{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T14:22:51Z","timestamp":1788790971184,"version":"build-2803163510"},"reference-count":94,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice &amp; Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1053\/bega.2001.0184","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T13:54:50Z","timestamp":1032443690000},"page":"355-370","source":"Crossref","is-referenced-by-count":103,"title":["Pharmacological and pharmacodynamic essentials of H2-receptor antagonists and proton pump inhibitors for the practising physician"],"prefix":"10.1053","volume":"15","author":[{"given":"Jia-Qing","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard H.","family":"Hunt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/bega.2001.0184_RF1","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1001\/archinte.159.7.649","article-title":"Importance of pH control in the management of GORD","volume":"159","author":"Hunt","year":"1999","journal-title":"Archives of Internal Medicine"},{"key":"10.1053\/bega.2001.0184_RF2","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1136\/gut.28.9.1120","article-title":"Acid suppression in duodenal ulcer: a meta-analysis to define optimal dosing with antisecretory drugs","volume":"28","author":"Jones","year":"1987","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0016-5085(90)91015-X","article-title":"Is there an optimal degree of acid suppression for healing of duodenal ulcers? A model of the relationship between ulcer healing and acid suppression","volume":"99","author":"Burget","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF4","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1365-2036.1990.tb00445.x","article-title":"The relationship between suppression of acidity and gastric ulcer healing rates","volume":"4","author":"Howden","year":"1990","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF5","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000200917","article-title":"Appropriate acid suppression for the management of gastro-oesophageal reflux disease","volume":"51","author":"Bell","year":"1992","journal-title":"Digestion"},{"key":"10.1053\/bega.2001.0184_RF6","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJM199803123381105","article-title":"Omeprazole compared with misoprostol for ulcers associated with nonsteroidal antiinflammatory drugs. Omeprazole versus Misoprostol for NSAID-induced Ulcer Management (OMNIUM) Study Group","volume":"338","author":"Hawkey","year":"1998","journal-title":"New England Journal of Medicine"},{"key":"10.1053\/bega.2001.0184_RF7","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/236385a0","article-title":"Definition and antagonism of histamine H2-receptors","volume":"236","author":"Black","year":"1972","journal-title":"Nature"},{"key":"10.1053\/bega.2001.0184_RF8","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/S0140-6736(74)92901-8","article-title":"Inhibition of nocturnal acid secretion in duodenal ulcer by one oral dose of metamide","volume":"i","author":"Milton-Thompson","year":"1974","journal-title":"Lancet"},{"key":"10.1053\/bega.2001.0184_RF9","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1136\/gut.24.10.904","article-title":"Single nocturnal dose of an H2-receptor antagonist for the treatment of duodenal ulcer","volume":"24","author":"Gledhill","year":"1983","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF10","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S0140-6736(85)92196-8","article-title":"Nocturnal doses of H2-receptor antagonists for duodenal ulcer","volume":"i","author":"Howden","year":"1985","journal-title":"Lancet"},{"key":"10.1053\/bega.2001.0184_RF11","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1016\/S0016-5085(98)70010-1","article-title":"Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: a controlled study in normal subjects","volume":"115","author":"Peghini","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF12","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/j.1572-0241.1998.221_a.x","article-title":"Nocturnal recovery of gastric acid secretion with twice-daily dosing of proton pump inhibitors","volume":"93","author":"Peghini","year":"1998","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF13","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1136\/gut.31.2.148","article-title":"Effect of food on H2-receptor blockade in normal subjects and duodenal ulcerations","volume":"31","author":"Merki","year":"1990","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF14","first-page":"36","article-title":"A double-blind randomized study comparing different dose regimens of H2-receptor antagonists on 24-hour gastric secretion in normal subjects and duodenal ulcer patients","volume":"82","author":"De Gara","year":"1987","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF15","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1136\/gut.25.11.1211","article-title":"Effect of no treatment, cimetidine 