{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T06:18:39Z","timestamp":1790230719160,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1053\/j.ajkd.2012.08.035","type":"journal-article","created":{"date-parts":[[2012,10,3]],"date-time":"2012-10-03T19:30:17Z","timestamp":1349292617000},"page":"271-278","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":106,"title":["Anatomic Brain Disease in Hemodialysis Patients: A Cross-sectional Study"],"prefix":"10.1053","volume":"61","author":[{"given":"David A.","family":"Drew","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafeeque","family":"Bhadelia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hocine","family":"Tighiouart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vera","family":"Novak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tammy M.","family":"Scott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina V.","family":"Lou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Shaffi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel E.","family":"Weiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Sarnak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1046\/j.1523-1755.2003.00101.x","article-title":"Elevated risk of stroke among patients with end-stage renal disease","volume":"64","author":"Seliger","year":"2003","journal-title":"Kidney Int"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib2","doi-asserted-by":"crossref","first-page":"129","DOI":"10.5414\/CNP64129","article-title":"Influence of hemodialysis on the mean blood flow velocity in the middle cerebral artery","volume":"64","author":"Stefanidis","year":"2005","journal-title":"Clin Nephrol"},{"issue":"1","key":"10.1053\/j.ajkd.2012.08.035_bib3","doi-asserted-by":"crossref","first-page":"c23","DOI":"10.1159\/000077592","article-title":"Dialysis-related hypotension as a cause of progressive frontal lobe atrophy in chronic hemodialysis patients: a 3-year prospective study","volume":"97","author":"Mizumasa","year":"2004","journal-title":"Nephron Clin Pract"},{"issue":"12","key":"10.1053\/j.ajkd.2012.08.035_bib4","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.1097\/HJH.0b013e32833eaf49","article-title":"Traditional and nontraditional risk factors as predictors of cerebrovascular events in patients with end stage renal disease","volume":"28","author":"Tripepi","year":"2010","journal-title":"J Hypertens"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib5","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1161\/01.STR.0000052631.98405.15","article-title":"Incidence and risk factors of silent brain infarcts in the population-based Rotterdam Scan Study","volume":"34","author":"Vermeer","year":"2003","journal-title":"Stroke"},{"issue":"10","key":"10.1053\/j.ajkd.2012.08.035_bib6","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1161\/01.STR.19.10.1285","article-title":"White matter signal abnormalities in normal individuals: correlation with carotid ultrasonography, cerebral blood flow measurements, and cerebrovascular risk factors","volume":"19","author":"Fazekas","year":"1988","journal-title":"Stroke"},{"issue":"8","key":"10.1053\/j.ajkd.2012.08.035_bib7","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1161\/01.STR.0000132193.35955.69","article-title":"White matter hyperintensity on cranial magnetic resonance imaging","volume":"35","author":"Kuller","year":"2004","journal-title":"Stroke"},{"issue":"9406","key":"10.1053\/j.ajkd.2012.08.035_bib8","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S0140-6736(04)15441-X","article-title":"Imaging cerebral atrophy: normal ageing to Alzheimer's disease","volume":"363","author":"Fox","year":"2004","journal-title":"Lancet"},{"issue":"3","key":"10.1053\/j.ajkd.2012.08.035_bib9","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1212\/WNL.42.3.527","article-title":"Quantitative cerebral anatomy of the aging human brain","volume":"42","author":"Coffey","year":"1992","journal-title":"Neurology"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib10","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0197-4580(00)00238-4","article-title":"Hippocampal volume discriminates between normal cognition; questionable and mild dementia in the elderly","volume":"22","author":"Wolf","year":"2001","journal-title":"Neurobiol Aging"},{"issue":"9","key":"10.1053\/j.ajkd.2012.08.035_bib11","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1001\/archneur.57.9.1295","article-title":"How complex interactions of ischemic brain infarcts, white matter lesions, and atrophy relate to poststroke dementia","volume":"57","author":"Pohjasvaara","year":"2000","journal-title":"Arch Neurol"},{"issue":"12","key":"10.1053\/j.ajkd.2012.08.035_bib12","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1212\/WNL.43.12.2490","article-title":"Neuropsychologic correlates of MRI white matter hyperintensities","volume":"43","author":"Schmidt","year":"1993","journal-title":"Neurology"},{"issue":"6","key":"10.1053\/j.ajkd.2012.08.035_bib13","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1161\/01.STR.25.6.1109","article-title":"Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging","volume":"25","author":"Breteler","year":"1994","journal-title":"Stroke"},{"issue":"1-2","key":"10.1053\/j.ajkd.2012.08.035_bib14","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/0022-510X(95)00226-7","article-title":"Brain MRI findings and cognitive impairment in patients undergoing chronic hemodialysis treatment","volume":"134","author":"Fazekas","year":"1995","journal-title":"J Neurol Sci"},{"issue":"3","key":"10.1053\/j.ajkd.2012.08.035_bib15","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1385\/JMN:20:3:241","article-title":"Hippocampal volume is associated with memory but not nonmemory cognitive performance in patients with mild cognitive impairment","volume":"20","author":"Grundman","year":"2003","journal-title":"J Mol Neurosci"},{"issue":"13","key":"10.1053\/j.ajkd.2012.08.035_bib16","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1056\/NEJMoa022066","article-title":"Silent brain infarcts and the risk of dementia and