{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:21:37Z","timestamp":1777908097178,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2001,10]]},"DOI":"10.1053\/hupa.2001.28226","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T03:46:10Z","timestamp":1030247170000},"page":"1116-1124","source":"Crossref","is-referenced-by-count":122,"title":["Extraskeletal myxoid chondrosarcoma: A clinicopathologic, immunohistochemical, and molecular analysis of 18 cases"],"prefix":"10.1053","volume":"32","author":[{"given":"Sumika","family":"Okamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Hisaoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuyoshi","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Imamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Kanda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyohei","family":"Shimajiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/hupa.2001.28226_bib1","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0046-8177(72)80042-X","article-title":"Extraskeletal myxoid chondrosarcoma: An analysis of 34 cases","volume":"3","author":"Enzinger","year":"1972","journal-title":"Hum Pathol"},{"key":"10.1053\/hupa.2001.28226_bib2","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1002\/1097-0142(19921215)70:12<2827::AID-CNCR2820701217>3.0.CO;2-V","article-title":"Extraskeletal myxoid chondrosarcoma: A clinicopathologic study of ten patients with long-term follow-up","volume":"70","author":"Saleh","year":"1992","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28226_bib3","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/0046-8177(95)90196-5","article-title":"Myxoid chondrosarcoma of soft tissue and bone: A retrospective study of 11 cases","volume":"26","author":"Abramovici","year":"1995","journal-title":"Hum Pathol"},{"key":"10.1053\/hupa.2001.28226_bib4","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1097\/00000478-199906000-00002","article-title":"Extraskeletal myxoid chondrosarcoma: A reappraisal of its morphologic spectrum and prognostic factors based on 117 cases","volume":"23","author":"Meis-Kindblom","year":"1999","journal-title":"Am J Surg Pathol"},{"key":"10.1053\/hupa.2001.28226_bib5","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/modpathol.3880161","article-title":"Extraskeletal myxoid chondrosarcoma: A clinicopathologic, immunohistochemical, and ploidy analysis of 23 cases","volume":"13","author":"Oliveira","year":"2000","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28226_bib6","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1002\/(SICI)1097-0142(19981015)83:8<1504::AID-CNCR5>3.0.CO;2-B","article-title":"Skeletal and extraskeletal myxoid chondrosarcoma: A comparative clinicopathologic, ultrastructural, and molecular study","volume":"83","author":"Antonescu","year":"1998","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28226_bib7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1046\/j.1365-2559.1999.00735.x","article-title":"High-grade extraskeletal myxoid chondrosarcoma: A high-grade epithelioid malignancy","volume":"35","author":"Lucas","year":"1999","journal-title":"Histopathology"},{"key":"10.1053\/hupa.2001.28226_bib8","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/1097-0142(197601)37:1<300::AID-CNCR2820370140>3.0.CO;2-#","article-title":"Ultrastructure of the so-called \u201cchordoid sarcoma\u201d: Evidence supporting cartilaginous differentiation","volume":"37","author":"Weiss","year":"1976","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28226_bib9","first-page":"439","article-title":"Extraskeletal myxoid chondrosarcoma: A clinicophathologic and electron microscopic study","volume":"31","author":"Tsuneyoshi","year":"1981","journal-title":"Acta Pathol Jpn"},{"key":"10.1053\/hupa.2001.28226_bib10","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1007\/BF00431241","article-title":"Ultrastructural Study of conventional chondosarcomas and myxoid-and mesenchymal-chondrosarcomas","volume":"396","author":"Martinez-Tello","year":"1982","journal-title":"Virchows Archiv [A]"},{"key":"10.1053\/hupa.2001.28226_bib11","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1002\/1097-0142(19831115)52:10<1886::AID-CNCR2820521020>3.0.CO;2-F","article-title":"Myxoid chondrosarcoma of the synovial tissue: A clinicopathologic, histochemical, and ultrastructural analysis","volume":"52","author":"Kindblom","year":"1983","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28226_bib12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/BF00666219","article-title":"Chordoid sarcoma (extraskeletal myxoid chondrosarcoma): A light and electron microscope