1g\/day, cimetidine 2g\/day and cimetidine combined with atropine on nocturnal gastric secretion in cimetidine non-responders","volume":"25","author":"Gledhill","year":"1984","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF16","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3109\/00365528609034635","article-title":"Effect of ranitidine on meal-induced gastric pepsin and acid secretion and the influence of adding ethanol to the meal","volume":"21","author":"Frislid","year":"1986","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF17","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1007\/BF02214869","article-title":"Pharmacological aspects of acid secretion","volume":"40","author":"Hirschowitz","year":"1995","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2001.0184_RF18","first-page":"159","article-title":"The effect of H2-receptor antagonists on pepsin secretion in man","volume":"173","author":"Gledhill","year":"1985","journal-title":"Progress in Clinical and Biological Research"},{"key":"10.1053\/bega.2001.0184_RF19","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1053\/gast.1997.v112.pm9178669","article-title":"Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis","volume":"112","author":"Chiba","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF20","doi-asserted-by":"crossref","first-page":"24S","DOI":"10.1007\/BF02214870","article-title":"Optimizing acid suppression for treatment of acid-related diseases","volume":"40","author":"Hunt","year":"1995","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2001.0184_RF21","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1097\/00004836-198712000-00007","article-title":"Comparison of ranitidine and cimetidine ulcer maintenance therapy","volume":"9","author":"Kurata","year":"1987","journal-title":"Journal of Clinical Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF22","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1572-0241.2000.01701.x","article-title":"Twenty-four-hour intragastric pH: tolerance within 5 days of continuous ranitidine administration","volume":"95","author":"Lachman","year":"2000","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF23","doi-asserted-by":"crossref","first-page":"954","DOI":"10.3109\/00365529609003113","article-title":"Gastro-oesophageal reflux during 3 months of therapy with ranitidine in reflux oesophagitis","volume":"31","author":"Hatlebakk","year":"1996","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF24","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0016-5085(94)94341-9","article-title":"Do continuous infusions of omeprazole and ranitidine retain their effect with prolonged dosing?","volume":"106","author":"Merki","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF25","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1136\/gut.40.1.36","article-title":"Efficacy of primed infusions with high dose ranitidine and omeprazole to maintain high intragastric pH in patients with peptic ulcer bleeding: a prospective randomised controlled study","volume":"40","author":"Labenz","year":"1997","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF26","first-page":"351","article-title":"Effect of repeated injection and continuous infusion of omeprazole and ranitidine on intragastric pH over 72 hours","volume":"94","author":"Netzer","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF27","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/0016-5085(91)90258-M","article-title":"Nocturnal intragastric acidity during and after a period of dosing with either ranitidine or omeprazole","volume":"100","author":"Prewett","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF28","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1136\/gut.32.12.1455","article-title":"Rebound intragastric hyperacidity after abrupt withdrawal of histamine H2-receptor blockade","volume":"32","author":"Nwokolo","year":"1991","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF29","first-page":"355","article-title":"Marked rebound acid hypersecretion after treatment with ranitidine","volume":"91","author":"El-Omar","year":"1996","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF30","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1111\/j.1365-2036.1991.tb00042.x","article-title":"Rebound hypersecretion after H2-antagonist withdrawal \u2013 a comparative study with nizatidine, ranitidine and famotidine","volume":"5","author":"Fullarton","year":"1991","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF31","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/gut.30.4.449","article-title":"Rebound nocturnal hypersecretion after four weeks treatment with an H2-receptor antagonist","volume":"30","author":"Fullarton","year":"1989","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF32","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1023\/A:1026652119166","article-title":"Up-regulation of H2receptor and adenylate cyclase in rabbit parietal cells during prolonged treatment with H2-receptor