{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:43:12Z","timestamp":1790908992128,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2001,10]]},"DOI":"10.1053\/hupa.2001.28245","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T03:46:10Z","timestamp":1030247170000},"page":"1087-1093","source":"Crossref","is-referenced-by-count":117,"title":["Cytokeratin 7 and 20 and thyroid transcription factor 1 can help distinguish pulmonary from gastrointestinal carcinoid and pancreatic endocrine tumors"],"prefix":"10.1053","volume":"32","author":[{"given":"Yun-Cai","family":"Cai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Banner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Glickman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D.","family":"Odze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/hupa.2001.28245_bib1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(82)90400-7","article-title":"The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells","volume":"31","author":"Moll","year":"1982","journal-title":"Cell"},{"key":"10.1053\/hupa.2001.28245_bib2","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1083\/jcb.111.2.567","article-title":"Identification of protein IT of the intestinal cytokeratin as a novel type I cytokeratin with unusual properties and expression patterns","volume":"111","author":"Moll","year":"1990","journal-title":"J Cell Biol"},{"key":"10.1053\/hupa.2001.28245_bib3","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1111\/j.1365-2559.1986.tb02574.x","article-title":"An analysis of the sensitivity and specificity of the cytokeratin marker CAM 5.2 for epithelial tumors. Results of a study of 203 sarcomas, 50 carcinomas and 28 malignant melanomas","volume":"10","author":"Leader","year":"1986","journal-title":"Histopathology"},{"key":"10.1053\/hupa.2001.28245_bib4","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1111\/j.1600-0560.1996.tb01472.x","article-title":"Intermediate- and low-molecular-weight keratin detection with the monoclonal antibody MNF116. An immunohistochemical study on 232 paraffin-embedded cutaneous lesions","volume":"23","author":"Prieto","year":"1996","journal-title":"J Cutan Pathol"},{"key":"10.1053\/hupa.2001.28245_bib5","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1038\/modpathol.3880175","article-title":"Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases","volume":"13","author":"Chu","year":"2000","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28245_bib6","first-page":"384","article-title":"Keratin 20: Immunohistochemical marker for gastrointestinal, urothelial, and Merkel cell carcinomas","volume":"8","author":"Miettinen","year":"1995","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28245_bib7","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1016\/S1357-2725(97)00007-1","article-title":"Thyroid transcription factor-1","volume":"29","author":"Bingle","year":"1997","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1053\/hupa.2001.28245_bib8","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0046-8177(99)90096-5","article-title":"Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesathelioma","volume":"30","author":"Khoor","year":"1999","journal-title":"Hum Pathol"},{"key":"10.1053\/hupa.2001.28245_bib9","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1242\/dev.113.4.1093","article-title":"The transcription factor TTF-11 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the fetal brain","volume":"113","author":"Lazzaro","year":"1991","journal-title":"Development"},{"key":"10.1053\/hupa.2001.28245_bib10","doi-asserted-by":"crossref","first-page":"5671","DOI":"10.1128\/MCB.14.9.5671","article-title":"The lung-specific protein B promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating commong factors for organ specific gene expression along the foregut axis","volume":"14","author":"Bohinski","year":"1994","journal-title":"Mol Cell Biol"},{"key":"10.1053\/hupa.2001.28245_bib11","doi-asserted-by":"crossref","first-page":"6531","DOI":"10.1074\/jbc.270.12.6531","article-title":"Lung cell specific expression of the murine surfactant protein A (SP-A) gene is mediated by interaction between the SP-A promoter and thyroid transcription factor-1","volume":"270","author":"Bruno","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1053\/hupa.2001.28245_bib12","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S0167-4781(96)00180-7","article-title":"Regulation of clara cell secretory protein gene transcription by thyroid transcription factor-1","volume":"1350","author":"Zhan","year":"1997","journal-title":"Biochim Biophys Acta"},{"key":"10.1053\/hupa.2001.28245_bib13","first-page":"427","article-title":"Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies","volume":"140","author":"Moll","year":"1992","journal-title":"Am J Pathol"},{"key":"10.1053\/hupa.2001.28245_bib14","first-page":"641","article-title":"Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas","volume":"136","author":"Ramaekers","year":"1990","journal-title":"Am J Pathol"},{"key":"10.1053\/hupa.2001.28245_bib15","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1093\/ajcp\/102.6.764","article-title":"Utility