study","volume":"399","author":"Dardic","year":"1983","journal-title":"Virchows Arch [A]"},{"key":"10.1053\/hupa.2001.28226_bib13","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1111\/j.1365-2559.1986.tb02500.x","article-title":"Extraskeletal myxoid chondrosarcoma: A histochemical and immunohistochemical study","volume":"10","author":"Fletcher","year":"1986","journal-title":"Histopathology"},{"key":"10.1053\/hupa.2001.28226_bib14","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0165-4608(85)90187-6","article-title":"Myxoid chondrosarcoma with a translocation involving chromosomes 9 and 22","volume":"14","author":"Hinrichs","year":"1985","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1053\/hupa.2001.28226_bib15","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0046-8177(86)80036-3","article-title":"Microtubular aggregates within rough endoplasmic reticulum: An unusual ultrastructural feature of extraskeletal myxoid chondrosarcoma","volume":"17","author":"Deblois","year":"1986","journal-title":"Hum Pathol"},{"key":"10.1053\/hupa.2001.28226_bib16","first-page":"77","article-title":"Skeletal myxoid chondrosarcoma with microtubular aggregates within rough endoplasmic reticulum","volume":"112","author":"Wolford","year":"1988","journal-title":"Arch Pathol Lab Med"},{"key":"10.1053\/hupa.2001.28226_bib17","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/path.1711560111","article-title":"Extraskeletal myxoid chondrosarcoma characterized by microtubular aggregates in the rough endoplasmic reticulum and tubulin immunoreactivity","volume":"156","author":"Suzuki","year":"1988","journal-title":"J Pathol"},{"key":"10.1053\/hupa.2001.28226_bib18","first-page":"383","article-title":"Two cases of extraskeletal myxoid chondrosarcoma with special reference to microtubular aggregates","volume":"23","author":"Iwata","year":"1990","journal-title":"J Clin Electron Microsc"},{"key":"10.1053\/hupa.2001.28226_bib19","first-page":"8A","article-title":"Neuroendocrine differentiation in adult soft tissue sarcoma with features of extraskeletal myxoid chondrosarcoma: Report of seven cases","volume":"11","author":"Chhieng","year":"1998","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28226_bib20","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1097\/00000478-200007000-00015","article-title":"Extraskeletal myxoid chondrosarcoma with neuroendocrine differentiation: A pathologic, cytogenetic, and molecular study of a case with a novel translocation t(9;17)(q22;q11.2)","volume":"24","author":"Harris","year":"2000","journal-title":"Am J Surg Pathol"},{"key":"10.1053\/hupa.2001.28226_bib21","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1034\/j.1600-0560.2000.027003141.x","article-title":"Expression of the intermediate filament peripherin in extraskeletal myxoid chondrosarcoma","volume":"27","author":"Cummings","year":"2000","journal-title":"Cutan Pathol"},{"key":"10.1053\/hupa.2001.28226_bib22","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0165-4608(88)90103-3","article-title":"Recurrent breakpoints at 9q31 and 22q12.2 in extraskeletal myxoid chondrosarcoma","volume":"30","author":"Turc-Carel","year":"1988","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1053\/hupa.2001.28226_bib23","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0165-4608(91)90561-8","article-title":"Rearrangement of 9q22: A crucial event in extraskeletal myxoid chondrosarcoma?","volume":"52","author":"Mark-Bendel","year":"1991","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1053\/hupa.2001.28226_bib24","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/ijc.2910620407","article-title":"Translocation t(9;22)(q22;q12) is a primary cytogenetic abnormality in extraskeletal myxoid chondrosarcoma","volume":"62","author":"Stenman","year":"1995","journal-title":"Int J Cancer"},{"key":"10.1053\/hupa.2001.28226_bib25","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0165-4608(94)00201-0","article-title":"Translocation (9;22)(q22;q12): A recurrent chromosome abnormality in extraskeletal myxoid chondrosarcoma","volume":"81","author":"Hirabayashi","year":"1995","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1053\/hupa.2001.28226_bib26","first-page":"765","article-title":"t(9;22)(q22-31;q11-12) is a consistent marker of extraskeletal myxoid chondrosarcoma: Evaluation of three cases","volume":"8","author":"Sciot","year":"1995","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28226_bib27","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1093\/hmg\/4.12.2219","article-title":"Oncogenic conversion of a novel orphan nuclear receptor by chromosome