antagonists","volume":"44","author":"Takeuchi","year":"1999","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2001.0184_RF33","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1046\/j.1365-2036.1999.00507.x","article-title":"Low-dose ranitidine for the relief of heartburn","volume":"13","author":"Pappa","year":"1999","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF34","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1046\/j.1365-2036.1998.00384.x","article-title":"On-demand treatment of gastro-oesophageal reflux symptoms: a comparison of ranitidine 75mg with cimetidine 200mg or placebo","volume":"12","author":"Galmiche","year":"1998","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF35","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1046\/j.1365-2036.1997.00227.x","article-title":"Inhibition of intragastric acidity in healthy subjects dosed with ranitidine 75mg: a comparative study with cimetidine and placebo","volume":"11","author":"Grimley","year":"1997","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF36","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1046\/j.1365-2036.1997.00211.x","article-title":"Nocturnal intragastric acidity after over-the-counter doses of famotidine, ranitidine or placebo","volume":"11","author":"Grimley","year":"1997","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF37","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1046\/j.1365-2036.1998.00307.x","article-title":"The effects of low doses of ranitidine on intragastric acidity in healthy men","volume":"12","author":"Wyeth","year":"1998","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF38","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1046\/j.1365-2036.1998.00316.x","article-title":"Comparison of the effect of the antacid Rennie versus low-dose H2-receptor antagonists (ranitidine, famotidine) on intragastric acidity","volume":"12","author":"Netzer","year":"1998","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF39","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1001\/jama.1996.03530420056036","article-title":"Comparison of the effects of over-the-counter famotidine and calcium carbonate antacid on postprandial gastric acid. A randomized controlled trial","volume":"275","author":"Feldman","year":"1996","journal-title":"Journal of the American Medical Association"},{"key":"10.1053\/bega.2001.0184_RF40","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1046\/j.1365-2036.1999.00478.x","article-title":"Impact of food intake on the antisecretory effect of low-dose ranitidine and famotidine","volume":"13","author":"Netzer","year":"1999","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF41","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/290159a0","article-title":"Substituted benzimidazoles inhibit gastric acid secretion by blocking (H+, K+) ATPase","volume":"290","author":"Fellenius","year":"1981","journal-title":"Nature"},{"key":"10.1053\/bega.2001.0184_RF42","doi-asserted-by":"crossref","first-page":"7690","DOI":"10.1016\/S0021-9258(17)32907-1","article-title":"A nonelectrogenic H+pump in plasma membranes of hog stomach","volume":"251","author":"Sachs","year":"1976","journal-title":"Journal of Biological Chemistry"},{"key":"10.1053\/bega.2001.0184_RF43","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/j.1875-9114.1997.tb03675.x","article-title":"Proton pump inhibitors and acid-related diseases","volume":"17","author":"Sachs","year":"1997","journal-title":"Pharmacotherapy"},{"key":"10.1053\/bega.2001.0184_RF44","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2165\/00003495-199448010-00008","article-title":"Omeprazole: an update of its pharmacology and therapeutic use in acid-related disorders","volume":"48","author":"Wilde","year":"1994","journal-title":"Drug"},{"key":"10.1053\/bega.2001.0184_RF45","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2165\/00003495-199754030-00010","article-title":"Lansoprazole: an update of its pharmacological properties and clinical efficacy in the management of acid-related disorders","volume":"54","author":"Langtry","year":"1997","journal-title":"Drugs"},{"key":"10.1053\/bega.2001.0184_RF46","doi-asserted-by":"crossref","first-page":"460","DOI":"10.2165\/00003495-199651030-00012","article-title":"Pantoprazole: a review of its pharmacological properties and therapeutic use in acid-related disorders","volume":"51","author":"Fitton","year":"1996","journal-title":"Drugs"},{"key":"10.1053\/bega.2001.0184_RF47","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1136\/gut.26.6.594","article-title":"Effect of omeprazole on the secretion of intrinsic factor, gastric acid and pepsin in man","volume":"26","author":"Kittang","year":"1985","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF48","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1159\/000201233","article-title":"Influence of lansoprazole on intragastric 24-hour pH, meal-stimulated gastric acid secretion, and concentrations of gastrointestinal