{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:10:19Z","timestamp":1791141019834,"version":"4.1.0"},"reference-count":65,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,2,1]],"date-time":"2001-02-01T00:00:00Z","timestamp":980985600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2001,2]]},"DOI":"10.1053\/gast.2001.21204","type":"journal-article","created":{"date-parts":[[2005,7,29]],"date-time":"2005-07-29T17:58:00Z","timestamp":1122659880000},"page":"346-353","source":"Crossref","is-referenced-by-count":131,"title":["Abnormal von Willebrand factor in bleeding angiodysplasias of the digestive tract"],"prefix":"10.1053","volume":"120","author":[{"given":"Agn\u00e8s","family":"Veyradier","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Balian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martine","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Giraud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Montembault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadette","family":"Obert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim","family":"Dagher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Chaput","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Naveau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/gast.2001.21204_bib1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1097\/00005792-198101000-00004","article-title":"Arteriovenous malformations of the bowel. Analysis of 22 cases and review of the literature","volume":"60","author":"Meyer","year":"1981","journal-title":"Medicine"},{"key":"10.1053\/gast.2001.21204_bib2","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1056\/NEJM199510053331407","article-title":"Hereditary hemorrhagic telangiectasia","volume":"333","author":"Guttmacher","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.21204_bib3","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0016-5085(77)80149-2","article-title":"On the nature and etiology of vascular ectasias of the colon. Degenerative lesions of aging","volume":"72","author":"Boley","year":"1977","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.21204_bib4","first-page":"807","article-title":"Angiodysplasia of the gastrointestinal tract","volume":"88","author":"Foutch","year":"1993","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.21204_bib5","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1001\/archinte.1995.00430080037005","article-title":"Angiodysplasia and lower gastrointestinal tract bleeding in elderly patients","volume":"155","author":"Sharma","year":"1995","journal-title":"Arch Intern Med"},{"key":"10.1053\/gast.2001.21204_bib6","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1007\/BF01296266","article-title":"Angiodys-plasia: clinical presentation and colonic diagnosis","volume":"29","author":"Richter","year":"1984","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2001.21204_bib7","first-page":"127","article-title":"Angiodysplasia of the colon: an expression of occlusive vascular disease","volume":"34","author":"Heer","year":"1987","journal-title":"Hepatogastroenterology"},{"key":"10.1053\/gast.2001.21204_bib8","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1055\/s-2007-1018495","article-title":"Angiodysplasia in the colon and rectum. Endoscopic morphology, localization and frequency","volume":"17","author":"Hochter","year":"1985","journal-title":"Endoscopy"},{"key":"10.1053\/gast.2001.21204_bib9","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1007\/BF01649509","article-title":"Angiodysplasia: an uncommon cause of colonic bleeding: colonoscopic evaluation of 1050 patients with rectal bleeding and anemia","volume":"2","author":"Danesh","year":"1987","journal-title":"Int J Colorectal Dis"},{"key":"10.1053\/gast.2001.21204_bib10","first-page":"62","article-title":"A prospective study of bidirectional endoscopy (colonoscopy and upper endoscopy) in the evaluation of patients with occult gastrointestinal bleeding","volume":"87","author":"Zuckerman","year":"1992","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.21204_bib11","first-page":"135","article-title":"Severe aortic stenosis in a patient with recurrent gastrointestinal bleeding\u2014replacement of the aortic valve with a porcine xenograft","volume":"75","author":"Boyle","year":"1981","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.21204_bib12","first-page":"1297","article-title":"Angiodysplasia in patients with renal insufficiency","volume":"84","author":"Navab","year":"1989","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.21204_bib13","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1055\/s-0038-1649623","article-title":"International survey of patients with von Willebrand disease and angiodysplasia","volume":"70","author":"Fressinaud","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib14","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1055\/s-0038-1642471","article-title":"A revised classification of von Willebrand disease","volume":"71","author":"Sadler","year":"1994","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib15","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1146\/annurev.biochem.67.1.395","article-title":"Biochemistry and