{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T10:18:38Z","timestamp":1784801918085,"version":"3.55.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2002,9,1]],"date-time":"2002-09-01T00:00:00Z","timestamp":1030838400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology"],"published-print":{"date-parts":[[2002,9]]},"DOI":"10.1053\/gast.2002.35351","type":"journal-article","created":{"date-parts":[[2002,8,27]],"date-time":"2002-08-27T19:56:12Z","timestamp":1030478172000},"page":"728-734","source":"Crossref","is-referenced-by-count":141,"title":["Banding ligation versus nadolol and isosorbide mononitrate for the prevention of esophageal variceal rebleeding"],"prefix":"10.1053","volume":"123","author":[{"given":"Gin-Ho","family":"Lo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Hsiu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping-I","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiun-Ku","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Lun","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwok-Hung","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/gast.2002.35351_bib1","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1056\/NEJM198905253202107","article-title":"Controversies in the management of bleeding esophageal varices","volume":"320","author":"Terblanche","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.35351_bib2","first-page":"1","article-title":"Gastrointestinal hemorrhage and portal hypertension","author":"Lake","year":"2000"},{"key":"10.1053\/gast.2002.35351_bib3","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/hep.1840050410","article-title":"A prospective, randomized trial of chronic esophageal variceal sclerotherapy","volume":"5","author":"Korula","year":"1985","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib4","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/0016-5085(89)91627-2","article-title":"Role of endoscopic variceal sclerotherapy in the long-term management of variceal bleeding: a meta-analysis","volume":"96","author":"Infante-Rivard","year":"1989","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.35351_bib5","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1056\/NEJM198112033052302","article-title":"Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a controlled study","volume":"305","author":"Lebrec","year":"1981","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.35351_bib6","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/0016-5085(93)90158-9","article-title":"Propranolol versus sclerotherapy in preventing variceal rebleeding: a randomized controlled trial","volume":"105","author":"Teres","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.35351_bib7","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1056\/NEJM199206043262304","article-title":"Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices","volume":"326","author":"Stiegmann","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.35351_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/0003-4819-119-1-199307010-00001","article-title":"Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices","volume":"119","author":"Laine","year":"1993","journal-title":"Ann Intern Med"},{"key":"10.1053\/gast.2002.35351_bib9","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/hep.1840220215","article-title":"A prospective, randomized trial of sclerotherapy versus ligation in the management of bleeding esophageal varices","volume":"22","author":"Lo","year":"1995","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib10","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1002\/hep.510250509","article-title":"Emergency banding ligation versus sclerotherapy for the control of active bleeding from esophageal varices","volume":"25","author":"Lo","year":"1997","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib11","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/hep.1840110212","article-title":"Enhancement of portal pressure reduction by the association of isosorbide-5-mononitrate to propranolol administration in patients with cirrhosis","volume":"11","author":"Garcia-Pagan","year":"1990","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib12","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/hep.1840180302","article-title":"Propranolol compared with propranolol plus isosorbide dinitrate in portal-hypertensive patients: long-term hemodynamic and renal effects","volume":"18","author":"Vorobioff","year":"1993","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib13","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1002\/hep.1840200620","article-title":"Propranolol plus isosorbide-5-mononitrate for portal hypertension in cirrhosis: long-term hemodynamic and renal effects","volume":"20","author":"Morillas","year":"1994","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib14","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1053\/jhep.2000.8106","article-title":"Isosorbide mononitrate and propranolol compared with propranolol alone for the prevention of variceal