{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T14:55:17Z","timestamp":1771340117021,"version":"3.50.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1053\/j.ajkd.2009.12.023","type":"journal-article","created":{"date-parts":[[2010,2,27]],"date-time":"2010-02-27T04:31:15Z","timestamp":1267245075000},"page":"916-922","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Carbohydrate Antigen 19-9 as a Diagnostic Marker for Hepatic Cyst Infection in Autosomal Dominant Polycystic Kidney Disease"],"prefix":"10.1053","volume":"55","author":[{"given":"Nada","family":"Kanaan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Goffin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yves","family":"Pirson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivier","family":"Devuyst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziad","family":"Hassoun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1053\/j.ajkd.2009.12.023_bib1","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1681\/ASN.V1191767","article-title":"Liver involvement in autosomal-dominant polycystic kidney disease: therapeutic dilemma","volume":"11","author":"Chauveau","year":"2000","journal-title":"J Am Soc Nephrol."},{"key":"10.1053\/j.ajkd.2009.12.023_bib2","doi-asserted-by":"crossref","unstructured":"Torres VE, Harris PC, Pirson Y. Autosomal dominant polycystic kidney disease. Lancet. 369(9569):1287-1301.","DOI":"10.1016\/S0140-6736(07)60601-1"},{"issue":"7","key":"10.1053\/j.ajkd.2009.12.023_bib3","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1016\/S0025-6196(12)65154-4","article-title":"Hepatic cyst infection in autosomal dominant polycystic kidney disease","volume":"65","author":"Telenti","year":"1990","journal-title":"Mayo Clin Proc."},{"issue":"1","key":"10.1053\/j.ajkd.2009.12.023_bib4","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1093\/ndt\/gfm665","article-title":"Renal cyst infection in autosomal dominant polycystic kidney disease","volume":"23","author":"Migali","year":"2008","journal-title":"Nephrol Dial Transplant."},{"issue":"6","key":"10.1053\/j.ajkd.2009.12.023_bib5","doi-asserted-by":"crossref","first-page":"E18","DOI":"10.1016\/S0272-6386(03)00368-8","article-title":"Diagnosis of renal and hepatic cyst infections by 18-F-fluorodeoxyglucose positron emission tomography in autosomal dominant polycystic kidney disease","volume":"41","author":"Bleeker-Rovers","year":"2003","journal-title":"Am J Kidney Dis."},{"issue":"6","key":"10.1053\/j.ajkd.2009.12.023_bib6","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1007\/s12149-008-0150-3","article-title":"Diagnosis and localization of renal cyst infection by 18F-fluorodeoxyglucose PET\/CT in polycystic kidney disease","volume":"22","author":"Soussan","year":"2008","journal-title":"Ann Nucl Med."},{"issue":"4","key":"10.1053\/j.ajkd.2009.12.023_bib7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1046\/j.1440-1827.1999.00865.x","article-title":"An immunohistochemical study of hepatic atypical adenomatous hyperplasia, hepatocellular carcinoma, and cholangiocarcinoma with alpha-fetoprotein, carcinoembryonic antigen, CA19-9, epithelial membrane antigen, and cytokeratins 18 and 19","volume":"49","author":"Tsuji","year":"1999","journal-title":"Pathol Int."},{"issue":"7","key":"10.1053\/j.ajkd.2009.12.023_bib8","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1097\/00000478-198907000-00004","article-title":"Well-differentiated cholangiocarcinoma: diagnostic significance of morphologic and immunohistochemical parameters","volume":"13","author":"Nakajima","year":"1989","journal-title":"Am J Surg Pathol."},{"issue":"5","key":"10.1053\/j.ajkd.2009.12.023_bib9","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1046\/j.1365-2559.2002.01374.x","article-title":"Immunohistochemical localization of CEA, CA19-9 and DU-PAN-2 in hepatitis C virus-infected liver tissues","volume":"40","author":"Kitagawa","year":"2002","journal-title":"Histopathology"},{"key":"10.1053\/j.ajkd.2009.12.023_bib10","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1186\/1752-1947-2-329","article-title":"A simple hepatic cyst with elevated serum and cyst fluid CA19-9 levels: a case report","volume":"2","author":"Yanai","year":"2008","journal-title":"J Med Case Reports"},{"issue":"50","key":"10.1053\/j.ajkd.2009.12.023_bib11","first-page":"507","article-title":"Infected hepatic cyst","volume":"50","author":"Yoshida","year":"2003","journal-title":"Hepatogastroenterology"},{"issue":"6","key":"10.1053\/j.ajkd.2009.12.023_bib12","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-130-6-199903160-00002","article-title":"A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation","volume":"130","author":"Levey","year":"1999","journal-title":"Ann Intern Med."