{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:21:18Z","timestamp":1790130078778,"version":"4.0.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2002,6,1]],"date-time":"2002-06-01T00:00:00Z","timestamp":1022889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2002,6]]},"DOI":"10.1053\/gast.2002.33600","type":"journal-article","created":{"date-parts":[[2005,7,29]],"date-time":"2005-07-29T17:58:00Z","timestamp":1122659880000},"page":"1793-1799","source":"Crossref","is-referenced-by-count":97,"title":["Lactose malabsorption and intolerance and peak bone mass"],"prefix":"10.1053","volume":"122","author":[{"given":"Michele","family":"Di Stefano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graziamaria","family":"Veneto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Malservisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Cecchetti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Licia","family":"Minguzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Strocchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gino Roberto","family":"Corazza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/gast.2002.33600_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4757-0620-8_1","article-title":"Genetics of lactose digestion in humans","volume":"16","author":"Flatz","year":"1987","journal-title":"Adv Hum Genet"},{"key":"10.1053\/gast.2002.33600_bib2","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1056\/NEJM197505292922205","article-title":"Lactose and milk intolerance: clinical implications","volume":"292","author":"Bayless","year":"1975","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.33600_bib3","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1079\/BJN19950050","article-title":"Lactose intolerance and bone mass in postmenopausal Italian women","volume":"73","author":"Corazza","year":"1995","journal-title":"Br J Nutr"},{"key":"10.1053\/gast.2002.33600_bib4","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0002-8223(99)00195-9","article-title":"Predictors of milk consumption in a population of 17- to 35 year-old military personnel","volume":"99","author":"Klesges","year":"1999","journal-title":"J Am Diet Assoc"},{"key":"10.1053\/gast.2002.33600_bib5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S8756-3282(97)00172-5","article-title":"Lactose intolerance associated with fractures of weight-bearing bones in Finnish women aged 38-57 years","volume":"21","author":"Honkanen","year":"1997","journal-title":"Bone"},{"key":"10.1053\/gast.2002.33600_bib6","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/00005176-199405000-00006","article-title":"Bone mineral content and dietary calcium intake in children prescribed a low-lactose diet","volume":"18","author":"Stallings","year":"1994","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1053\/gast.2002.33600_bib7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1097\/00005176-200003000-00018","article-title":"Risk of inadequate bone mineralization in diseases involving long-term suppression of dairy products","volume":"30","author":"Infante","year":"2000","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1053\/gast.2002.33600_bib8","series-title":"Osteoporosis. Etiology, diagnosis and management","author":"Riggs","year":"1988"},{"key":"10.1053\/gast.2002.33600_bib9","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/BF01880413","article-title":"The contribution of bone loss to postmenopausal osteoporosis","volume":"1","author":"Hui","year":"1990","journal-title":"Osteoporos Int"},{"key":"10.1053\/gast.2002.33600_bib10","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1056\/NEJM199011013231809","article-title":"Postmenopausal bone loss\u2014a risk factor for osteoporosis","volume":"323","author":"Johnston","year":"1990","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.33600_bib11","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1001\/jama.1994.03520240070044","article-title":"Optimal calcium intake","volume":"272","author":"Consensus Conference Panel","year":"1994","journal-title":"JAMA"},{"key":"10.1053\/gast.2002.33600_bib12","first-page":"617","article-title":"Osteoporosis and bone metabolic parameters in dependence upon calcium intake through milk and milk products","volume":"47","author":"Stracke","year":"1992","journal-title":"Eur J Clin Nutr"},{"key":"10.1053\/gast.2002.33600_bib13","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/ajcn\/54.2.425","article-title":"Influences of calcium intake and growth indexes on vertebral bone mineral density in young females","volume":"54","author":"Sentipal","year":"1991","journal-title":"Am J Clin Nutr"},{"issue":"suppl","key":"10.1053\/gast.2002.33600_bib14","doi-asserted-by":"crossref","first-page":"1426S","DOI":"10.1093\/jn\/124.suppl_8.1426S","article-title":"Consumption