{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T17:10:30Z","timestamp":1771002630062,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2003,12,1]],"date-time":"2003-12-01T00:00:00Z","timestamp":1070236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2003,12,1]],"date-time":"2003-12-01T00:00:00Z","timestamp":1070236800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2003,12]]},"DOI":"10.1053\/j.ajkd.2003.08.032","type":"journal-article","created":{"date-parts":[[2003,12,2]],"date-time":"2003-12-02T13:07:31Z","timestamp":1070370451000},"page":"1287-1292","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"title":["Two male siblings with hereditary renal hypouricemia and exercise-induced ARF"],"prefix":"10.1053","volume":"42","author":[{"given":"Motoko","family":"Tanaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuko","family":"Itoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazutaka","family":"Matsushita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Wakita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masataka","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Nonoguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichiro","family":"Kitamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Hosoyamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Endou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimio","family":"Tomita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1053\/j.ajkd.2003.08.032_BIB1","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/S0272-6386(98)70067-8","article-title":"Regulation of renal urate excretion","volume":"32","author":"Maesaka","year":"1998","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000421446","article-title":"Renal hypouricemia","volume":"100","author":"Sperling","year":"1992","journal-title":"Contrib Nephrol"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB3","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2169\/internalmedicine.36.201","article-title":"Two cases of renal hypouricemia with nephrolithiasis","volume":"36","author":"Hirasaki","year":"1997","journal-title":"Intern Med"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB4","first-page":"467","article-title":"Patients with renal hypouricemia with exercise-induced acute renal failure and chronic renal dysfunction","volume":"53","author":"Kikuchi","year":"2000","journal-title":"Clin Nephrol"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB5","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/BF01892900","article-title":"Acute renal failure due to uric acid nephropathy in a patient with renal hypouricemia","volume":"67","author":"Erley","year":"1989","journal-title":"Klin Wochenshr"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB6","first-page":"923","article-title":"Exercise-induced acute renal failure in 3 patients with renal hypouricemia","volume":"32","author":"Ishikawa","year":"1990","journal-title":"Jpn J Nephrol"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB7","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1111\/j.1651-2227.1996.tb14206.x","article-title":"Recurrent exercise-induced acute renal failure in renal hypouricemia","volume":"85","author":"Ninomiya","year":"1996","journal-title":"Acta Paediatr"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB8","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1007\/BF00853226","article-title":"Acute renal failure after exercise in a child with renal hypouricemia","volume":"7","author":"Igarashi","year":"1993","journal-title":"Pediatr Nephrol"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB9","first-page":"1384","article-title":"Acute renal failure after a mild physical exercise in idiopathic renal hypouricemia","volume":"8","author":"Kihara","year":"1993","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB10","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1093\/ndt\/15.1.104","article-title":"A case of exercise-induced acute renal failure in a patient with enhanced renal hypouricemia","volume":"15","author":"Kurihara","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB11","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1442-200X.1995.tb03394.x","article-title":"Acute renal failure after exercise in a child with renal hypouricemia","volume":"37","author":"Fujieda","year":"1995","journal-title":"Acta Paediatr Jpn"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/j.1442-200X.1998.tb01413.x","article-title":"Exercise-induced acute renal failure in a girl with renal hypouricemia","volume":"40","author":"Sato","year":"1998","journal-title":"Acta Paediatr Jpn"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB13","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1093\/ndt\/13.4.994","article-title":"Exercise-induced acute renal failure in a patient with congenital renal hypouricemia","volume":"13","author":"Yim","year":"1998","journal-title":"Nephrol Dial Transplant"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB14","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/nature742","article-title":"Molecular identification of a renal urate anion exchanger that regulates blood urate levels","volume":"417","author":"Enomoto","year":"2002","journal-title":"Nature"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB15","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/0002-9343(67)90245-8","article-title":"The renal mechanism for urate homeostasis in normal man","volume":"43","author":"Steel","year":"1967","journal-title":"Am J Med"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB16","doi-asserted-by":"crossref","first-page":"239","DOI":"10.7326\/0003-4819-78-2-239","article-title":"The clinical significance of hypouricemia","volume":"78","author":"Ramsdell","year":"1973","journal-title":"Ann Intern Med"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB17","first-page":"211","article-title":"Prevalencia, fisiopatologia y procesos asociados a hipouricemia en una poblacion hospitalaria","volume":"186","author":"Casas","year":"1990","journal-title":"Rev Clin Esp"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB18","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1002\/art.1780180715","article-title":"Hypouricemia","volume":"18","author":"Kelly","year":"1975","journal-title":"Arthritis Rheum"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB19","first-page":"865","article-title":"Hypouricemia; With evidence for tubular elimination of uric acid","volume":"35","author":"Praetorius","year":"1950","journal-title":"J Lab Clin Med"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/0002-9343(72)90181-7","article-title":"Hypouricemia due isolated renal tubular defect","volume":"53","author":"Green","year":"1972","journal-title":"Am J Med"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB21","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1136\/jcp.33.10.971","article-title":"Familial hypouricemia and uric acid calculi","volume":"33","author":"Hedley","year":"1980","journal-title":"J Clin Pathol"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB22","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1172\/JCI112004","article-title":"Paradoxical effects of pyrazinoate and nicotinate on urate transport in dog renal microvillus membranes","volume":"76","author":"Guggino","year":"1985","journal-title":"Clin Invest"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB23","first-page":"F61","article-title":"Indirect coupling of urate and p-aminohippurate transport to sodium in human brush-border membrane vesicles","author":"Roch-Ramel","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB24","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/0272-6386(95)90579-0","article-title":"Renal hypouricemia","volume":"25","author":"Yeun","year":"1995","journal-title":"Am J Kidney Dis"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB25","series-title":"Acute Renal Failure","first-page":"224","article-title":"Acute renal failure with severe loin pain and patchy renal vasoconstriction","author":"Ichikawa","year":"1982"},{"key":"10.1053\/j.ajkd.2003.08.032_BIB26","first-page":"207","article-title":"Patients with renal hypouricemia are prone to develop acute renal failure-why?","volume":"43","author":"Murakami","year":"1995","journal-title":"Clin Nephrol"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638603011193?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638603011193?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T01:21:55Z","timestamp":1759454515000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638603011193"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,12]]},"references-count":26,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2003,12]]}},"alternative-id":["S0272638603011193"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2003.08.032","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2003,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two male siblings with hereditary renal hypouricemia and exercise-induced ARF","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2003.08.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2003 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}