},{"issue":"46","key":"10.1053\/j.ajkd.2009.12.023_bib13","doi-asserted-by":"crossref","first-page":"29271","DOI":"10.1016\/S0021-9258(19)62041-7","article-title":"Molecular genetic analysis of the human Lewis histo-blood group system","volume":"269","author":"Nishihara","year":"1994","journal-title":"J Biol Chem."},{"issue":"suppl 4","key":"10.1053\/j.ajkd.2009.12.023_bib14","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1093\/annonc\/10.suppl_4.S145","article-title":"Role of tumour markers, cytogenetics","volume":"10","author":"Lamerz","year":"1999","journal-title":"Ann Oncol."},{"issue":"11","key":"10.1053\/j.ajkd.2009.12.023_bib15","first-page":"4820","article-title":"Gastrointestinal cancer-associated antigen in immunoperoxidase assay","volume":"42","author":"Atkinson","year":"1982","journal-title":"Cancer Res."},{"issue":"3","key":"10.1053\/j.ajkd.2009.12.023_bib16","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1309\/H52VET3M6P7GYWG1","article-title":"Performance characteristics of five automated CA 19-9 assays","volume":"127","author":"La'ulu","year":"2007","journal-title":"Am J Clin Pathol."},{"issue":"3","key":"10.1053\/j.ajkd.2009.12.023_bib17","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.ejso.2006.10.004","article-title":"Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer","volume":"33","author":"Goonetilleke","year":"2007","journal-title":"Eur J Surg Oncol."},{"issue":"6","key":"10.1053\/j.ajkd.2009.12.023_bib18","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1093\/ajcp\/99.6.726","article-title":"Distribution of CA 19-9 in adenocarcinomas and transitional cell carcinomas","volume":"99","author":"Loy","year":"1993","journal-title":"Am J Clin Pathol."},{"issue":"1","key":"10.1053\/j.ajkd.2009.12.023_bib19","first-page":"111","article-title":"Remarkably elevated serum levels of carbohydrate antigen 19-9 in cystic duct and common bile duct lithiasis","volume":"17","author":"Mimidis","year":"2008","journal-title":"J Gastrointest Liver Dis."},{"issue":"12","key":"10.1053\/j.ajkd.2009.12.023_bib20","doi-asserted-by":"crossref","first-page":"3213","DOI":"10.1007\/s10620-008-0289-8","article-title":"Elevation of carbohydrate antigen 19.9 in benign hepatobiliary conditions and its correlation with serum bilirubin concentration","volume":"53","author":"Ong","year":"2008","journal-title":"Dig Dis Sci."},{"issue":"pt 1","key":"10.1053\/j.ajkd.2009.12.023_bib21","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/000456329803500113","article-title":"The effect of benign and malignant liver disease on the tumour markers CA19-9 and CEA","volume":"35","author":"Maestranzi","year":"1998","journal-title":"Ann Clin Biochem."},{"issue":"5","key":"10.1053\/j.ajkd.2009.12.023_bib22","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1053\/ejso.1999.0925","article-title":"Elevated tumour marker CA19-9: clinical interpretation and influence of obstructive jaundice","volume":"26","author":"Mann","year":"2000","journal-title":"Eur J Surg Oncol."},{"issue":"4","key":"10.1053\/j.ajkd.2009.12.023_bib23","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1007\/s10620-005-2559-z","article-title":"Elevated CA 19-9 caused by Hashimoto's thyroiditis: review of the benign causes of increased CA 19-9 level","volume":"50","author":"Parra","year":"2005","journal-title":"Dig Dis Sci."},{"issue":"2","key":"10.1053\/j.ajkd.2009.12.023_bib24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/jcla.20136","article-title":"Serum levels of CA19-9 in patients with nonmalignant respiratory diseases","volume":"21","author":"Kodama","year":"2007","journal-title":"J Clin Lab Anal."