of cytokeratin immunostaining in separating pulmonary adenocarcinomas from colonic adenocarcinomas","volume":"102","author":"Loy","year":"1994","journal-title":"Am J Clin Pathol"},{"key":"10.1053\/hupa.2001.28245_bib16","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1097\/00125480-200007020-00007","article-title":"Thyroid transcription factor-1 is a marker of lung and thyroid carcinomas","volume":"7","author":"Ordonez","year":"2000","journal-title":"Adv Anat Pathol"},{"key":"10.1053\/hupa.2001.28245_bib17","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/00000478-200004000-00016","article-title":"Value of thyroid transcription factor-1, E-cadherin, BG8, WT1, AND CD44S immunostaining in distinguishing epithelial pleural mesothelioma from pulmonary and nonpulmonary adenocarcinoma","volume":"24","author":"Ordonez","year":"2000","journal-title":"Am J Surg Pathol"},{"key":"10.1053\/hupa.2001.28245_bib18","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/BF00199342","article-title":"Revised classification of neuroendocrine tumors of the lung, pancreas and gut","volume":"425","author":"Capella","year":"1995","journal-title":"Virchows Arch"},{"key":"10.1053\/hupa.2001.28245_bib19","series-title":"Manual for Staging of Cancer","author":"Bearhrs","year":"1988"},{"key":"10.1053\/hupa.2001.28245_bib20","doi-asserted-by":"crossref","first-page":"30","DOI":"10.5858\/2000-124-0030-PFTEOS","article-title":"Protocol for the examination of specimens from patients with endocrine tumors of the pancreas, including those with mixed endocrine and acinar cell differentiation","volume":"124","author":"Compton","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"10.1053\/hupa.2001.28245_bib21","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/modpathol.3880044","article-title":"Thyroid transcription factor-1 is expressed in extrapulmonary small cell carcinomas but not in other extrapulmonary neuroendocrine tumors","volume":"13","author":"Agoff","year":"2000","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28245_bib22","first-page":"5","article-title":"Thyroid transcription factor-1: Immunohistochemical evaluation in pulmonary neuroendocrine tumors","volume":"12","author":"Folpe","year":"1999","journal-title":"Mod Pathol"},{"key":"10.1053\/hupa.2001.28245_bib23","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1046\/j.1365-2559.2000.00890.x","article-title":"Expression of thyroid transcription factor-1 in pulmonary and extrapulmonary small cell carcinomas and other neuroendocrine carcinomas of various primary sites","volume":"36","author":"Kaufmann","year":"2000","journal-title":"Histopathology"},{"key":"10.1053\/hupa.2001.28245_bib24","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1097\/00000478-198207000-00001","article-title":"Retrospective study of pancreatic endocrine tumors using the immunoperoxidase method","volume":"6","author":"Mukai","year":"1982","journal-title":"Am J Surg Pathol"},{"key":"10.1053\/hupa.2001.28245_bib25","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1002\/1097-0142(19900101)65:1<135::AID-CNCR2820650127>3.0.CO;2-A","article-title":"Rectal and colonic carcinoids. A clinicopathologic study of 84 cases","volume":"65","author":"Federspiel","year":"1990","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28245_bib26","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1002\/1097-0142(19830515)51:10<1918::AID-CNCR2820511027>3.0.CO;2-Y","article-title":"The neuroendocrine products of intestinal carcinoids. An immunoperoxidase study of 35 carcinoid tumors stained for serotonin and eight polypeptide hormones","volume":"51","author":"Yang","year":"1983","journal-title":"Cancer"},{"key":"10.1053\/hupa.2001.28245_bib27","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/bjc.1988.304","article-title":"Immunoreactivity of various peptides in typical and atypical bronchopulmonary carcinoid tumors","volume":"58","author":"Al-Safar","year":"1988","journal-title":"Br J Cancer"},{"key":"10.1053\/hupa.2001.28245_bib28","first-page":"3221","article-title":"Cytokeratins in different types of human lung cancer as monitored by chain-specific monoclonal antibodies","volume":"48","author":"Broers","year":"1988","journal-title":"Cancer Res"},{"key":"10.1053\/hupa.2001.28245_bib29","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3109\/02841869309083901","article-title":"Cytokeratin expression in small intestinal and appendiceal carcinoids. A basis for classification","volume":"32","author":"Wilander","year":"1993","journal-title":"Acta Oncol"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817701958691?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817701958691?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,16]],"date-time":"2021-05-16T05:27:19Z","timestamp":1621142839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817701958691"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2001,10]]}},"alternative-id":["S0046817701958691"],"URL":"https:\/\/doi.org\/10.1053\/hupa.2001.28245","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2001,10]]}}}