{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T08:14:17Z","timestamp":1790151257780,"version":"4.0.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1053\/gast.2001.28656","type":"journal-article","created":{"date-parts":[[2005,7,29]],"date-time":"2005-07-29T17:58:00Z","timestamp":1122659880000},"page":"1054-1063","source":"Crossref","is-referenced-by-count":152,"title":["Impaired drinking capacity in patients with functional dyspepsia: Relationship with proximal stomach function"],"prefix":"10.1053","volume":"121","author":[{"given":"Guy E.","family":"Boeckxstaens","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bram D.J.","family":"Van Den Elzen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siem H.","family":"Heisterkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido N.J.","family":"Tytgat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/gast.2001.28656_bib1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1136\/gut.44.1.55","article-title":"Gastric accommodation in non-ulcer dyspepsia and the roles of Helicobacter pylori infection and vagal function","volume":"44","author":"Thumshirn","year":"1999","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib2","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1136\/gut.42.6.823","article-title":"Responses to gastric distension in functional dyspepsia","volume":"42","author":"Salet","year":"1998","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib3","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1016\/S0016-5085(98)70012-5","article-title":"Role of impaired gastric accommodation to a meal in functional dyspepsia","volume":"115","author":"Tack","year":"1998","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.28656_bib4","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/BF02213124","article-title":"Impaired accommodation of proximal stomach to a meal in functional dyspepsia","volume":"41","author":"Gilja","year":"1996","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2001.28656_bib5","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/gut.35.3.327","article-title":"Abnormal intragastric distribution of food during gastric emptying in functional dyspepsia patients","volume":"35","author":"Troncon","year":"1994","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib6","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1136\/gut.42.6.814","article-title":"Symptoms and visceral perception in severe functional and organic dyspepsia","volume":"42","author":"Mertz","year":"1998","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib7","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1023\/A:1018891409189","article-title":"Gastric hypersensitivity in nonulcer dyspepsia: an inconsistent finding","volume":"42","author":"Klatt","year":"1997","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2001.28656_bib8","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/0016-5085(91)90726-2","article-title":"The origin of symptoms on the brain-gut axis in functional dyspepsia","volume":"101","author":"Mearin","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.28656_bib9","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1007\/BF01307517","article-title":"Abnormal perception of visceral pain in response to gastric distension in chronic idiopathic dyspepsia. The irritable stomach syndrome","volume":"36","author":"Lemann","year":"1991","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2001.28656_bib10","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1046\/j.1365-2982.2000.00184.x","article-title":"Influence of a 5HT1 receptor agonist on gastric accommodation and initial transpyloric flow in healthy subjects","volume":"12","author":"Vingerhagen","year":"2000","journal-title":"Neurogastroenterol Motil"},{"key":"10.1053\/gast.2001.28656_bib11","doi-asserted-by":"crossref","first-page":"2757","DOI":"10.1023\/A:1026628000491","article-title":"Proximal and distal gastric distension in normal subjects and H. pylori-positive and -negative dyspeptic patients and correlation with symptoms","volume":"43","author":"Marzio","year":"1998","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2001.28656_bib12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1365-2982.1998.00080.x","article-title":"Visceral perceptions and gastric myoelectrical activity in healthy women and in patients with bulimia nervosa","volume":"10","author":"Koch","year":"1998","journal-title":"Neurogastroenterol Motil"},{"issue":"suppl 2","key":"10.1053\/gast.2001.28656_bib13","doi-asserted-by":"crossref","first-page":"II37","DOI":"10.1136\/gut.45.2008.ii37","article-title":"Functional gastroduodenal disorders","volume":"45","author":"Talley","year":"1999","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib14","doi-asserted-by":"crossref","first-page":"2390","DOI":"10.1111\/j.1572-0241.1999.01363.x","article-title":"Validity of a new quality of life scale for functional dyspepsia: a United States multicenter trial of the Nepean Dyspepsia Index","volume":"94","author":"Talley","year":"1999","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.28656_bib15","doi-asserted-by":"crossref","first-page":"A389","DOI":"10.1016\/S0016-5085(00)83667-7","article-title":"A satiety test to assess gastric accommodation in functional dyspepsia (abstr)","volume":"118","author":"Tack","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.28656_bib16","doi-asserted-by":"crossref","first-page":"A618","DOI":"10.1016\/S0016-5085(00)84612-0","article-title":"Lack of effect of fundic relaxation on the drinking capacity and symptoms after a drink test in healthy volunteers and functional dyspeptics (abstr)","volume":"118","author":"Boeckxstaens","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.28656_bib17","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1016\/0016-5085(90)90333-V","article-title":"Perception and reflex relaxation of the stomach in response to gut distention","volume":"98","author":"Azpiroz","year":"1990","journal-title":"Gastroenterology"},{"issue":"suppl 2","key":"10.1053\/gast.2001.28656_bib18","first-page":"A670","article-title":"The distal stomach is responsible for symptomatic gastric accommodation in functional dyspeptics (abstr)","volume":"118","author":"Caldarella","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2001.28656_bib19","first-page":"G418","article-title":"Differential symptomatic and electrogastrographic effects of distal and proximal human gastric distension","volume":"275","author":"Ladabaum","year":"1998","journal-title":"Am J Physiol"},{"key":"10.1053\/gast.2001.28656_bib20","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/ajcn\/66.1.127","article-title":"Relation between postprandial satiation and antral area in normal subjects","volume":"66","author":"Jones","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/gast.2001.28656_bib21","first-page":"485","article-title":"Impaired small intestinal peristaltic reflexes and sensory thresholds are independent functional disturbances in patients with chronic unexplained dyspepsia","volume":"91","author":"Holtmann","year":"1996","journal-title":"Am J Gastroenterol"},{"key":"10.1053\/gast.2001.28656_bib22","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1136\/gut.42.4.501","article-title":"Altered vagal and intestinal mechanosensory function in chronic unexplained dyspepsia","volume":"42","author":"Holtmann","year":"1998","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib23","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1111\/j.1469-7793.1998.579bw.x","article-title":"Modulation of gut perception in humans by spatial summation phenomena","volume":"506","author":"Serra","year":"1998","journal-title":"J Physiol"},{"key":"10.1053\/gast.2001.28656_bib24","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1046\/j.1365-2036.1996.109280000.x","article-title":"Effect of the kappa agonist fedotozine on perception of gastric distension in healthy humans","volume":"10","author":"Coffin","year":"1996","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1053\/gast.2001.28656_bib25","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1136\/gut.41.5.664","article-title":"Efficacy and safety of the peripheral kappa agonist fedotozine versus placebo in the treatment of functional dyspepsia","volume":"41","author":"Read","year":"1997","journal-title":"Gut"},{"key":"10.1053\/gast.2001.28656_bib26","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1007\/BF02087560","article-title":"Double-blind dose-re-sponse multicenter comparison of fedotozine and placebo in treatment of nonulcer dyspepsia","volume":"39","author":"Fraitag","year":"1994","journal-title":"Dig Dis Sci"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508501489979?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508501489979?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,9]],"date-time":"2019-03-09T16:13:46Z","timestamp":1552148026000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508501489979"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0016508501489979"],"URL":"https:\/\/doi.org\/10.1053\/gast.2001.28656","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}