{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T15:55:04Z","timestamp":1777823704651,"version":"3.51.4"},"reference-count":118,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T00:00:00Z","timestamp":1033430400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Best Practice &amp; Research Clinical Gastroenterology"],"published-print":{"date-parts":[[2002,10]]},"DOI":"10.1053\/bega.2002.0326","type":"journal-article","created":{"date-parts":[[2002,10,28]],"date-time":"2002-10-28T17:40:27Z","timestamp":1035826827000},"page":"691-707","source":"Crossref","is-referenced-by-count":50,"title":["Pathology of steatohepatitis"],"prefix":"10.1053","volume":"16","author":[{"given":"Elizabeth M.","family":"Brunt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dina G.","family":"Tiniakos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/bega.2002.0326_RF1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1055\/s-2007-1007111","article-title":"Nonalcoholic steatohepatitis","volume":"19","author":"Diehl","year":"1999","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF2","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0025-6196(24)00530-5","article-title":"Nonalcoholic steatohepatitis. Mayo Clinic experiences with a hitherto unnamed disease","volume":"55","author":"Ludwig","year":"1980","journal-title":"Mayo Clinic Proceedings"},{"key":"10.1053\/bega.2002.0326_RF3","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1053\/gast.2001.27126","article-title":"Nonalcoholic steatohepatitis","volume":"121","author":"Reid","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF4","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/lt.500030303","article-title":"Alcoholic liver disease: natural history","volume":"3","author":"Diehl","year":"1997","journal-title":"Liver Transplantation and Surgery"},{"key":"10.1053\/bega.2002.0326_RF5","series-title":"Pathology of the Liver","first-page":"317","article-title":"Alcoholic liver disease","author":"de la Hall","year":"1994"},{"key":"10.1053\/bega.2002.0326_RF6","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1016\/S0016-5085(99)70506-8","article-title":"Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity","volume":"116","author":"Matteoni","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF7","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0002-9343(99)00271-5","article-title":"Association of nonalcoholic fatty liver disease with insulin resistance","volume":"107","author":"Marchesini","year":"1999","journal-title":"American Journal of Medicine"},{"key":"10.1053\/bega.2002.0326_RF8","doi-asserted-by":"crossref","first-page":"3379","DOI":"10.1111\/j.1572-0241.1999.03379.x","article-title":"Subacute severe steatohepatitis during prednisolone therapy for systemic lupus erythematosus","volume":"94","author":"Nanki","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF9","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0140-6736(05)74872-8","article-title":"Cirrhosis with steatohepatitis after adjuvant tamoxifen","volume":"353","author":"Oien","year":"1999","journal-title":"Lancet"},{"key":"10.1053\/bega.2002.0326_RF10","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1016\/S0140-6736(99)00163-4","article-title":"Non-alcoholic steatohepatitis: another disease of affluence","volume":"353","author":"James","year":"1999","journal-title":"Lancet"},{"key":"10.1053\/bega.2002.0326_RF11","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1478-3231.1999.tb00053.x","article-title":"Nonalcoholic steatohepatitis. A toxic liver disease in industrial workers","volume":"19","author":"Cotrim","year":"1999","journal-title":"Liver"},{"key":"10.1053\/bega.2002.0326_RF12","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.2337\/diabetes.50.8.1844","article-title":"Nonalcoholic fatty liver disease: a feature of the metabolic syndome","volume":"50","author":"Marchesini","year":"2001","journal-title":"Diabetes"},{"key":"10.1053\/bega.2002.0326_RF13","first-page":"98","article-title":"Non-alcoholic steatohepatitis: association with obesity and insulin resistance, and influence of weight loss","volume":"26","author":"Luyckx","year":"2000","journal-title":"Diabetes and Metabolism"},{"key":"10.1053\/bega.2002.0326_RF14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1055\/s-2001-12927","article-title":"Etiopathogenesis of nonalcoholic steatohepatitis","volume":"21","author":"Chitturi","year":"2001","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF15","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1572-0241.2001.03548.x","article-title":"Insulin resistance and nonalcoholic steatohepatitis: fat or fiction?","volume":"96","author":"Sanyal","year":"2001","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF16","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S1590-8658(01)80091-8","article-title":"Insulin resistance in non-alcoholic steatohepatitis","volume":"33","author":"Comert","year":"2001","journal-title":"Digestive Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF17","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1055\/s-2001-12926","article-title":"Clinical features and natural history of nonalcoholic steatosis syndromes","volume":"21","author":"Falck-Ytter","year":"2001","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF18","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/S0016-5085(00)70189-2","article-title":"NASH: can we iron out the pathogenesis? Selected