genetics of von Willebrand factor","volume":"67","author":"Sadler","year":"1998","journal-title":"Annu Rev Biochem"},{"key":"10.1053\/gast.2001.21204_bib16","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1055\/s-0038-1646168","article-title":"von Willebrand factor: structure and function","volume":"70","author":"Meyer","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib17","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1172\/JCI115376","article-title":"Heterogeneity of plasma von Willebrand factor multimers resulting from proteolysis of the constituent subunit","volume":"88","author":"Dent","year":"1991","journal-title":"J Clin Invest"},{"key":"10.1053\/gast.2001.21204_bib18","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1056\/NEJM199811263392202","article-title":"von Willebrand factor\u2013cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome","volume":"339","author":"Furlan","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.21204_bib19","doi-asserted-by":"crossref","first-page":"1456","DOI":"10.1172\/JCI112736","article-title":"Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress\u2013induced platelet aggregation","volume":"78","author":"Moake","year":"1986","journal-title":"J Clin Invest"},{"key":"10.1053\/gast.2001.21204_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00005792-199701000-00001","article-title":"von Willebrand disease","volume":"76","author":"Nichols","year":"1997","journal-title":"Medicine"},{"key":"10.1053\/gast.2001.21204_bib21","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1182\/blood.V69.2.454.454","article-title":"Epidemiological investigation of the prevalence of von Willebrand's disease","volume":"69","author":"Rodeghiero","year":"1987","journal-title":"Blood"},{"key":"10.1053\/gast.2001.21204_bib22","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S0002-9343(97)00239-8","article-title":"Acquired von Willebrand disease: concise review of occurrence, diagnosis, pathogenesis, and treatment","volume":"103","author":"Tefferi","year":"1997","journal-title":"Am J Med"},{"key":"10.1053\/gast.2001.21204_bib23","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/(SICI)1096-8652(199702)54:2<139::AID-AJH7>3.0.CO;2-Y","article-title":"Acquired von Willebrand's disease: a concise review","volume":"54","author":"Rinder","year":"1997","journal-title":"Am J Hematol"},{"key":"10.1053\/gast.2001.21204_bib24","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1097\/00000441-196711000-00002","article-title":"Telangiectasia: its relationship to the Minot\u2013von Willebrand syndrome","volume":"254","author":"Quick","year":"1967","journal-title":"Am J Med"},{"key":"10.1053\/gast.2001.21204_bib25","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0140-6736(76)90729-7","article-title":"Persistent gastrointestinal bleeding due to angiodysplasia of the gut in von Willebrand's disease","volume":"2","author":"Ramsay","year":"1976","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.21204_bib26","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0002-9343(77)90846-4","article-title":"von Willebrand's disease and hemorrhage telangiectasia. Association of two complex disorders of hemostasis resulting in life-threatening hemorrhage","volume":"62","author":"Ahr","year":"1977","journal-title":"Am J Med"},{"key":"10.1053\/gast.2001.21204_bib27","doi-asserted-by":"crossref","first-page":"921","DOI":"10.7326\/0003-4819-89-6-921","article-title":"Telangiectasia and von Willebrand disease in two families","volume":"89","author":"Conlon","year":"1978","journal-title":"Ann Intern Med"},{"key":"10.1053\/gast.2001.21204_bib28","first-page":"53","article-title":"Gastric radiotherapy as treatment of hereditary hemorrhagic telangiectasia","volume":"77","author":"Schwartz","year":"1982","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.21204_bib29","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/S0046-8177(84)80007-6","article-title":"Gastrointestinal angiodysplasia: a possible component of von Willebrand's disease","volume":"15","author":"Duray","year":"1987","journal-title":"Hum Pathol"},{"key":"10.1053\/gast.2001.21204_bib30","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1055\/s-0038-1661076","article-title":"A study of a caucasian family with variant von Willebrand's disease in association with vascular telangiectasia and haemoglobinopathy","volume":"51","author":"Hanna","year":"1984","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib31","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/ajh.2830410410","article-title":"Angiodysplasia and von Willebrand's disease type IIB treated with estrogen\/progester-one therapy","volume":"41","author":"Chey","year":"1992","journal-title":"Am J Hematol"},{"key":"10.1053\/gast.2001.21204_bib32","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/ajh.2830460325","article-title":"von Willebrand's disease, digestive angiodysplasia and estrogen-progesterone treatment","volume":"46","author":"Lavabre-Bertrand","year":"1994","journal-title":"Am J Hematol"},{"key":"10.1053\/gast.2001.21204_bib33","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0140-6736(76)90950-8","article-title":"Angiodysplasia in acquired