of calcium in the US: food sources and intake levels","volume":"124","author":"Fleming","year":"1994","journal-title":"J Nutr"},{"key":"10.1053\/gast.2002.33600_bib15","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/0002-8223(94)90366-2","article-title":"Associations of social and demographic variables with calcium intakes of high school students","volume":"94","author":"Barr","year":"1994","journal-title":"J Am Diet Assoc"},{"key":"10.1053\/gast.2002.33600_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM199507063330101","article-title":"A comparison of symptoms after the consumption of milk or lactose-hydrolyzed milk by people with self-reported severe lactose intolerance","volume":"333","author":"Suarez","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.33600_bib17","first-page":"116","article-title":"Weight-height indices","volume":"28","author":"Goldbourt","year":"1974","journal-title":"Br J Prev Soc Med"},{"key":"10.1053\/gast.2002.33600_bib18","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0016-5085(87)90313-1","article-title":"Fasting breath hydrogen in celiac disease","volume":"93","author":"Corazza","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.33600_bib19","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/0016-5085(86)90686-4","article-title":"Influence of the oropharyngeal microflora on the measurements of exhaled breath hydrogen","volume":"91","author":"Thompson","year":"1986","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.33600_bib20","doi-asserted-by":"crossref","first-page":"1980","DOI":"10.1093\/clinchem\/29.11.1980","article-title":"Time-course of cigarette smoke contamination of clinical hydrogen breath-analysis tests","volume":"29","author":"Rosenthal","year":"1983","journal-title":"Clin Chem"},{"key":"10.1053\/gast.2002.33600_bib21","first-page":"147","article-title":"Breath hydrogen (H2) response to carbohydrate malabsorption after exercise","volume":"102","author":"Payne","year":"1983","journal-title":"J Lab Clin Med"},{"key":"10.1053\/gast.2002.33600_bib22","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0016-5085(91)90475-Z","article-title":"Reproducibility of measurements of trace gas concentrations in expired air","volume":"101","author":"Strocchi","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.33600_bib23","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1007\/BF01297077","article-title":"Prevalence and consistency of low breath H2 excretion following lactulose ingestion. Possible implications for the clinical use of the H2 breath test","volume":"38","author":"Corazza","year":"1993","journal-title":"Dig Dis Sci"},{"key":"10.1053\/gast.2002.33600_bib24","first-page":"695","article-title":"The possible role of breath methane measurement in detecting carbohydrate malabsorption","volume":"124","author":"Corazza","year":"1994","journal-title":"J Lab Clin Med"},{"key":"10.1053\/gast.2002.33600_bib25","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/0016-5085(93)90145-3","article-title":"Detection of malabsorption of low doses of carbohydrate: accuracy of various breath H2 criteria","volume":"105","author":"Strocchi","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.33600_bib26","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1093\/ajcn\/50.5.1121","article-title":"Development of a diet history questionnaire for studies of old persons","volume":"50","author":"Hankin","year":"1989","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/gast.2002.33600_bib27","series-title":"Tabelle di composizione degli alimenti","author":"Istituto Italiano della Nutrizione","year":"1983"},{"key":"10.1053\/gast.2002.33600_bib28","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650090802","article-title":"The diagnosis of osteoporosis","volume":"9","author":"Kanis","year":"1994","journal-title":"J Bone Miner Res"},{"key":"10.1053\/gast.2002.33600_bib29","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1359\/jbmr.1999.14.10.1708","article-title":"Femoral neck is a sensitive indicator of bone loss in immobilized hind limb of mouse","volume":"14","author":"Jamsa","year":"1999","journal-title":"J Bone Miner Res"},{"key":"10.1053\/gast.2002.33600_bib30","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S8756-3282(98)00078-7","article-title":"Decreased bone mass and bone elasticity in mice lacking the transforming growth factor-\u03b21 gene","volume":"23","author":"Geiser","year":"1998","journal-title":"Bone"},{"key":"10.1053\/gast.2002.33600_bib31","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1002\/jbmr.5650071110","article-title":"Diurnal variation in serum markers of type I collagen synthesis and degradation in healthy premenopausal women","volume":"7","author":"Hassager","year":"1992","journal-title":"J Bone