summary","volume":"118","author":"Blendis","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF19","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0168-8278(99)80032-4","article-title":"Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis","volume":"31","author":"Bonkovsky","year":"1999","journal-title":"J Hepatol"},{"key":"10.1053\/bega.2002.0326_RF20","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1002\/hep.1840210636","article-title":"Nonalcoholic steatohepatitis: tightening the morphologic screws on a hepatic ramber","volume":"21","author":"Lee","year":"1995","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF21","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1055\/s-2001-12925","article-title":"Nonalcoholic steatohepatitis: definition and pathology","volume":"21","author":"Brunt","year":"2001","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF22","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/0002-9343(79)90740-X","article-title":"Fatty liver hepatitis and cirrhosis in obese patients","volume":"67","author":"Adler","year":"1979","journal-title":"American Journal of Medicine"},{"key":"10.1053\/bega.2002.0326_RF23","first-page":"650","article-title":"Comparison between nonalcoholic steatohepatitis and alcoholic hepatitis","volume":"82","author":"Itoh","year":"1987","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF24","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/path.1711560210","article-title":"The pathology of diabetic hepatitis","volume":"156","author":"Nagore","year":"1988","journal-title":"Journal of Pathology"},{"key":"10.1053\/bega.2002.0326_RF25","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1016\/0016-5085(88)90183-7","article-title":"Alcohollike liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury","volume":"95","author":"Diehl","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF26","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/0046-8177(89)90249-9","article-title":"Nonalcoholic steatohepatitis: a study of 49 patients","volume":"20","author":"Lee","year":"1989","journal-title":"Human Pathology"},{"key":"10.1053\/bega.2002.0326_RF27","first-page":"69","article-title":"Subcapsular steatonecrosis in response to peritoneal insulin delivery: a clue to the pathogenesis of steatonecrosis in obesity","volume":"2","author":"Wanless","year":"1989","journal-title":"Modern Pathology"},{"key":"10.1053\/bega.2002.0326_RF28","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/hep.1840110114","article-title":"The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years","volume":"11","author":"Powell","year":"1990","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF29","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/0016-5085(94)90235-6","article-title":"Nonalcoholic steatohepatitis: an expanded clinical entity","volume":"107","author":"Bacon","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF30","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/S0022-3476(95)70156-7","article-title":"Idiopathic steatohepatitis in childhood: a multicenter retrospective study","volume":"127","author":"Baldridge","year":"1995","journal-title":"Journal of Pediatrics"},{"key":"10.1053\/bega.2002.0326_RF31","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/BF02208601","article-title":"Nonalcoholic steatohepatitis clinicopathologic comparison with alcoholic hepatitis in ambulatory and hospitalized patients","volume":"41","author":"Pinto","year":"1996","journal-title":"Digestive Diseases and Sciences"},{"key":"10.1053\/bega.2002.0326_RF32","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1111\/j.1572-0241.1999.01377.x","article-title":"Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions","volume":"94","author":"Brunt","year":"1999","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF33","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/00005176-200001000-00017","article-title":"Nonalcoholic steatohepatitis in children","volume":"30","author":"Rashid","year":"2000","journal-title":"Journal of Pediatric Gastroenterology and Nutrition"},{"key":"10.1053\/bega.2002.0326_RF34","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1002\/hep.510300604","article-title":"Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis","volume":"30","author":"Angulo","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF35","first-page":"246","article-title":"Diagnosis and interpretation of steatosis and steatohepatitis","volume":"15","author":"Burt","year":"1998","journal-title":"Seminars in Diagnostic Pathology"},{"key":"10.1053\/bega.2002.0326_RF36","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1002\/hep.510290347","article-title":"Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease","volume":"29","author":"Caldwell","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF37","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1053\/jhep.2000.17894","article-title":"Prevalence of obesity and diabetes in patients with cryptogenic cirrhosis: a case control study","volume":"34","author":"Pooawala","year":"2000","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF38","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1600-0676.1987.tb00366.x","article-title":"Ultrastructural findings on polymorphonuclear leucocyte infiltration and acute hepatocellular damage in alcoholic hepatitis","volume":"7","author":"Takahashi","year":"1987","journal-title":"Liver"},{"key":"10.1053\/bega.2002.0326_RF39","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/S0168-8278(00)00089-1","article-title":"Hepatocyte