translocation","volume":"4","author":"Labelle","year":"1995","journal-title":"Hum Mol Genet"},{"key":"10.1053\/hupa.2001.28226_bib28","first-page":"229","article-title":"Fusion of the EWS gene to CHN, a member of the steroid\/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma","volume":"12","author":"Clark","year":"1996","journal-title":"Oncogene"},{"key":"10.1053\/hupa.2001.28226_bib29","first-page":"1049","article-title":"Molecular analysis of the fusion of EWS to an orphan nuclear receptor gene in extraskeletal myxoid chondrosarcoma","volume":"150","author":"Brody","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1053\/hupa.2001.28226_bib30","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1038\/sj.onc.1202675","article-title":"The EWS\/TEC fusion protein encoded by the t(9;22) chromosomal translocation in human chondrosarcomas is a highly potent transcriptional activator","volume":"18","author":"Labelle","year":"1999","journal-title":"Oncogene"},{"key":"10.1053\/hupa.2001.28226_bib31","first-page":"5064","article-title":"Fusion of the EWS-related gene TAF2N to TEC in extraskeletal myxoid chondrosarcoma","volume":"59","author":"Sj\u00f6gren","year":"1999","journal-title":"Cancer Res"},{"key":"10.1053\/hupa.2001.28226_bib32","doi-asserted-by":"crossref","first-page":"7594","DOI":"10.1038\/sj.onc.1203155","article-title":"Fusion of the RBP56 and CHN genes in extraskeletal myxoid chondrosarcomas with translocation t(9;17)(q22;q11)","volume":"18","author":"Panagopoulos","year":"1999","journal-title":"Oncogene"},{"key":"10.1053\/hupa.2001.28226_bib33","doi-asserted-by":"crossref","first-page":"7599","DOI":"10.1038\/sj.onc.1203156","article-title":"Identification of a novel fusion gene involving hTAFII68 and CHN from a t(9;17)(q22;q11.2) translocation in an extraskeletal myxoid chondrosarcoma","volume":"18","author":"Attwooll","year":"1999","journal-title":"Oncogene"},{"key":"10.1053\/hupa.2001.28226_bib34","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1111\/j.1365-2559.1985.tb02858.x","article-title":"Nonconventional chondrosarcomas and chondrogenesis","volume":"9","author":"Vilanova","year":"1985","journal-title":"Histopathology"},{"key":"10.1053\/hupa.2001.28226_bib35","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1159\/000112360","article-title":"Peripherin, a new member of the intermediate filament protein family","volume":"6","author":"Portier","year":"1983","journal-title":"Dev Neurosci"},{"key":"10.1053\/hupa.2001.28226_bib36","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1242\/dev.124.16.3077","article-title":"Early and late-migrating cranial neural crest populations have equivalent developmental potential in vivo","volume":"124","author":"Baker","year":"1997","journal-title":"Development"},{"key":"10.1053\/hupa.2001.28226_bib37","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1038\/295063a0","article-title":"S-100 protein in human chondrocytes","volume":"295","author":"Stefansson","year":"1982","journal-title":"Nature"},{"key":"10.1053\/hupa.2001.28226_bib38","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1002\/(SICI)1097-0142(19970515)79:10<1903::AID-CNCR10>3.0.CO;2-Z","article-title":"Myxoid chondrosarcoma (chordoid sarcoma) of bone; a report of two cases and review of the literature","volume":"79","author":"Kilpatrick","year":"1997","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28226_bib39","first-page":"269","article-title":"Iatrogenic lesions","author":"Fechner","year":"1997"},{"key":"10.1053\/hupa.2001.28226_bib40","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0165-4608(93)90080-6","article-title":"Biologic and clinical significance of cytogenetic and molecular cytogenetic abnormalities in benign and malignant cartilaginous lesions","volume":"69","author":"Bridge","year":"1993","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1053\/hupa.2001.28226_bib41","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1097\/00022744-199706000-00001","article-title":"Extraskeletal myxoid chondrosarcoma: An immunohistochemical reappraisal of 39 cases","volume":"5","author":"Dei Tos","year":"1997","journal-title":"Appl Immunohistochem"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817701574821?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817701574821?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T05:27:23Z","timestamp":1621142843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817701574821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2001,10]]}},"alternative-id":["S0046817701574821"],"URL":"https:\/\/doi.org\/10.1053\/hupa.2001.28226","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2001,10]]}}}