{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T08:15:28Z","timestamp":1791274528547,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2003,3,1]],"date-time":"2003-03-01T00:00:00Z","timestamp":1046476800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Human Pathology"],"published-print":{"date-parts":[[2003,3]]},"DOI":"10.1053\/hupa.2003.36","type":"journal-article","created":{"date-parts":[[2003,4,7]],"date-time":"2003-04-07T20:06:02Z","timestamp":1049745962000},"page":"285-289","source":"Crossref","is-referenced-by-count":61,"title":["Chloroquine-induced phospholipidosis of the kidney mimicking fabry's disease: Case report and review of the literature"],"prefix":"10.1053","volume":"34","author":[{"given":"J.","family":"M\u0169ller-H\u00f5cker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Dendorfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.S.","family":"Braun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1053\/hupa.2003.36_bib1","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1056\/NEJM199102073240607","article-title":"An atypical variant of Fabry's disease with manifestations confined to the myocardium","volume":"324","author":"Von Scheidt","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1053\/hupa.2003.36_bib2","first-page":"86","article-title":"Atypical Fabry's disease: An oligosymptomatic variant","volume":"120","author":"Ko","year":"1996","journal-title":"Arch Pathol Lab Med"},{"key":"10.1053\/hupa.2003.36_bib3","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/0272-6386(95)90061-6","article-title":"A female heterozygous patient with Fabry's disease with renal accumulation of trihexosylceramide detected with a monoclonal antibody","volume":"26","author":"Fukushima","year":"1995","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/hupa.2003.36_bib4","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1097\/00000478-197906000-00003","article-title":"Fabry's disease: Primary diagnosis by electron microscopy","volume":"3","author":"Schatzki","year":"1979","journal-title":"Am J Surg Pathol"},{"issue":"suppl 2","key":"10.1053\/hupa.2003.36_bib5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1023\/A:1012423924648","article-title":"Renal pathological changes in Fabry disease","volume":"24","author":"Sessa","year":"2001","journal-title":"J Inherit Metab Dis"},{"key":"10.1053\/hupa.2003.36_bib6","first-page":"62","article-title":"Drug-induced and naturally occuring myeloid bodies","volume":"27","author":"Hruban","year":"1972","journal-title":"Lab Invest"},{"key":"10.1053\/hupa.2003.36_bib7","first-page":"49","article-title":"Drug-induced lysosomal storage disorders","author":"L\u00fcllmann-Rauch","year":"1979"},{"key":"10.1053\/hupa.2003.36_bib8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/10408447509164014","article-title":"Drug-induced phospholipidosis","volume":"4","author":"L\u00fcllmann","year":"1975","journal-title":"CRC Crit Rev Toxicol"},{"key":"10.1053\/hupa.2003.36_bib9","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1016\/0002-8703(83)90016-9","article-title":"Side effects and possible contraindications of amiodarone use","volume":"106","author":"Harris","year":"1983","journal-title":"Am Heart J"},{"key":"10.1053\/hupa.2003.36_bib10","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/0002-9343(85)90346-8","article-title":"Electron microscopic demonstration of lysosomal inclusion bodies in lung, liver, lymph nodes and blood leukocytes of patients with amiodarone pulmonary toxicity","volume":"78","author":"Dake","year":"1985","journal-title":"Am J Med"},{"key":"10.1053\/hupa.2003.36_bib11","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1136\/thx.41.2.100","article-title":"Amiodarone toxicity: Functional and ultrastructural evaluation","volume":"41","author":"Liu","year":"1986","journal-title":"Thorax"},{"key":"10.1053\/hupa.2003.36_bib12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0046-8177(90)90076-H","article-title":"Histopathologic analysis of suspected amiodarone hepatotoxicity","volume":"21","author":"Lewis","year":"1990","journal-title":"HUM PATHOL"},{"key":"10.1053\/hupa.2003.36_bib13","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1365-2559.1993.tb00076.x","article-title":"Amiodarone-associated cirrhosis with hepatic and lymph node granulomas","volume":"22","author":"Harrison","year":"1993","journal-title":"Histopathology"},{"key":"10.1053\/hupa.2003.36_bib14","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0002-9149(91)90915-8","article-title":"Endomyocardial biopsy finding in two patients with idiopathic dilated cardiomyopathy receiving long-term treatment with amiodarone","volume":"67","author":"Arbustini","year":"1991","journal-title":"Am J Cardiol"},{"key":"10.1053\/hupa.2003.36_bib15","first-page":"64","article-title":"Chloroquine keratopathy as an example of drug-induced phospholipidosis","volume":"170","author":"Seiler","year":"1977","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"10.1053\/hupa.2003.36_bib16","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1056\/NEJM198701223160405","article-title":"Diagnosis of choloroquine cardiomyopathy by endomyocardial