apoptosis is a pathologic feature of human alcoholic hepatitis","volume":"34","author":"Natori","year":"2001","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF40","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0168-8278(00)00047-7","article-title":"Clinical and biological relevance of hepatocyte apoptosis in alcoholic hepatitis","volume":"34","author":"Ziol","year":"2001","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF41","series-title":"Diagnostic Liver Pathology","article-title":"Fatty change and steatohepatitis","author":"Lee","year":"1995"},{"key":"10.1053\/bega.2002.0326_RF42","doi-asserted-by":"crossref","first-page":"476","DOI":"10.5694\/j.1326-5377.2000.tb139299.x","article-title":"Non-alcoholic steatohepatitis in children and adults","volume":"173","author":"Manton","year":"2000","journal-title":"Medical Journal of Australia"},{"key":"10.1053\/bega.2002.0326_RF43","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0002-9343(99)00315-0","article-title":"Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds","volume":"108","author":"Struben","year":"2000","journal-title":"American Journal of Medicine"},{"key":"10.1053\/bega.2002.0326_RF44","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1055\/s-2008-1040605","article-title":"Histologic spectrum of alcoholic liver disease","volume":"6","author":"MacSween","year":"1986","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF45","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1055\/s-2007-1007346","article-title":"Pathology of alcoholic liver disease","volume":"13","author":"French","year":"1993","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF46","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0168-8278(00)80233-0","article-title":"Mallory bodies revisited","volume":"32","author":"Denk","year":"2000","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF47","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/S0002-9440(10)64997-8","article-title":"Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies","volume":"156","author":"Zatloukal","year":"2000","journal-title":"American Journal of Pathology"},{"key":"10.1053\/bega.2002.0326_RF48","first-page":"461A","article-title":"The distribution of mitochondria containing crystalline inclusions within the hepatic lobule in NASH","volume":"34","author":"Le","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF49","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S0168-8278(99)80033-6","article-title":"Mitochondrial abnormalities in non-alcoholic steatohepatitis","volume":"31","author":"Caldwell","year":"1999","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF50","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1053\/gast.2001.23256","article-title":"Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities","volume":"120","author":"Sanyal","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF51","series-title":"Liver Biopsy Interpretation","first-page":"111","article-title":"Fatty liver and lesions in the alcoholic","author":"Lefkowitch","year":"1994"},{"key":"10.1053\/bega.2002.0326_RF52","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S0168-8278(96)80238-8","article-title":"Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis","volume":"75","author":"Reeves","year":"1996","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF53","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1053\/hupa.2000.8440","article-title":"Hepatic stellate cell activation in non-alcoholic steatohepatitis and fatty liver","volume":"31","author":"Washington","year":"2000","journal-title":"Human Pathology"},{"key":"10.1053\/bega.2002.0326_RF54","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1478-3231.1999.tb00047.x","article-title":"Nonalcoholic steatohepatitis (NASH): further expansion of this clinical entity?","volume":"19","author":"Brunt","year":"1999","journal-title":"Liver"},{"key":"10.1053\/bega.2002.0326_RF55","first-page":"707","article-title":"Alcoholic liver disease: morphological manifestations. Review by an international group","volume":"1","author":"Baptista","year":"1981","journal-title":"Lancet"},{"key":"10.1053\/bega.2002.0326_RF56","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0016-5085(98)70482-2","article-title":"Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis","volume":"114","author":"George","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF57","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/hep.510300407","article-title":"Hepatic iron and nonalcoholic fatty liver disease","volume":"30","author":"Younossi","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF58","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1053\/gast.2001.21913","article-title":"Hemochromatosis: diagnosis and management","volume":"120","author":"Bacon","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF59","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1111\/j.1440-1746.1997.tb00450.x","article-title":"Review: nonalcoholic steatohepatitis","volume":"12","author":"Ludwig","year":"1997","journal-title":"Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2002.0326_RF60","series-title":"Differential Diagnosis in Pathology: Liver Disorders","first-page":"24","article-title":"Alcoholic hepatitis vs nonalcoholic steatohepatitis","author":"Thung","year":"1995"},{"key":"10.1053\/bega.2002.0326_RF61","first-page":"69","article-title":"Cirrhosis of the liver, five different types of lesions from which it may