","article-title":"A new questionnaire for gastro-oesophageal reflux disease","volume":"69","author":"Locke","year":"1994","journal-title":"Mayo Clinics Proceedings"},{"key":"10.1053\/bega.2000.0122_RF9","series-title":"Heartburn across America","year":"1988"},{"key":"10.1053\/bega.2000.0122_RF10","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1016\/S0016-5085(97)70025-8","article-title":"Prevalence and clinical spectrum of gastroesophageal reflux: a population based study in Olmsted County, Minnesota","volume":"112","author":"Locke","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF11","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1111\/j.1572-0241.1999.01427.x","article-title":"Prevalence and impact of upper gastrointestinal symptoms in the Canadian population: findings from the DIGEST Study","volume":"94","author":"Tougas","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.3109\/07853899509031939","article-title":"Prevalence of symptoms suggestive of gastro-oesophageal reflux disease in an adult population","volume":"27","author":"Isolauri","year":"1995","journal-title":"Annals of Medicine"},{"key":"10.1053\/bega.2000.0122_RF13","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1023\/A:1018846807296","article-title":"Prevalence and impact of symptoms of gastroesophageal reflux disease","volume":"44","author":"Valle","year":"1999","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2000.0122_RF14","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1136\/gut.44.2008.S1","article-title":"An evidence-based appraisal of reflux disease\u2014the Genval Workshop Report","volume":"44","author":"Dent","year":"1999","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF15","series-title":"L'oesophage. Manuel et atlas d'endoscopie","author":"Savary","year":"1997"},{"key":"10.1053\/bega.2000.0122_RF16","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1111\/j.1365-2036.1989.tb00212.x","article-title":"Acute treatment of reflux esophagitis: a multicentre trial to compare 150mg ranitidine with 300mg of ranitidine qds","volume":"3","author":"Johnson","year":"1989","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2000.0122_RF17","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/0016-5085(88)90162-X","article-title":"Healing and relapse of severe peptic esophagitis after treatment with omeprazole","volume":"95","author":"Hetzel","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF18","first-page":"113","article-title":"The incidence of reflux oesophagitis","volume":"28","author":"Loof","year":"1993","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF19","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1136\/bmj.302.6779.749","article-title":"Prevalence of endoscopic and histologic findings in subjects with and without dyspepsia","volume":"302","author":"Johnsen","year":"1991","journal-title":"British Medical Journal"},{"key":"10.1053\/bega.2000.0122_RF20","doi-asserted-by":"crossref","first-page":"965","DOI":"10.3109\/00365529709011211","article-title":"Omeprazole 10 milligrams once daily, omeprazole 20 milligrams once daily, or ranitidine 150 milligrams twice daily, evaluated as initial therapy for relief of symptoms of gastro-oesophageal reflux disease in general practice","volume":"32","author":"Venables","year":"1997","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF21","first-page":"A107","article-title":"The prevalence of endoscopic negative gastro-oesophageal reflux at a tertiary care center","volume":"116","author":"Achem","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF22","first-page":"1161","article-title":"Disease progression in gastro-oesophageal reflux disease as determined by repeat oesophageal pH monitoring and endoscopy 3 to 4\u00b75 years after diagnosis","volume":"9","author":"McDougall","year":"1997","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2000.0122_RF23","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1136\/gut.45.2008.ii37","article-title":"Function gastroduodenal disorders","volume":"45","author":"Talley","year":"1999","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF24","doi-asserted-by":"crossref","first-page":"987","DOI":"10.3109\/00365529209000176","article-title":"Prediction of major pathologic conditions in dyspeptic patients referred for endoscopy","volume":"27","author":"Bytzer","year":"1992","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF25","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1016\/0016-5085(92)90784-V","article-title":"Barrett's esophagus associated with adenocarcinoma","volume":"102","author":"Jochem","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF26","doi-asserted-by":"crossref","first-page":"52","DOI":"10.7326\/0003-4819-103-1-52","article-title":"Familial gastroesophageal reflux and development of Barrett's esophagus","volume":"103","author":"Crabb","year":"1985","journal-title":"Annals of Internal Medicine"},{"key":"10.1053\/bega.2000.0122_RF27","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1053\/gast.1997.v113.pm9352846","article-title":"Familial aggregation of gastroesophageal reflux in patients with Barrett's esophagus and esophageal adenocarcinoma","volume":"113","author":"Romero","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF28","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1111\/j.1572-0241.1999.01060.x","article-title":"Familial clustering of reflux symptoms","volume":"94","author":"Trudgill","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF29","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1111\/j.1572-0241.1999.01426.x","article-title":"Association of obesity with hiatal hernia and