{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:02:25Z","timestamp":1790881345988,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2001,5]]},"DOI":"10.1053\/gast.2001.24052","type":"journal-article","created":{"date-parts":[[2005,7,29]],"date-time":"2005-07-29T17:58:00Z","timestamp":1122659880000},"page":"1356-1362","source":"Crossref","is-referenced-by-count":361,"title":["Family history as a risk factor for colorectal cancer in inflammatory bowel disease"],"prefix":"10.1053","volume":"120","author":[{"given":"Johan","family":"Askling","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul W.","family":"Dickman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"Ekbom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Karl\u00e9n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olle","family":"Brostr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Lapidus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"L\u00f6fberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/gast.2001.24052_bib1","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/0016-5085(92)90029-X","article-title":"Survival and causes of death in patients with inflammatory bowel disease: a population-based study","volume":"103","author":"Ekbom","year":"1992","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib2","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1056\/NEJM197107012850103","article-title":"Cancer risk and life expectancy of children with ulcerative colitis","volume":"285","author":"Devroede","year":"1971","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.24052_bib3","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1056\/NEJM199412223312501","article-title":"A prospective study of family history and the risk of colorectal cancer","volume":"331","author":"Fuchs","year":"1994","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.24052_bib4","doi-asserted-by":"crossref","first-page":"785","DOI":"10.7326\/0003-4819-118-10-199305150-00005","article-title":"Cancer risk in relatives of patients with common colorectal cancer","volume":"118","author":"St John","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1053\/gast.2001.24052_bib5","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1002\/ijc.2910410407","article-title":"Family history of colorectal cancer as a risk factor for benign and malignant tumours of the large bowel. A case-control study","volume":"41","author":"Bonelli","year":"1988","journal-title":"Int J Cancer"},{"key":"10.1053\/gast.2001.24052_bib6","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/S0016-5085(98)70077-0","article-title":"Familial predisposition for colorectal cancer in chronic ulcerative colitis: a case-control study","volume":"115","author":"Nuako","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib7","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/S0016-5085(98)70580-3","article-title":"Family history as a risk factor for ulcerative colitis-associated colon cancer in cotton-top tamarin","volume":"114","author":"Bertone","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0016-5085(89)90058-9","article-title":"Effect of folate supplementation on the incidence of dysplasia and cancer in chronic ulcerative colitis. A case-control study","volume":"97","author":"Lashner","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1046\/j.1365-2036.2000.00698.x","article-title":"Colorectal cancer prevention in ulcerative colitis: a case-control study","volume":"14","author":"Eaden","year":"2000","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/gast.2001.24052_bib10","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1056\/NEJM199101103240203","article-title":"Familial occurrence of inflammatory bowel disease","volume":"324","author":"Orholm","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.24052_bib11","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1053\/gast.1996.v111.pm8780563","article-title":"Clinical characteristics of Crohn's disease in 72 families","volume":"111","author":"Colombel","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib12","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1053\/gast.1996.v111.pm8780559","article-title":"Crohn's disease: concordance for site and clinical type in affected family members\u2014potential hereditary influences","volume":"111","author":"Bayless","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0016-5085(97)70215-4","article-title":"The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis","volume":"112","author":"Lashner","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/ng1096-199","article-title":"Two stage genomewide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12","volume":"14","author":"Satsangi","year":"1996","journal-title":"Nat Genet"},{"key":"10.1053\/gast.2001.24052_bib15","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1097\/00000658-199706000-00009","article-title":"Crohn's disease and ulcerative colitis are associated with the DNA repair gene MLH1","volume":"225","author":"Pokorny","year":"1997","journal-title":"Ann Surg"},{"key":"10.1053\/gast.2001.24052_bib16","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0140-6736(96)91563-9","article-title":"Unifying hypothesis for inflammatory bowel disease and associated colon cancer: sticking the pieces together with sugar","volume":"347","author":"Rhodes","year":"1996","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.24052_bib17","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1136\/gut.29.2.206","article-title":"Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres","volume":"29","author":"Gyde","year":"1988","journal-title":"Gut"},{"key":"10.1053\/gast.2001.24052_bib18","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1111\/j.1572-0241.1999.01012.x","article-title":"Increased risk of cancer in ulcerative colitis: a population-based cohort study","volume":"94","author":"Karlen","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.24052_bib19","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1016\/0016-5085(94)90807-9","article-title":"Crohn's disease and cancer: a population-based cohort study","volume":"107","author":"Persson","year":"1994","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib20","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1056\/NEJM199011013231802","article-title":"Ulcerative colitis and colorectal cancer. A population-based study","volume":"323","author":"Ekbom","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.24052_bib21","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/0140-6736(90)91889-I","article-title":"Increased risk of large-bowel cancer in Crohn's disease with colonic involvement","volume":"336","author":"Ekbom","year":"1990","journal-title":"Lancet"},{"key":"10.1053\/gast.2001.24052_bib22","series-title":"The Swedish Hospital Discharge Register 1987-1996 Quality and Contents","year":"1998"},{"key":"10.1053\/gast.2001.24052_bib23","first-page":"105","article-title":"Definition and diagnosis of Crohn's disease","author":"Lennard-Jones","year":"1971"},{"key":"10.1053\/gast.2001.24052_bib24","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0016-5085(81)80021-2","article-title":"Incidence rates of ulcerative colitis and Crohn's disease in fifteen areas of the United States","volume":"81","author":"Garland","year":"1981","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.24052_bib25","first-page":"1","article-title":"The person-number systems of Sweden, Norway, Denmark, and Israel","volume":"2","author":"Lunde","year":"1980","journal-title":"Vital Health Stat 2"},{"key":"10.1053\/gast.2001.24052_bib26","doi-asserted-by":"crossref","first-page":"305","DOI":"10.3109\/02841868409136026","article-title":"Completeness of the Swedish Cancer Register. Non-notified cancer cases recorded on death certificates in 1978","volume":"23","author":"Mattsson","year":"1984","journal-title":"Acta Radiol Oncol"},{"key":"10.1053\/gast.2001.24052_bib27","first-page":"1","article-title":"Statistical methods in cancer research. Volume II. Series 82. The design and analysis of cohort studies","author":"Breslow","year":"1987","journal-title":"IARC Sci Publ"},{"key":"10.1053\/gast.2001.24052_bib28","first-page":"813","article-title":"Cancers of the large intestine","author":"Schottenfeld","year":"1996"},{"key":"10.1053\/gast.2001.24052_bib29","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1056\/NEJM199506083322312","article-title":"Family history and colorectal cancer","volume":"332","author":"Selby","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2001.24052_bib30","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1002\/ijc.2910470207","article-title":"Cancer incidence among parents of patients with colorectal cancer","volume":"47","author":"Sondergaard","year":"1991","journal-title":"Int J Cancer"},{"key":"10.1053\/gast.2001.24052_bib31","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1007\/BF02053699","article-title":"The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)","volume":"34","author":"Vasen","year":"1991","journal-title":"Dis Colon Rectum"},{"key":"10.1053\/gast.2001.24052_bib32","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1136\/gut.42.5.711","article-title":"Is colonoscopic surveillance reducing colorectal cancer mortality in ulcerative colitis? A population based case control study","volume":"42","author":"Karlen","year":"1998","journal-title":"Gut"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508501665193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508501665193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T12:14:45Z","timestamp":1586348085000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508501665193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["S0016508501665193"],"URL":"https:\/\/doi.org\/10.1053\/gast.2001.24052","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}