arise","volume":"22","author":"Mallory","year":"1911","journal-title":"Bulletin of John's Hopkins Hospital"},{"key":"10.1053\/bega.2002.0326_RF62","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/S0016-5085(19)33180-4","article-title":"Natural history of alcoholic hepatitis III: histologic changes","volume":"63","author":"Galambos","year":"1972","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF63","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0016-5085(82)80007-3","article-title":"Occlusive venous lesions in alcoholic liver disease","volume":"83","author":"Goodman","year":"1982","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF64","doi-asserted-by":"crossref","first-page":"646","DOI":"10.7326\/0003-4819-59-5-646","article-title":"Sclerosing hyaline necrosis in the liver of the chronic alcoholic. A recognizable lesion","volume":"59","author":"Edmondson","year":"1963","journal-title":"Annals of Internal Medicine"},{"key":"10.1053\/bega.2002.0326_RF65","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/0168-8278(95)80057-3","article-title":"Early perivenular fibrogenesis \u2013 precirrhotic lesions among moderate alcohol consumers and chronic alcoholics","volume":"23","author":"Savolainen","year":"1995","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF66","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1136\/jcp.39.1.63","article-title":"Hepatic vein lesions in alcoholic liver disease: retrospective biopsy and necropsy study","volume":"39","author":"Burt","year":"1986","journal-title":"Journal of Clinical Pathology"},{"key":"10.1053\/bega.2002.0326_RF67","first-page":"269","article-title":"The intestinal and liver complications of diabetes mellitus","volume":"38","author":"Falchuk","year":"1993","journal-title":"Advances in Internal Medicine"},{"key":"10.1053\/bega.2002.0326_RF68","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1016\/S0168-8278(00)80301-3","article-title":"Characterization of pathogenetic and prognostic factors of nonalcoholic steatohepatitis associated with obesity","volume":"33","author":"Garcia-Monzon","year":"2000","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF69","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/ajcp\/66.4.684","article-title":"Hepatic lesions of central pericellular fibrosis in morbid obesity and after jejunoileal bypass","volume":"66","author":"Marubbio","year":"1976","journal-title":"American Journal of Clinical Pathology"},{"key":"10.1053\/bega.2002.0326_RF70","first-page":"1349","article-title":"Liver pathology in morbidly obese patients with and without diabetes","volume":"85","author":"Silverman","year":"1990","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF71","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0016-5085(00)70364-7","article-title":"Liver fibrosis in overweight patients","volume":"118","author":"Ratziu","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF72","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1002\/hep.1840120505","article-title":"Fatty liver hepatitis (steatohepatitis) and obesity: an autopsy study with analysis of risk factors","volume":"12","author":"Wanless","year":"1990","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF73","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1055\/s-2008-1041754","article-title":"Diabetes mellitus and the liver","volume":"5","author":"Stone","year":"1985","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF74","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/S0046-8177(87)80050-3","article-title":"Perisinusoidal fibrosis and basement membrane-like material in the livers of diabetic patients","volume":"18","author":"Latry","year":"1987","journal-title":"Human Pathology"},{"key":"10.1053\/bega.2002.0326_RF75","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/0168-8278(91)90942-5","article-title":"Hepatic effects of dietary weight loss in morbidly obese subjects","volume":"12","author":"Andersen","year":"1991","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF76","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1093\/ajcp\/63.3.318","article-title":"Post-jejunoileal bypass hepatic disease. Its similarity to alcoholic liver disease","volume":"63","author":"Peters","year":"1975","journal-title":"American Journal of Clinical Pathology"},{"key":"10.1053\/bega.2002.0326_RF77","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1600-0676.1987.tb00355.x","article-title":"Pattern of progression in liver injury following jejunoileal bypass for morbid obesity","volume":"7","author":"Vyberg","year":"1987","journal-title":"Liver"},{"key":"10.1053\/bega.2002.0326_RF78","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0046-8177(90)90076-H","article-title":"Histopathologic analysis of suspected amiodarone hepatotoxicity","volume":"21","author":"Lewis","year":"1990","journal-title":"Human Pathology"},{"key":"10.1053\/bega.2002.0326_RF79","first-page":"71","article-title":"Acute amiodarone-induced hepatitis","volume":"38","author":"Kalantzis","year":"1991","journal-title":"Hepato-Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF80","series-title":"Steato-hepatitis (NASH and ASH), Falk Symposium 121","first-page":"26","article-title":"Nonalcoholic steatohepatitis: grading and staging the histological lesions","author":"Brunt","year":"2001"},{"key":"10.1053\/bega.2002.0326_RF81","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1002\/hep.510310136","article-title":"Grading and staging the histopathological lesions of chronic hepatitis: the