esophagitis","volume":"94","author":"Wilson","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF30","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1111\/j.1572-0241.1998.00526.x","article-title":"Prevalence of gastrointestinal symptoms in a multiracial Asian population, with particular reference to reflux-type symptoms","volume":"93","author":"Ho","year":"1998","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF31","first-page":"668","article-title":"The incidence of reflux esophagitis among the Chinese","volume":"92","author":"Chang","year":"1997","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF32","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1023\/A:1018835324210","article-title":"Erosive esophagitis and Barrett's esophagus in Taiwan. A higher frequency than expected","volume":"42","author":"Yeh","year":"1997","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2000.0122_RF33","series-title":"Directory of nutrition for people of the Republic of China","year":"1991"},{"key":"10.1053\/bega.2000.0122_RF34","series-title":"Handbook of statistics of Internal Affairs","year":"1993"},{"key":"10.1053\/bega.2000.0122_RF35","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1136\/gut.36.4.539","article-title":"Effect of Helicobacter pylori status on intragastric pH during treatment with omeprazole","volume":"36","author":"Verdu","year":"1995","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF36","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/gut.43.3.327","article-title":"Opposing time trends of peptic ulcer and reflux disease","volume":"43","author":"El-Serag","year":"1998","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF37","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0016-5085(99)70544-5","article-title":"Gastric Helicobacter pylori infection accelerates healing of reflux esophagitis during treatment with proton pump inhibitors","volume":"117","author":"Holtmann","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF38","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/S0016-5085(97)70024-6","article-title":"Curing Helicobacter pylori infection in patients with duodenal ulcer may provoke reflux esophagitis","volume":"112","author":"Labenz","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF39","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1001\/jama.1991.03460100089030","article-title":"Rising incidence of adenocarcinoma of the esophagus and gastric cardia","volume":"265","author":"Blot","year":"1991","journal-title":"Journal of the American Medical Association"},{"key":"10.1053\/bega.2000.0122_RF40","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1445-2197.1996.tb01183.x","article-title":"Incidence trends in oesophageal and proximal gastric carcinoma in Victoria","volume":"66","author":"Thomas","year":"1996","journal-title":"Australian and New Zealand Journal of Surgery"},{"key":"10.1053\/bega.2000.0122_RF41","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1056\/NEJM199903183401101","article-title":"Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma","volume":"340","author":"Lagergren","year":"1999","journal-title":"New England Journal of Medicine"},{"key":"10.1053\/bega.2000.0122_RF42","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1056\/NEJM199510263331703","article-title":"A comparison of five maintenance therapies for reflux esophagitis","volume":"333","author":"Vigneri","year":"1995","journal-title":"New England Journal of Medicine"},{"key":"10.1053\/bega.2000.0122_RF43","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/0016-5085(88)90162-X","article-title":"Healing and relapse of severe peptic esophagitis after treatment with omeprazole","volume":"95","author":"Hetzel","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF44","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3109\/00365529509101589","article-title":"Omeprazole in the long term treatment of gastro-oesophageal reflux disease","volume":"30","author":"Laursen","year":"1995","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-2036.1995.tb00779.x","article-title":"The role of proton pump inhibitors in the treatment of gastro-oesophageal reflux disease","volume":"9","author":"Bardhan","year":"1995","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2000.0122_RF46","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1016\/0016-5085(94)90532-0","article-title":"A comparison of omeprazole and ranitidine in prevention of recurrence of benign esophageal stricture","volume":"107","author":"Smith","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF47","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1136\/gut.35.5.590","article-title":"Omeprazole versus ranitidine for prevention of relapse in reflux oesophagitis. A controlled double blind trial of their efficacy and safety","volume":"35","author":"Dent","year":"1994","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF48","doi-asserted-by":"crossref","first-page":"161","DOI":"10.7326\/0003-4819-121-3-199408010-00001","article-title":"Long term treatment with omeprazole for refractory reflux esophagitis: efficacy and safety","volume":"121","author":"Klinkenberg-Knoll","year":"1994","journal-title":"Annals of Internal Medicine"},{"key":"10.1053\/bega.2000.0122_RF49","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/00042737-199802000-00004","article-title":"Gastro-oesophageal reflux disease in primary care: an international study of different treatment strategies with omeprazole","volume":"10","author":"Carlsson","year":"1998","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2000.0122_RF50","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1016\/S0016-5085(86)80017-8","article-title":"Healing and relapse of reflux esophagitis during treatment with