rebleeding","volume":"31","author":"Gournay","year":"2000","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib15","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1056\/NEJM199606203342502","article-title":"Nadolol plus isosorbide mononitrate compared with sclerotherapy for the prevention of variceal rebleeding","volume":"334","author":"Villanueva","year":"1996","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.35351_bib16","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1053\/gast.2001.22580","article-title":"Current management of the complications of cirrhosis and portal hypertension: variceal hemorrhage, ascites, and spontaneous bacterial peritonitis","volume":"120","author":"Garcia-Tsao","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1053\/gast.2002.35351_bib17","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1056\/NEJMoa003223","article-title":"Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal rebleeding","volume":"345","author":"Villanueva","year":"2001","journal-title":"N Engl J Med"},{"key":"10.1053\/gast.2002.35351_bib18","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/bjs.1800600817","article-title":"Transection of esophagus for bleeding esophageal varices","volume":"60","author":"Pugh","year":"1973","journal-title":"Br J Surg"},{"key":"10.1053\/gast.2002.35351_bib19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0016-5107(81)73224-3","article-title":"Prediction of variceal hemorrhage by esophageal endoscopy","volume":"27","author":"Beppu","year":"1981","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/gast.2002.35351_bib20","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/0168-8278(92)90044-P","article-title":"Definitions, methodology and therapeutic strategies in portal hypertension","volume":"15","author":"De Franchis","year":"1992","journal-title":"J Hepatol"},{"key":"10.1053\/gast.2002.35351_bib21","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/S0168-8278(00)80320-7","article-title":"Updating consensus in portal hypertension: report of the Baveno III consensus workshop on definitions, methodology and therapeutic strategies in portal hypertension","volume":"33","author":"De Franchis","year":"2000","journal-title":"J Hepatol"},{"key":"10.1053\/gast.2002.35351_bib22","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/S0168-8278(97)80047-5","article-title":"Propranolol and sclerotherapy in the prevention of gastrointestinal rebleeding in patients with cirrhosis: a meta-analysis","volume":"26","author":"Bernard","year":"1997","journal-title":"J Hepatol"},{"key":"10.1053\/gast.2002.35351_bib23","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0016-5107(95)70070-6","article-title":"Changes in portal hypertensive gastropathy after endoscopic variceal sclerotherapy or ligation: an endoscopic observation","volume":"42","author":"Hou","year":"1995","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/gast.2002.35351_bib24","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1067\/mge.2001.114062","article-title":"The effects of endoscopic variceal ligation and propranolol on portal hypertensive gastropathy: a prospective, controlled trial","volume":"53","author":"Lo","year":"2001","journal-title":"Gastrointest Endosc"},{"key":"10.1053\/gast.2002.35351_bib25","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0168-8278(96)80189-9","article-title":"The impact of endoscopic variceal ligation on the pressure of the portal venous system","volume":"24","author":"Lo","year":"1996","journal-title":"J Hepatol"},{"key":"10.1053\/gast.2002.35351_bib26","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1053\/jhep.2001.23070","article-title":"Primary prevention of variceal bleeding. What's new?","volume":"32","author":"Lebrec","year":"2001","journal-title":"Hepatology"},{"key":"10.1053\/gast.2002.35351_bib27","first-page":"1923","article-title":"Nonsurgical treatment of variceal bleeding: new modalities","volume":"90","author":"Binmoeller","year":"1995","journal-title":"Am J Gastroenterol"},{"issue":"suppl 1","key":"10.1053\/gast.2002.35351_bib28","first-page":"81","article-title":"Isosorbide mononitrate with nadolol compared to nadolol alone for prevention of recurrent bleeding in cirrhosis. A double-blind placebo-controlled randomized trial (abstr)","volume":"30","author":"Patti","year":"1999","journal-title":"J Hepatol"}],"container-title":["Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508502001646?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0016508502001646?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T15:56:35Z","timestamp":1554911795000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0016508502001646"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9]]},"references-count":28,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2002,9]]}},"alternative-id":["S0016508502001646"],"URL":"https:\/\/doi.org\/10.1053\/gast.2002.35351","relation":{},"ISSN":["0016-5085"],"issn-type":[{"value":"0016-5085","type":"print"}],"subject":[],"published":{"date-parts":[[2002,9]]}}}