Knodell Activity Index and beyond","volume":"31","author":"Brunt","year":"2000","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF82","first-page":"560","article-title":"Nonalcoholic fatty liver disease: assessment of variability in pathologic interpretations","volume":"11","author":"Younossi","year":"1998","journal-title":"Modern Pathology"},{"key":"10.1053\/bega.2002.0326_RF83","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/0168-8278(95)80226-6","article-title":"Histological grading and staging of chronic hepatitis","volume":"22","author":"Ishak","year":"1995","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF84","first-page":"1061A","article-title":"Can steatohepatitis coexist with other forms of chronic liver disease?","volume":"13","author":"Brunt","year":"2000","journal-title":"Modern Pathology"},{"key":"10.1053\/bega.2002.0326_RF85","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1034\/j.1600-0676.2001.021004266.x","article-title":"Chronic hepatitis C superimposed nonalcoholic fatty liver disease","volume":"21","author":"Ong","year":"2001","journal-title":"Liver"},{"key":"10.1053\/bega.2002.0326_RF86","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S1590-8658(01)80144-4","article-title":"Concurrent non-alcoholic steatohepatitis and psoriasis. Report of three cases from the POLI.St.E.N.A. study","volume":"33","author":"Lonardo","year":"2001","journal-title":"Digestive and Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF87","first-page":"1219","article-title":"Antibody to hepatitis C is common among patients with alcoholic liver disease with and without risk factors","volume":"86","author":"Caldwell","year":"1991","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF88","first-page":"331","article-title":"Liver biopsy findings in patients with alcoholic liver disease complicated by chronic hepatitis C virus infection","volume":"7","author":"Kyriacou","year":"1995","journal-title":"European Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2002.0326_RF89","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1001\/archinte.153.8.965","article-title":"Hepatitis C virus antibody in alcoholic patients. Association with the presence of portal and\/or lobular hepatitis","volume":"153","author":"Rosman","year":"1993","journal-title":"Archives of Internal Medicine"},{"key":"10.1053\/bega.2002.0326_RF90","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1600-0676.1995.tb00689.x","article-title":"A histopathological study of alcoholics with chronic hepatitis C infection: comparison with chronic hepatitis C and alcoholic liver disease","volume":"15","author":"Uchimura","year":"1995","journal-title":"Liver"},{"key":"10.1053\/bega.2002.0326_RF91","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1440-1746.1996.tb00059.x","article-title":"Chronic liver disease: do alcohol and hepatitis C virus interact?","volume":"11","author":"Cooksley","year":"1996","journal-title":"Journal of Gastroenterology and Hepatology"},{"key":"10.1053\/bega.2002.0326_RF92","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0168-8278(00)00096-9","article-title":"Steatosis and chronic hepatitis C: an analysis of fibrosis and stellate cell activation","volume":"34","author":"Clouston","year":"2001","journal-title":"Journal of Hepatology"},{"key":"10.1053\/bega.2002.0326_RF93","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1097\/00004836-199710000-00012","article-title":"Nonalcoholic steatohepatitis masquerading as autoimmune hepatitis","volume":"25","author":"Tajiri","year":"1997","journal-title":"Journal of Clinical Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF94","doi-asserted-by":"crossref","first-page":"112S","DOI":"10.1111\/j.1530-0277.2000.tb00024.x","article-title":"Contribution of hepatitis C virus to the progression of alcoholic liver disease","volume":"24","author":"Tanaka","year":"2000","journal-title":"Alcoholism, Clinical and Experimental Research"},{"key":"10.1053\/bega.2002.0326_RF95","first-page":"11","article-title":"Hepatitis B virus and alcoholism. A puzzling association","volume":"18","author":"Nalpas","year":"1988","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF96","doi-asserted-by":"crossref","first-page":"156S","DOI":"10.1097\/00000374-199803001-00017","article-title":"Hepatitis G virus infection in patients with alcoholic liver disease","volume":"22","author":"Sobue","year":"1998","journal-title":"Alcoholism, Clinical and Experimental Research"},{"key":"10.1053\/bega.2002.0326_RF97","doi-asserted-by":"crossref","first-page":"953","DOI":"10.7326\/0003-4819-130-12-199906150-00002","article-title":"HFE genotype in patients with hemochromatosis and other liver diseases","volume":"130","author":"Bacon","year":"1999","journal-title":"Annals of Internal Medicine"},{"key":"10.1053\/bega.2002.0326_RF98","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1055\/s-2007-1007222","article-title":"A 49-year-old man with alpha 1-antitrypsin deficiency and abnormal iron study results","volume":"16","author":"Brunt","year":"1996","journal-title":"Seminars in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF99","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1053\/jhep.2001.0103306le01","article-title":"Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States","volume":"33","author":"Mehta","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF100","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/hep.510290235","article-title":"Association of diabetes mellitus and chronic