Miner Res"},{"key":"10.1053\/gast.2002.33600_bib32","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1093\/clinchem\/33.8.1364","article-title":"Highly sensitive two-site immunoradiometric assay of parathyrin, and its clinical utility in evaluating patients with hypercalcemia","volume":"33","author":"Nussbaum","year":"1987","journal-title":"Clin Chem"},{"key":"10.1053\/gast.2002.33600_bib33","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1651-2227.1990.tb11327.x","article-title":"High total and free 1,25-dihydroxyvitamin D concentrations in serum of premature infants","volume":"79","author":"Schilling","year":"1990","journal-title":"Acta Paediatr Scand"},{"key":"10.1053\/gast.2002.33600_bib34","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1093\/clinchem\/36.7.1328","article-title":"Radioimmunoassay of the carboxyterminal propeptide of human type I procollagen","volume":"36","author":"Mellko","year":"1990","journal-title":"Clin Chem"},{"key":"10.1053\/gast.2002.33600_bib35","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/clinchem\/39.4.635","article-title":"Radioimmunoassay for the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen: a new serum marker of bone collagen degradation","volume":"39","author":"Risteli","year":"1993","journal-title":"Clin Chem"},{"key":"10.1053\/gast.2002.33600_bib36","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/8756-3282(96)00107-X","article-title":"Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women","volume":"19","author":"Honkanen","year":"1996","journal-title":"Bone"},{"key":"10.1053\/gast.2002.33600_bib37","first-page":"37","article-title":"Report on the activities of the subnetwork on trace elements status in food","author":"Kumpalainen","year":"1989"},{"issue":"suppl 2","key":"10.1053\/gast.2002.33600_bib38","first-page":"1","article-title":"Clinical indications for bone mass measurement","volume":"4","author":"Johnston","year":"1989","journal-title":"J Bone Miner Res"},{"key":"10.1053\/gast.2002.33600_bib39","doi-asserted-by":"crossref","first-page":"516","DOI":"10.7326\/0003-4819-112-7-516","article-title":"Screening for osteoporosis","volume":"112","author":"Melton","year":"1990","journal-title":"Ann Intern Med"},{"key":"10.1053\/gast.2002.33600_bib40","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1097\/00005176-199405000-00006","article-title":"Bone mineral content and dietary calcium intake in children prescribed a low-lactose diet","volume":"18","author":"Stallings","year":"1994","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"10.1053\/gast.2002.33600_bib41","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0026-0495(77)90052-X","article-title":"Comparative skeletal mass and radial bone mineral content in black and white women","volume":"26","author":"Cohn","year":"1977","journal-title":"Metabolism"},{"key":"10.1053\/gast.2002.33600_bib42","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1001\/jama.1989.03420070075034","article-title":"Senile osteoporosis reconsidered","volume":"261","author":"Resnick","year":"1989","journal-title":"JAMA"},{"key":"10.1053\/gast.2002.33600_bib43","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1056\/NEJM199511303332209","article-title":"The treatment of postmenopausal osteoporosis","volume":"333","author":"Sambrook","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.33600_bib44","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0749-3797(18)30875-4","article-title":"Comparative uptake of calcium from milk and a calcium-rich mineral water in lactose intolerant adults: implications for treatment of osteoporosis","volume":"7","author":"Halpern","year":"1991","journal-title":"Am J Prev Med"},{"key":"10.1053\/gast.2002.33600_bib45","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1093\/ajcn\/68.5.1118","article-title":"Lactose maldigestion is not an impediment to the intake of 1500 mg calcium daily as dairy products","volume":"68","author":"Suarez","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"10.1053\/gast.2002.33600_bib46","first-page":"1","article-title":"Optimal calcium intake","volume":"12","author":"National Institute of Health","year":"1994","journal-title":"NIH Consensus Statement"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508502000136?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508502000136?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T12:16:39Z","timestamp":1586348199000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508502000136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,6]]},"references-count":46,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2002,6]]}},"alternative-id":["S0016508502000136"],"URL":"https:\/\/doi.org\/10.1053\/gast.2002.33600","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2002,6]]}}}