von Willebrand disease","volume":"2","author":"Wautier","year":"1976","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.21204_bib34","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/0002-9343(78)90698-8","article-title":"Acquired von Willebrand's disease, platelet-release defect and angiodysplasia","volume":"65","author":"Rosborough","year":"1978","journal-title":"Am J Med"},{"key":"10.1053\/gast.2001.21204_bib35","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/0002-9343(79)90267-5","article-title":"Acquired von Willebrand disease associated with an inhibitor to factor VIII antigen and gastrointestinal telangiectasia","volume":"67","author":"Mc Grawth","year":"1979","journal-title":"Am J Med"},{"key":"10.1053\/gast.2001.21204_bib36","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/bjs.1800670910","article-title":"Gastrointestinal bleeding, angiodysplasia of the colon and acquired von Willebrand's disease","volume":"67","author":"Cass","year":"1980","journal-title":"Br J Surg"},{"key":"10.1053\/gast.2001.21204_bib37","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/ajh.2830270211","article-title":"Prolonged remission after life-threatening gastrointestinal hemorrhage from coexistent angiodysplasia and acquired bleeding diathesis","volume":"27","author":"Woodlock","year":"1988","journal-title":"Am J Hematol"},{"key":"10.1053\/gast.2001.21204_bib38","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1046\/j.1365-2141.1997.d01-1987.x","article-title":"Acquired von Willebrand disease in a patient with angiodysplasia resulting from immune-mediated clearance of von Willebrand factor","volume":"96","author":"Inbal","year":"1997","journal-title":"Br J Haematol"},{"key":"10.1053\/gast.2001.21204_bib39","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/(SICI)1096-8652(199902)60:2<151::AID-AJH13>3.0.CO;2-J","article-title":"Idiopathic immune-mediated acquired von Willebrand's disease in a patient with angiodysplasia: demonstration of an unusual inhibitor causing a functional defect and rapid clearance of von Willebrand factor","volume":"60","author":"Alhumood","year":"1999","journal-title":"Am J Hematol"},{"key":"10.1053\/gast.2001.21204_bib40","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/BF01536794","article-title":"Long-term results of treatment of vascular malformations of the gastrointestinal tract by neomydium YAG laser photocoagulation","volume":"35","author":"Naveau","year":"1990","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2001.21204_bib41","first-page":"287","article-title":"Vascular disorders","author":"Thomson","year":"1981"},{"key":"10.1053\/gast.2001.21204_bib42","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0735-1097(86)80460-0","article-title":"Determination of the stenotic aortic valve area in adults using Doppler echocardiography","volume":"7","author":"Otto","year":"1986","journal-title":"J Am Coll Cardiol"},{"key":"10.1053\/gast.2001.21204_bib43","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1055\/s-0037-1614468","article-title":"A new automated method for von Willebrand factor antigen measurement using latex particles","volume":"8","author":"Veyradier","year":"1999","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib44","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1182\/blood.V91.4.1325","article-title":"Screening for von Willebrand disease using a new analyzer using high shear stress: a study of 60 cases","volume":"91","author":"Fressinaud","year":"1998","journal-title":"Blood"},{"key":"10.1053\/gast.2001.21204_bib45","first-page":"590","article-title":"Multimeric structure of factor VIII\/von Willebrand factor in von Willebrand disease","volume":"95","author":"Meyer","year":"1980","journal-title":"J Lab Clin Med"},{"key":"10.1053\/gast.2001.21204_bib46","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1055\/s-0038-1651629","article-title":"Heparin binding assay of von Willebrand factor (vWF) in plasma milieu. Evidence of the importance of the multimerization degree of vWF","volume":"69","author":"De Romeuf","year":"1993","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib47","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0049-3848(98)00078-4","article-title":"von Willebrand factor: measuring its antigen or function? Correlation between the level of antigen, activity, and multimer size using various detection systems","volume":"91","author":"Fisher","year":"1998","journal-title":"Thromb Res"},{"key":"10.1053\/gast.2001.21204_bib48","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1172\/JCI113871","article-title":"Fibrinogen-independent platelet adhesion and thrombus formation on subendothelium mediated by glycoprotein IIb\/IIIa complex at high shear rate","volume":"83","author":"Weiss","year":"1989","journal-title":"J Clin Invest"},{"key":"10.1053\/gast.2001.21204_bib49","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1097\/00004836-199210000-00019","article-title":"The clinical and endoscopic spectrum of the watermelon stomach","volume":"15","author":"Gostout","year":"1992","journal-title":"J Clin Gastroenterol"},{"key":"10.1053\/gast.2001.21204_bib50","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1182\/blood.V67.3.758.758","article-title":"Loss