},{"issue":"3","key":"10.1053\/j.ajkd.2009.12.023_bib25","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1093\/clinchem\/29.3.549","article-title":"Radioimmunometric assay for a monoclonal antibody-defined tumor marker, CA 19-9","volume":"29","author":"Del Villano","year":"1983","journal-title":"Clin Chem."},{"issue":"7","key":"10.1053\/j.ajkd.2009.12.023_bib26","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1111\/j.1572-0241.1999.01234.x","article-title":"A new strategy for the application of CA19-9 in the differentiation of pancreaticobiliary cancer: analysis using a receiver operating characteristic curve","volume":"94","author":"Kim","year":"1999","journal-title":"Am J Gastroenterol."},{"issue":"11","key":"10.1053\/j.ajkd.2009.12.023_bib27","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1007\/BF01299853","article-title":"Determination of tumor marker levels in cystic fluid of benign liver cysts","volume":"37","author":"Iwase","year":"1992","journal-title":"Dig Dis Sci."},{"issue":"4","key":"10.1053\/j.ajkd.2009.12.023_bib28","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1002\/hep.1840400404","article-title":"Polycystic disease of the liver","volume":"40","author":"Everson","year":"2004","journal-title":"Hepatology"},{"issue":"11","key":"10.1053\/j.ajkd.2009.12.023_bib29","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1111\/j.1442-2042.2006.01593.x","article-title":"Elevation of serum and urinary carbohydrate antigen 19-9 in benign hydronephrosis","volume":"13","author":"Aybek","year":"2006","journal-title":"Int J Urol."},{"issue":"2","key":"10.1053\/j.ajkd.2009.12.023_bib30","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.urology.2003.10.048","article-title":"Elevation of CA 19-9 in giant hydronephrosis induced by a renal calculus","volume":"63","author":"Meyer","year":"2004","journal-title":"Urology"},{"issue":"11","key":"10.1053\/j.ajkd.2009.12.023_bib31","doi-asserted-by":"crossref","first-page":"887","DOI":"10.2169\/internalmedicine.38.887","article-title":"Giant hydronephrosis due to a ureteral stone, and elevated serum levels of CA 19-9","volume":"38","author":"Shudo","year":"1999","journal-title":"Intern Med."},{"issue":"1","key":"10.1053\/j.ajkd.2009.12.023_bib32","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0022-5347(05)65372-4","article-title":"The correlation of serum carbohydrate antigen 19-9 with benign hydronephrosis","volume":"167","author":"Suzuki","year":"2002","journal-title":"J Urol."},{"issue":"1","key":"10.1053\/j.ajkd.2009.12.023_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000281648","article-title":"Immunohistochemical distribution of CA19-9 in normal and tumor tissues of the kidney","volume":"45","author":"Ohshio","year":"1990","journal-title":"Urol Int."},{"issue":"5","key":"10.1053\/j.ajkd.2009.12.023_bib34","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1177\/030089160108700513","article-title":"Extraordinarily elevated CA19-9 in benign conditions: a case report and review of the literature","volume":"87","author":"Akdogan","year":"2001","journal-title":"Tumori"},{"issue":"11","key":"10.1053\/j.ajkd.2009.12.023_bib35","doi-asserted-by":"crossref","first-page":"3140","DOI":"10.1007\/s10620-006-9164-7","article-title":"Extremely elevated CA19-9 in acute cholangitis","volume":"52","author":"Sheen-Chen","year":"2007","journal-title":"Dig Dis Sci."},{"issue":"3","key":"10.1053\/j.ajkd.2009.12.023_bib36","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1007\/s005950200037","article-title":"Diverticulitis causing a high serum level of carbohydrate antigen 19-9: report of a case","volume":"32","author":"Nakamura","year":"2002","journal-title":"Surg Today"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638609016618?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638609016618?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T01:54:58Z","timestamp":1759456498000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638609016618"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S0272638609016618"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2009.12.023","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Carbohydrate Antigen 19-9 as a Diagnostic Marker for Hepatic Cyst Infection in Autosomal Dominant Polycystic Kidney Disease","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2009.12.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}