biopsy","volume":"316","author":"Ratliff","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1053\/hupa.2003.36_bib17","first-page":"953","article-title":"Choloroquine cardiomyopathy","volume":"111","author":"McAllister","year":"1989","journal-title":"Arch Pathol Lab Med"},{"key":"10.1053\/hupa.2003.36_bib18","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1111\/j.0954-6820.1977.tb16857.x","article-title":"Cardiomyopathy after choloroquine treatment","volume":"202","author":"Magnussen","year":"1977","journal-title":"Acta Med Scand"},{"key":"10.1053\/hupa.2003.36_bib19","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1136\/hrt.69.5.451","article-title":"Restrictive cardiomyopathy caused by choloroquine","volume":"69","author":"Iglesias","year":"1993","journal-title":"Br Heart J"},{"key":"10.1053\/hupa.2003.36_bib20","first-page":"1221","article-title":"Choloroquine-related cardiac toxicity","volume":"25","author":"Veinot","year":"1998","journal-title":"J Rheumatol"},{"key":"10.1053\/hupa.2003.36_bib21","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0304-3940(94)90785-4","article-title":"Immunohistochemical evidence for amyloid beta in rat soleus muscle in choloroquine-induced myopathy","volume":"182","author":"Tsuzuki","year":"1994","journal-title":"Neurosci Lett"},{"key":"10.1053\/hupa.2003.36_bib22","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1097\/00005072-199807000-00003","article-title":"Accumulation of tau in autophagic vacuoles in chloroquine myopathy","volume":"57","author":"Murakami","year":"1998","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1053\/hupa.2003.36_bib23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/rheumatology\/34.2.166","article-title":"Incidence of myopathy in patients treated with antimalarials: A report of the cases and a review of the literature","volume":"34","author":"Avina-Zubieta","year":"1995","journal-title":"Br J Rheumatol"},{"key":"10.1053\/hupa.2003.36_bib24","first-page":"2927","article-title":"Hydroxychloroquine neuromyotoxicity","volume":"27","author":"Stein","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1053\/hupa.2003.36_bib25","first-page":"1289","article-title":"Heritable metabolic diseases","author":"Bernstein","year":"1998"},{"key":"10.1053\/hupa.2003.36_bib26","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1750-3639.1996.tb00850.x","article-title":"Neuronal ceroid-lipofuscinosis\u2014late-infantile or Jansky-Bielschowsky type revisited","volume":"6","author":"Goebel","year":"1996","journal-title":"Brain Pathol"},{"key":"10.1053\/hupa.2003.36_bib27","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1093\/ndt\/16.12.2328","article-title":"Clinical and morphological features of kidney involvement in primary Sj\u00f6gren's syndrome","volume":"16","author":"Bossini","year":"2001","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/hupa.2003.36_bib28","first-page":"2703","article-title":"Hydrochloroquine retinopathy despite regular ophthalmologic evaluation: a consecutive series","volume":"27","author":"Bienfang","year":"2000","journal-title":"J Rheumatol"},{"key":"10.1053\/hupa.2003.36_bib29","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1001\/archneur.1989.00520400124033","article-title":"Myasthenic syndrome caused by direct effect of chloroquine on neuromuscular junction","volume":"46","author":"Robberecht","year":"1989","journal-title":"Arch Neurol"},{"key":"10.1053\/hupa.2003.36_bib30","first-page":"246","article-title":"Basic cellular lesion in choloroquine toxicity","volume":"24","author":"Read","year":"1971","journal-title":"Lab Invest"},{"key":"10.1053\/hupa.2003.36_bib31","first-page":"323","article-title":"The metabolism of chloroquine in man during or after repeated oral dosage","volume":"158","author":"McChesney","year":"1967","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1053\/hupa.2003.36_bib32","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1159\/000166730","article-title":"Silicon nephropathy mimicking Fabry's disease","volume":"3","author":"Banks","year":"1983","journal-title":"J Nephrol"},{"key":"10.1053\/hupa.2003.36_bib33","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1016\/0006-2952(74)90174-9","article-title":"Lysosomotropic agents","volume":"23","author":"de Duve","year":"1974","journal-title":"Biochem Pharmacol"},{"key":"10.1053\/hupa.2003.36_bib34","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1083\/jcb.63.2.430","article-title":"Protein degradation in cultured cells. II. The uptake of choloroquine by rat fibroblasts and the inhibition of cellular protein degradation and cathepsin B","volume":"63","author":"Wibo","year":"1974","journal-title":"J Cell Biol"},{"key":"10.1053\/hupa.2003.36_bib35","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/235050a0","article-title":"Lysosomes, pH and the antimalarial action of choloroquine","volume":"235","author":"Homewood","year":"1972","journal-title":"Nature"},{"key":"10.1053\/hupa.2003.36_bib36","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0014-4886(81)90090-X","article-title":"Inhibition of lysosomal function in red and white skeletal muscles by choloroquine","volume":"71","author":"Stauber","year":"1981","journal-title":"Exp Neurol"},{"key":"10.1053\/hupa.2003.36_bib37","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/00005072-197007000-00010","article-title":"Experimental