ranitidine","volume":"91","author":"Koelz","year":"1986","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF51","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1046\/j.1365-2036.1999.00575.x","article-title":"On demand therapy of reflux oesophagitis\u2014a prospective study of symptoms, patient satisfaction and quality of life","volume":"13","author":"Wilhelmsen","year":"1999","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2000.0122_RF52","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/gut.38.4.481","article-title":"Natural history of reflux oesophagitis: a 10 year follow up of its effect on patient symptomatology and quality of life","volume":"38","author":"McDougall","year":"1996","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF53","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1136\/gut.35.1.8","article-title":"Predictive factors of the long term outcome in gastro-oesophageal reflux disease: a six year follow up of 107 patients","volume":"35","author":"Kuster","year":"1994","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF54","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1136\/gut.33.8.1016","article-title":"Three year follow up of patients with gastro-oesophageal reflux disease","volume":"33","author":"Schindlbeck","year":"1992","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF55","first-page":"37","article-title":"Natural course of gastroesophageal reflux disease: 17\u201322 year follow-up of 60 patients","volume":"92","author":"Isolauri","year":"1997","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF56","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1136\/gut.32.8.845","article-title":"Natural history of gastro-oesophageal reflux disease without oesophagitis","volume":"32","author":"Pace","year":"1991","journal-title":"Gut"},{"key":"10.1053\/bega.2000.0122_RF57","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/0016-5085(95)90373-9","article-title":"Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time","volume":"109","author":"Agreus","year":"1995","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF58","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1007\/BF02064206","article-title":"Clinical characteristics and natural history of symptomatic but not excessive gastroesophageal reflux","volume":"40","author":"Trimble","year":"1995","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2000.0122_RF59","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3109\/00365529609095544","article-title":"Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease","volume":"31","author":"Dimenas","year":"1996","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF60","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1001\/jama.1989.03430070055030","article-title":"Functional status and well being of patients with chronic conditions. Results for the Medical Outcomes Study","volume":"262","author":"Stewart","year":"1989","journal-title":"Journal of the American Medical Association"},{"key":"10.1053\/bega.2000.0122_RF61","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1097\/00000658-199606000-00006","article-title":"A physiologic approach to laparoscopic fundoplication of gastroesophageal reflux disease","volume":"223","author":"Hunter","year":"1996","journal-title":"Annals of Surgery"},{"key":"10.1053\/bega.2000.0122_RF62","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/dote\/10.1.9","article-title":"The illness behavior of patients with gastroesophageal reflux disease with and without endoscopic esophagitis","volume":"10","author":"Tew","year":"1997","journal-title":"Diseases of the Esophagus"},{"key":"10.1053\/bega.2000.0122_RF63","first-page":"19","article-title":"Quality of life during acute and intermittent treatment of gastroesophageal reflux disease with omeprazole compared with ranitidine. Results for a multi-center clinical trial","volume":"30","author":"Wiklund","year":"1998","journal-title":"Italian Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF64","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1046\/j.1365-2036.1999.00669.x","article-title":"Complete resolution of heartburn symptoms and health-related quality of life in patients with gastro-oesophageal reflux disease","volume":"13","author":"Revicki","year":"1999","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2000.0122_RF65","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1111\/j.1572-0241.1999.01206.x","article-title":"Quality of life in patients with heartburn but without esophagitis: effects of treatment with omeprazole","volume":"94","author":"Havelund","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2000.0122_RF66","doi-asserted-by":"crossref","first-page":"2123","DOI":"10.1007\/BF02071390","article-title":"Health-related quality of life of patients with acute erosive esophagitis","volume":"11","author":"Mathias","year":"1996","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2000.0122_RF67","first-page":"2500","article-title":"Health care seeking by heartburn sufferers is associated with psychosocial factors","volume":"12","author":"Johnston","year":"1996","journal-title":"American Journal of Gastroenterology"}],"container-title":["Best Practice &amp; Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691800901227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691800901227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T21:51:34Z","timestamp":1555019494000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691800901227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,10]]},"references-count":67,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,10]]}},"alternative-id":["S1521691800901227"],"URL":"https:\/\/doi.org\/10.1053\/bega.2000.0122","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2000,10]]}}}