hepatitis C virus infection","volume":"29","author":"Mason","year":"1999","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF101","first-page":"457A","article-title":"The impact of nonalcoholic fatty liver disease on the progression of hepatitis C","volume":"34","author":"Contos","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF102","first-page":"424A","article-title":"Association of liver steatosis and chronic hepatitis C","volume":"34","author":"Li","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF103","first-page":"221A","article-title":"The intrazonal distribution of steatosis in chronic hepatitis C and the impact of hepatic steatosis on fibrosis and necroinflammatory activity","volume":"34","author":"Fiel","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF104","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1002\/hep.1840150402","article-title":"The pathology of hepatitis C","volume":"15","author":"Scheuer","year":"1992","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF105","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1002\/hep.1840220616","article-title":"The natural history of nonalcoholic fatty liver: a follow-up study","volume":"22","author":"Teli","year":"1995","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF106","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/S0140-6736(95)91685-7","article-title":"Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver","volume":"346","author":"Teli","year":"1995","journal-title":"Lancet"},{"key":"10.1053\/bega.2002.0326_RF107","first-page":"283","article-title":"Nonalcoholic fatty liver disease","volume":"8","author":"Schaffner","year":"1986","journal-title":"Progress in Liver Disease"},{"key":"10.1053\/bega.2002.0326_RF108","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1053\/jlts.2001.23011","article-title":"Development of nonalcoholic fatty liver disease after liver transplantation for cryptogenic cirrhosis","volume":"7","author":"Contos","year":"2001","journal-title":"Liver Transplantation"},{"key":"10.1053\/bega.2002.0326_RF109","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1046\/j.1440-1827.2001.01174.x","article-title":"Hepatocellular carcinoma arising in non-alcoholic steatohepatitis","volume":"51","author":"Zen","year":"2001","journal-title":"Pathology International"},{"key":"10.1053\/bega.2002.0326_RF110","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.1111\/j.1572-0241.2000.03241.x","article-title":"Nonalcoholic steatohepatitis and hepatocellular carcinoma: natural history? (Letter)","volume":"95","author":"Cotrim","year":"2000","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF111","first-page":"557","article-title":"Who gets alcoholic liver disease: nature or nurture?","volume":"34","author":"Day","year":"2000","journal-title":"Journal of the Royal College of Physicians, London"},{"key":"10.1053\/bega.2002.0326_RF112","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1053\/jhep.2001.24236","article-title":"Promoter polymorphism of the CD 14 endotoxin receptor gene as a risk factor for alcoholic liver disease","volume":"33","author":"Jarvelainen","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/bega.2002.0326_RF113","first-page":"210","article-title":"Prognostic factors in alcoholic liver disease","volume":"86","author":"Chedid","year":"1991","journal-title":"American Journal of Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF114","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/0016-5085(87)90861-4","article-title":"Prognosis of alcoholic cirrhosis in the presence and absence of alcoholic hepatitis","volume":"92","author":"Orrego","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF115","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0140-6736(84)90295-2","article-title":"Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis","volume":"ii","author":"Sorensen","year":"1984","journal-title":"Lancet"},{"key":"10.1053\/bega.2002.0326_RF116","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0140-6736(94)92025-7","article-title":"Hepatocyte proliferation as an indicator of outcome in acute alcoholic hepatitis","volume":"343","author":"Fang","year":"1994","journal-title":"Lancet"},{"key":"10.1053\/bega.2002.0326_RF117","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1053\/gast.2001.25540","article-title":"Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese","volume":"121","author":"Dixon","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1053\/bega.2002.0326_RF118","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1053\/jhep.2001.28055","article-title":"High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: a potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis","volume":"34","author":"Paradis","year":"2001","journal-title":"Hepatology"}],"container-title":["Best Practice &amp; Research Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691802903264?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521691802903264?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T22:24:58Z","timestamp":1733869498000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521691802903264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,10]]},"references-count":118,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,10]]}},"alternative-id":["S1521691802903264"],"URL":"https:\/\/doi.org\/10.1053\/bega.2002.0326","relation":{},"ISSN":["1521-6918"],"issn-type":[{"value":"1521-6918","type":"print"}],"subject":[],"published":{"date-parts":[[2002,10]]}}}