choloroquine myopathy","volume":"29","author":"MacDonald","year":"1970","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1053\/hupa.2003.36_bib38","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0040-8166(81)90013-6","article-title":"Increased autophagy in choloroquine treated tonic and phasic muscles; an alternative view","volume":"13","author":"Trout","year":"1981","journal-title":"Tissue Cell"},{"key":"10.1053\/hupa.2003.36_bib39","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.1016\/0006-2952(82)90295-7","article-title":"Studies on mechanism of phospholipid storage induced by amantadine and choloroquine in Madin Darby canine kidney cells","volume":"3","author":"Hostetler","year":"1982","journal-title":"Biochem Pharmacol"},{"key":"10.1053\/hupa.2003.36_bib40","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/BF00223481","article-title":"Amiodarone, an inhibitor of phospholipase activity: A comprehensive study of the inhibitory effects of amiodarone, choloroquine and chlorpromazine","volume":"76","author":"Shaikh","year":"1987","journal-title":"Mol Cell Biochem"},{"key":"10.1053\/hupa.2003.36_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-2760(87)90276-1","article-title":"Effect of choloroquine on the activity of some lysosomal enzymes involved in ganglioside degradation","volume":"917","author":"Fredman","year":"1987","journal-title":"Biochem Biophys Acta"},{"key":"10.1053\/hupa.2003.36_bib42","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF00249690","article-title":"The in vivo inhibition of transport enzyme activities by choloroquine in different organs of rat is reversible","volume":"118","author":"Chandra","year":"1992","journal-title":"Mol Cell Biochem"},{"key":"10.1053\/hupa.2003.36_bib43","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/phrs.1996.0108","article-title":"Choloroquine is a potent inhibitor of glutamate dehydrogenase in liver and kindney-cortex of rabbit","volume":"35","author":"Jarzyna","year":"1997","journal-title":"Pharmacol Res"},{"key":"10.1053\/hupa.2003.36_bib44","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0232-1513(85)80023-2","article-title":"Effect of choloroquine on hepatocytic organelles in rat","volume":"28","author":"Singh","year":"1985","journal-title":"Exp Pathol"},{"key":"10.1053\/hupa.2003.36_bib45","doi-asserted-by":"crossref","first-page":"221","DOI":"10.3109\/08860229409044862","article-title":"The effects of oral choloroquine administration on kidney function","volume":"16","author":"Musabayane","year":"1994","journal-title":"Renal Failure"},{"key":"10.1053\/hupa.2003.36_bib46","first-page":"34","article-title":"Antimalarial drug induced decrease in creatinine clearance","volume":"22","author":"Landewe","year":"1995","journal-title":"J Rheumatol"},{"key":"10.1053\/hupa.2003.36_bib47","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/BF01954851","article-title":"Studies on correlation between chloroquine induced tissue damage and serum enzyme changes in the rat","volume":"45","author":"Ngha","year":"1989","journal-title":"Experientia"},{"key":"10.1053\/hupa.2003.36_bib48","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0741-8329(00)00110-5","article-title":"Effects of ethanol on the changes in renal fluid and electrolyte handling and kidney morphology induced by long-term choloroquine administration to rats","volume":"22","author":"Musabayane","year":"2000","journal-title":"Alcohol"},{"key":"10.1053\/hupa.2003.36_bib49","first-page":"72","article-title":"Toxic effects of chloroquine on the ultrastructure of the kidney of the rat","volume":"2","author":"Goewonyo","year":"1975","journal-title":"West Afr J Pharmocol Drug Res"},{"key":"10.1053\/hupa.2003.36_bib50","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0306-4492(82)90176-9","article-title":"Effect of choloroquine on the stability of rat kidney lysosomes in vivo and in vitro","volume":"73","author":"Ngha","year":"1982","journal-title":"Comp Biochem Physiol C"},{"key":"10.1053\/hupa.2003.36_bib51","first-page":"258","article-title":"Nephrotoxicity of choloroquine: A light and electron microscopic study","volume":"7","author":"Datsis","year":"1972","journal-title":"Exp Pathol"},{"key":"10.1053\/hupa.2003.36_bib52","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/S0891-5849(96)00285-7","article-title":"Effects of choloroquine treatment on antioxidant enzymes in rat liver and kidney","volume":"22","author":"Magwere","year":"1997","journal-title":"Free Radic Biol Med"}],"container-title":["Human Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817702297361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0046817702297361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,3,24]],"date-time":"2019-03-24T09:53:03Z","timestamp":1553421183000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0046817702297361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,3]]},"references-count":52,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,3]]}},"alternative-id":["S0046817702297361"],"URL":"https:\/\/doi.org\/10.1053\/hupa.2003.36","relation":{},"ISSN":["0046-8177"],"issn-type":[{"value":"0046-8177","type":"print"}],"subject":[],"published":{"date-parts":[[2003,3]]}}}