{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T16:52:20Z","timestamp":1761843140233},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Aims<\/jats:p>\n               <jats:p>Various mode-switching algorithms are available with different tachyarrhythmia detection criteria to be satisfied to initiate mode-switching. This study evaluated three different mode-switching algorithms in patients with paroxysmal atrial fibrillation.<\/jats:p>\n               <jats:p>Methods and Results<\/jats:p>\n               <jats:p>Seventeen patients completed the study. Three mode-switching algorithms were downloaded as software into the pacemaker, each for 1 month in a single-blind, randomized sequence. The criteria to initiate mode-switching were: mean atrial rate (\u2018standard\u2019), \u20184-of-7\u2019 or \u20181-of-1\u2019 atrial intervals to exceed the atrial detection rate. Symptoms for each were measured using the Symptom Checklist\u2013Frequency and Severity index.<\/jats:p>\n               <jats:p>The median number of mode-switch episodes increased from 20 for \u2018standard\u2019 to 39 for \u20184-of-7\u2019 (P=0\u00b7029 vs \u2018standard\u2019) and 103 for \u20181-of-1\u2019 (P=0\u00b70012 vs \u2018standard\u2019) onset criteria. Median duration of episodes decreased from 2\u00b75\u2009min with \u2018standard\u2019 to 1\u00b74\u2009min with \u20184-of-7\u2019 and 0\u00b74\u2009min with \u20181-of-1\u2019 onset criteria. Frequency of symptoms was lower using \u20184-of-7\u2019 (18\u00b72\u00b112\u00b70 vs 23\u00b112\u00b70, P=0\u00b708) or \u20181-of-1\u2019 (20\u00b74\u00b112\u00b74 vs 23\u00b112\u00b70, P=0\u00b707) than \u2018standard\u2019 onset criteria. Severity of arrhythmia tended to be less with either \u20184-of-7\u2019 (16\u00b110\u00b74 vs 19\u00b71\u00b119\u00b74, P=0\u00b712) or \u20181-of-1\u2019 (17\u00b75\u00b110\u00b73 vs 19\u00b71\u00b19\u00b74, P=0\u00b718) than with \u2018standard\u2019 onset criteria.<\/jats:p>\n               <jats:p>Conclusions<\/jats:p>\n               <jats:p>The more sensitive onset criteria for detection of atrial tachyarrhythmias were associated with lower frequency and severity of symptoms.<\/jats:p>","DOI":"10.1053\/eupc.1998.0012","type":"journal-article","created":{"date-parts":[[2003,7,22]],"date-time":"2003-07-22T20:16:03Z","timestamp":1058904963000},"page":"49-54","source":"Crossref","is-referenced-by-count":12,"title":["Mode switching in dual chamber pacemakers"],"prefix":"10.1093","volume":"1","author":[{"given":"H.J.","family":"Marshall","sequence":"first","affiliation":[{"name":"University of Birmingham, Birmingham, 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