of the largest von Willebrand factor multimers from the plasma of patients with congenital cardiac defects","volume":"67","author":"Gill","year":"1986","journal-title":"Blood"},{"key":"10.1053\/gast.2001.21204_bib51","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1055\/s-0038-1647035","article-title":"von Willebrand factor and mitral valve prolapse","volume":"60","author":"Froom","year":"1988","journal-title":"Thromb Haemost"},{"key":"10.1053\/gast.2001.21204_bib52","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/0140-6736(92)92155-9","article-title":"Heart valve stenosis and von Willebrand's factor multimers","volume":"340","author":"O'Brien","year":"1992","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.21204_bib53","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/S0140-6736(96)91240-4","article-title":"Reversal of aortic stenosis, bleeding gastrointestinal angiodysplasia, and von Willebrand syndrome by aortic valve replacement","volume":"347","author":"Anderson","year":"1996","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.21204_bib54","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/j.1365-2141.1992.tb03005.x","article-title":"Acquired von Willebrand's disease due to excessive fibrinolysis","volume":"81","author":"Eikenboom","year":"1992","journal-title":"Br J Haematol"},{"key":"10.1053\/gast.2001.21204_bib55","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1056\/NEJM195807242590416","article-title":"Gastrointestinal bleeding in aortic stenosis","volume":"259","author":"Heyde","year":"1958","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.21204_bib56","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0002-9610(86)90465-4","article-title":"Colonic vascular ectasias and aortic stenosis: coincidence or causal relationship?","volume":"151","author":"Greenstein","year":"1986","journal-title":"Am J Surg"},{"key":"10.1053\/gast.2001.21204_bib57","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/S0003-4975(10)62112-1","article-title":"The association of unexplained gastrointestinal bleeding with calcific aortic stenosis","volume":"44","author":"King","year":"1987","journal-title":"Ann Thorac Surg"},{"key":"10.1053\/gast.2001.21204_bib58","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1016\/S0016-5085(88)80095-7","article-title":"Aortic stenosis, idiopathic gastrointestinal bleeding and angiodysplasia: is there an association? A methodological critique of the literature","volume":"95","author":"Imperiale","year":"1988","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.21204_bib59","first-page":"75","article-title":"Prevalence of aortic valve stenosis in patients affected by gastrointestinal angiodysplasia","volume":"2","author":"Oneglia","year":"1993","journal-title":"Eur J Med"},{"key":"10.1053\/gast.2001.21204_bib60","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0016-5107(95)70038-2","article-title":"A prospective controlled evaluation of endoscopic detection of angiodysplasia and its association with aortic valve stenosis","volume":"42","author":"Bhutani","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/gast.2001.21204_bib61","doi-asserted-by":"crossref","first-page":"54","DOI":"10.7326\/0003-4819-105-1-54","article-title":"Cessation of recurrent bleeding from gastrointestinal angiodysplasia after aortic valve replacement","volume":"105","author":"Cappell","year":"1986","journal-title":"Ann Intern Med"},{"key":"10.1053\/gast.2001.21204_bib62","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0140-6736(92)92434-H","article-title":"Aortic stenosis and bleeding gastrointestinal angiodysplasia: is acquired von Willebrand's disease the link?","volume":"340","author":"Warkentin","year":"1992","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.21204_bib63","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1016\/S0140-6736(88)90762-3","article-title":"von Willebrand factor abnormalities in two patients with uraemia","volume":"2","author":"Rodeghiero","year":"1988","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.21204_bib64","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1002\/ajh.2830440409","article-title":"Multimeric pattern of plasma and platelet von Willebrand factor is normal in uremic patients","volume":"44","author":"Castaman","year":"1993","journal-title":"Am J Hematol"},{"key":"10.1053\/gast.2001.21204_bib65","first-page":"636","article-title":"Gastrointestinal bleeding caused by angiodysplasia: a difficult problem in patients with chronic renal failure receiving hemodialysis therapy","volume":"59","author":"Richardson","year":"1993","journal-title":"Am Surg"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508501751463?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508501751463?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T12:14:24Z","timestamp":1586348064000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508501751463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":65,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["S0016508501751463"],"URL":"https:\/\/doi.org\/10.1053\/gast.2001.21204","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2001,2]]}}}