hormones and enzymes in serum and gastric juice in healthy volunteers","volume":"56","author":"Brunner","year":"1995","journal-title":"Digestion"},{"key":"10.1053\/bega.2001.0184_RF49","doi-asserted-by":"crossref","first-page":"91","DOI":"10.2165\/00003495-199448010-00008","article-title":"Omeprazole: an update of its pharmacology and therapeutic use in acid-related disorders","volume":"48","author":"Wilde","year":"1994","journal-title":"Drug"},{"key":"10.1053\/bega.2001.0184_RF50","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1111\/j.1365-2125.1985.tb05044.x","article-title":"Antisecretory effect and oral pharmacokinetics following low dose omeprazole in man","volume":"20","author":"Howden","year":"1985","journal-title":"British Journal of Clinical Pharmacology"},{"key":"10.1053\/bega.2001.0184_RF51","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.3109\/00365528809090202","article-title":"Relationship between reduction of gastric acid secretion and plasma gastrin concentration during omeprazole treatment","volume":"23","author":"Lind","year":"1988","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF52","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0016-5085(85)80133-5","article-title":"Omeprazole: a study of its inhibition of gastric pH and oral pharmacokinetics after morning or evening dosage","volume":"88","author":"Prichard","year":"1985","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF53","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2165\/00003088-199631010-00002","article-title":"Pharmacokinetics, metabolism and interactions of acid pump inhibitors: focus on omeprazole, lansoprazole and pantoprazole","volume":"31","author":"Andersson","year":"1996","journal-title":"Clinical Pharmacokinetics"},{"key":"10.1053\/bega.2001.0184_RF54","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/j.1365-2036.1992.tb00550.x","article-title":"Omeprazole (20mg) daily given in the morning or evening: a comparison of effects on gastric acidity, and plasma gastrin and omeprazole concentration","volume":"6","author":"Chiverton","year":"1992","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF55","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1093\/ajhp\/53.12.1401","article-title":"Lansoprazole and omeprazole in the treatment of acid peptic disorders","volume":"53","author":"Blum","year":"1996","journal-title":"American Journal of Health-System Pharmacology"},{"key":"10.1053\/bega.2001.0184_RF56","doi-asserted-by":"crossref","first-page":"458","DOI":"10.2165\/00003088-199528060-00004","article-title":"Clinical pharmacokinetics of lansoprazole","volume":"28","author":"Delhotal Landes","year":"1995","journal-title":"Clinical Pharmacokinetics"},{"key":"10.1053\/bega.2001.0184_RF57","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1007\/s002280050111","article-title":"Pharmacokinetics and absolute bioavailability of lansoprazole","volume":"50","author":"Gerloff","year":"1996","journal-title":"European Journal of Clinical Pharmacology"},{"key":"10.1053\/bega.2001.0184_RF58","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1046\/j.1365-2036.1996.103242000.x","article-title":"Time to maximize effect of lansoprazole on gastric pH in normal male volunteers","volume":"10","author":"Bell","year":"1996","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF59","doi-asserted-by":"crossref","first-page":"473","DOI":"10.2165\/00003495-199754030-00010","article-title":"Lansoprazole: an update of its pharmacological properties and clinical efficacy in the management of acid-related disorders","volume":"54","author":"Langtry","year":"1997","journal-title":"Drugs"},{"key":"10.1053\/bega.2001.0184_RF60","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1046\/j.1365-2036.1998.00306.x","article-title":"Dose\u2013response relationship of lansoprazole to gastric acid antisecretory effects","volume":"12","author":"Blum","year":"1998","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF61","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1365-2036.1989.tb00205.x","article-title":"Human gastric acid secretion following repeated doses of AG-1749","volume":"3","author":"M\u00fcller","year":"1989","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF62","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/BF01740655","article-title":"Dose ranging study of lansoprazole, a new proton pump inhibitor, in patients with high gastric acid secretion","volume":"43","author":"Berlin","year":"1992","journal-title":"European Journal of Clinical Pharmacology"},{"key":"10.1053\/bega.2001.0184_RF63","first-page":"1648","article-title":"Dosing frequency to maximum effect of lansoprazole 30mg on 24-hour intragastric pH in normal volunteers","volume":"93","author":"Sridhar","year":"1998","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF64","first-page":"489","article-title":"Effect of four lansoprazole dose levels and one dosage regimen of omeprazole on 24-hour intragastric pH in healthy subjects","volume":"17","author":"Timmer","year":"1995","journal-title":"Methods and Findings in Experimental and Clinical Pharmacology"},{"key":"10.1053\/bega.2001.0184_RF65","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1365-2036.1994.tb00293.x","article-title":"Comparison of lansoprazole with omeprazole on 24-hour intragastric pH, acid secretion and serum gastrin in healthy volunteers","volume":"8","author":"Bruley des Varannes","year":"1994","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF66","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1046\/j.1365-2036.1997.157332000.x","article-title":"Lansoprazole versus omeprazole: influence on meal-stimulated gastric acid secretion","volume":"11","author":"Dammann","year":"1997","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF67","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00004836-199703000-00003","article-title":"The effect of oral doses of lansoprazole and omeprazole on gastric pH","volume":"24","author":"Tolman","year":"1997","journal-title":"Journal of Clinical Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF68","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1080\/00365529850172304","article-title":"Comparison of the effect of lansoprazole and omeprazole on intragastric acidity and gastroesophageal reflux in patients with gastroesophageal reflux disease","volume":"33","author":"Janczewska","year":"1998","journal-title":"Scandinavian Journal of Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF69","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1046\/j.1365-2036.2000.00823.x","article-title":"Initial potency of lansoprazole and omeprazole tablets on pentagastrin-stimulated gastric acid secretion \u2013 a placebo-controlled study in healthy volunteers","volume":"14","author":"Muller","year":"2000","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF70","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1002\/j.1875-9114.1997.tb03714.x","article-title":"Lansoprazole: a comprehensive review","volume":"17","author":"Zimmermann","year":"1997","journal-title":"Pharmacotherapy"},{"key":"10.1053\/bega.2001.0184_RF71","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1365-2036.1995.tb00394.x","article-title":"Review article: the continuing development of proton pump inhibitors with particular reference to pantoprazole","volume":"9","author":"Huber","year":"1995","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF72","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2165\/00003088-199631010-00002","article-title":"Pharmacokinetics, metabolism and interactions of acid pump inhibitors: focus on omeprazole, lansoprazole and pantoprazole","volume":"31","author":"Andersson","year":"1996","journal-title":"Clinical Pharmacokinetics"},{"key":"10.1053\/bega.2001.0184_RF73","doi-asserted-by":"crossref","first-page":"S15","DOI":"10.1097\/00042737-199610001-00004","article-title":"Pantoprazole a new proton-pump inhibitor, has a precise and predictable profile of activity","volume":"8","author":"Parsons","year":"1996","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2001.0184_RF74","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1365-2036.1994.tb00239.x","article-title":"Effect of pantoprazole on 24-h intragastric pH and serum gastrin in humans","volume":"8","author":"Londong","year":"1994","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF75","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1046\/j.1365-2036.1998.00416.x","article-title":"Comparison of 24-h control of gastric acidity by three different dosages of pantoprazole in patients with duodenal ulcer","volume":"12","author":"Savarino","year":"1998","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF76","first-page":"915","article-title":"Intragastric pH and serum gastrin during administration of different doses of pantoprazole in healthy subjects","volume":"8","author":"Koop","year":"1996","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2001.0184_RF77","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1111\/j.1365-2036.1992.tb00058.x","article-title":"Effects of oral pantoprazole on 24-hour intragastric acidity and plasma gastrin profiles","volume":"6","author":"Hannan","year":"1992","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF78","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1097\/00042737-199706000-00009","article-title":"Morning and evening administration of pantoprazole: a study to compare the effect on 24-hour intragastric pH","volume":"9","author":"M\u00fcssig","year":"1997","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2001.0184_RF79","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1046\/j.1365-2036.1997.00195.x","article-title":"Treatment of reflux oesophagitis of moderate and severe grade with ranitidine or pantoprazole \u2013 comparison of 24-hour intragastric and oesophageal pH","volume":"11","author":"Armbrecht","year":"1997","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF80","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00042737-199702000-00017","article-title":"Twenty-four-hour monitoring of intragastric acidity: comparison between lansoprazole 30mg and pantoprazole 40mg","volume":"9","author":"Florent","year":"1997","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2001.0184_RF81","doi-asserted-by":"crossref","first-page":"261","DOI":"10.2165\/00003495-199855020-00009","article-title":"Rabeprazole","volume":"55","author":"Prakash","year":"1998","journal-title":"Drugs"},{"key":"10.1053\/bega.2001.0184_RF82","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1254\/fpj.102.389","article-title":"Inhibitory action of E3810 on H+, K(+)-ATPase and gastric acid secretion in vitro","volume":"102","author":"Fujisaki","year":"1993","journal-title":"Nippon Yakurigaku Zasshi"},{"key":"10.1053\/bega.2001.0184_RF83","doi-asserted-by":"crossref","first-page":"2049","DOI":"10.1016\/0006-2952(94)90504-5","article-title":"Specific proton pump inhibitors E3810 and lansoprazole affect the recovery process of gastric secretion in rats differently","volume":"48","author":"Tomiyama","year":"1994","journal-title":"Biochemical Pharmacology"},{"key":"10.1053\/bega.2001.0184_RF84","first-page":"466","article-title":"Pharmacokinetic properties of E3810, a new proton pump inhibitor, in healthy male volunteers","volume":"32","author":"Yasuda","year":"1994","journal-title":"International Journal of Clinical Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF85","article-title":"The effects of rabeprazole on 24-hour intragastric acidity and plasma gastrin concentration in healthy subjects","volume":"39","author":"Blanshard","year":"1996","journal-title":"Gut"},{"key":"10.1053\/bega.2001.0184_RF86","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1046\/j.1365-2036.2000.00774.x","article-title":"Rabeprazole produces rapid, potent, and long-acting inhibition of gastric acid secretion in subjects withHelicobacter pylori infection","volume":"14","author":"Ohning","year":"2000","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF87","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1046\/j.1365-2036.1999.00545.x","article-title":"The effects of oral rabeprazole on endocrine and gastric secretory function in healthy volunteers","volume":"13","author":"Dammann","year":"1999","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF88","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1046\/j.1365-2036.1997.00244.x","article-title":"Effects of oral rabeprazole on oesophageal and gastric pH in patients with gastro-oesophageal reflux disease","volume":"11","author":"Robinson","year":"1997","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF89","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1046\/j.1365-2036.1998.00418.x","article-title":"A placebo-controlled trial to assess the effects of 8 days of dosing with rabeprazole versus omeprazole on 24-h intragastric acidity and plasma gastrin concentrations in young healthy male subjects","volume":"12","author":"Williams","year":"1998","journal-title":"Alimentary Pharmacology and Therapeutics"},{"key":"10.1053\/bega.2001.0184_RF90","doi-asserted-by":"crossref","first-page":"321","DOI":"10.2165\/00003495-200060020-00006","article-title":"Esomeprazole","volume":"60","author":"Spencer","year":"2000","journal-title":"Drugs"},{"key":"10.1053\/bega.2001.0184_RF91","unstructured":"R\u00f6haa, K, Lundin, C, Rydholm, H, Esomeprazole 40mg provides more effective acid control than omeprazole 40mg, Guteborg, Sweden"},{"key":"10.1053\/bega.2001.0184_RF92","doi-asserted-by":"crossref","first-page":"A22","DOI":"10.1016\/S0016-5085(00)82157-5","article-title":"Esomeprazole (E) 40mg provides more effective acid control than pantoprazole (P) 40mg","volume":"118","author":"Wilder-Smith","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF93","doi-asserted-by":"crossref","first-page":"A20","DOI":"10.1016\/S0016-5085(00)82149-6","article-title":"Esomeprazole 40mg provides more effective acid control than lansoprazole 30mg","volume":"118","author":"R\u00f6haa","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2001.0184_RF94","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1046\/j.1365-2036.2000.00813.x","article-title":"Esomeprazole provides improved acid control vs. omeprazole in patients with symptoms of gastro-oesophageal reflux disease","volume":"14","author":"Lind","year":"2000","journal-title":"Alimentary Pharmacology and Therapeutics"}],"container-title":["Best Practice &amp; Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691801901842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691801901842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T22:15:26Z","timestamp":1704320126000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691801901842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":94,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["S1521691801901842"],"URL":"https:\/\/doi.org\/10.1053\/bega.2001.0184","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}