cognitive decline","volume":"348","author":"Vermeer","year":"2003","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1053\/j.ajkd.2012.08.035_bib17","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1525-139X.2011.00857.x","article-title":"Does hemodialysis hurt the brain?","volume":"24","author":"Madero","year":"2011","journal-title":"Semin Dial"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib18","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1212\/01.wnl.0000225182.15532.40","article-title":"Cognitive impairment in hemodialysis patients is common","volume":"67","author":"Murray","year":"2006","journal-title":"Neurology"},{"issue":"3","key":"10.1053\/j.ajkd.2012.08.035_bib19","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/j.1542-4758.2007.00185.x","article-title":"Subcortical cognitive impairment in dialysis patients","volume":"11","author":"Pereira","year":"2007","journal-title":"Hemodial Int"},{"issue":"5","key":"10.1053\/j.ajkd.2012.08.035_bib20","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1053\/j.ajkd.2011.03.034","article-title":"Cardiovascular disease and cognitive function in maintenance hemodialysis patients","volume":"58","author":"Weiner","year":"2011","journal-title":"Am J Kidney Dis"},{"issue":"11","key":"10.1053\/j.ajkd.2012.08.035_bib21","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.2337\/dc11-0969","article-title":"Adhesion molecules, altered vasoreactivity, and brain atrophy in type 2 diabetes","volume":"34","author":"Novak","year":"2011","journal-title":"Diabetes Care"},{"issue":"5","key":"10.1053\/j.ajkd.2012.08.035_bib22","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1161\/HYPERTENSIONAHA.110.160002","article-title":"Hypertension and cerebral vasoreactivity","volume":"56","author":"Hajjar","year":"2010","journal-title":"Hypertension"},{"issue":"4","key":"10.1053\/j.ajkd.2012.08.035_bib23","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1053\/j.ajkd.2010.02.337","article-title":"Estimating GFR using the CKD Epidemiology Collaboration (CKD-EPI) creatinine equation: more accurate GFR estimates, lower CKD prevalence estimates, and better risk predictions","volume":"55","author":"Levey","year":"2010","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"10.1053\/j.ajkd.2012.08.035_bib24","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1148\/radiology.202.1.8988189","article-title":"Sulcal, ventricular, and white matter changes at MR imaging in the aging brain: data from the Cardiovascular Health Study","volume":"202","author":"Yue","year":"1997","journal-title":"Radiology"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib25","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1161\/01.STR.25.2.318","article-title":"Magnetic resonance abnormalities and cardiovascular disease in older adults","volume":"25","author":"Manolio","year":"1994","journal-title":"Stroke"},{"issue":"1","key":"10.1053\/j.ajkd.2012.08.035_bib26","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1148\/radiology.202.1.8988191","article-title":"Infarctlike lesions in the brain: prevalence and anatomic characteristics at MR imaging of the elderly\u2014data from the Cardiovascular Health Study","volume":"202","author":"Bryan","year":"1997","journal-title":"Radiology"},{"issue":"7","key":"10.1053\/j.ajkd.2012.08.035_bib27","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1212\/WNL.57.7.1222","article-title":"Silent MRI infarcts and the risk of future stroke","volume":"57","author":"Bernick","year":"2001","journal-title":"Neurology"},{"issue":"3","key":"10.1053\/j.ajkd.2012.08.035_bib28","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1148\/radiology.194.3.7862964","article-title":"Cerebral metabolite patterns in dialysis patients: evaluation with H-1 MR spectroscopy","volume":"194","author":"Geissler","year":"1995","journal-title":"Radiology"},{"issue":"1","key":"10.1053\/j.ajkd.2012.08.035_bib29","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1053\/j.ajkd.2007.03.019","article-title":"High prevalence of leukoaraiosis in cerebral magnetic resonance images of patients on peritoneal dialysis","volume":"50","author":"Kim","year":"2007","journal-title":"Am J Kidney Dis"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib30","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000068034","article-title":"Silent cerebral infarction in hemodialysis patients","volume":"23","author":"Nakatani","year":"2003","journal-title":"Am J Nephrol"},{"issue":"12","key":"10.1053\/j.ajkd.2012.08.035_bib31","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1161\/STROKEAHA.107.493593","article-title":"Chronic kidney disease is associated with white matter hyperintensity volume","volume":"38","author":"Khatri","year":"2007","journal-title":"Stroke"},{"issue":"13","key":"10.1053\/j.ajkd.2012.08.035_bib32","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1056\/NEJMoa041031","article-title":"Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization","volume":"351","author":"Go","year":"2004","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1053\/j.ajkd.2012.08.035_bib33","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1046\/j.1523-1755.2003.00109.x","article-title":"Chronic kidney disease, anemia, and incident stroke in a middle-aged, community-based population: the ARIC Study","volume":"64","author":"Abramson","year":"2003","journal-title":"Kidney Int"},{"issue":"6","key":"10.1053\/j.ajkd.2012.08.035_bib34","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1016\/S0272-6386(99)70016-8","article-title":"Hemodialysis causes severe orthostatic reduction in cerebral blood flow velocity in diabetic patients","volume":"34","author":"Ishida","year":"1999","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"10.1053\/j.ajkd.2012.08.035_bib35","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jstrokecerebrovasdis.2006.08.004","article-title":"Cerebral microbleeds and intracerebral hemorrhages in patients on maintenance hemodialysis","volume":"16","author":"Watanabe","year":"2007","journal-title":"J Stroke Cerebrovasc Dis"},{"issue":"3","key":"10.1053\/j.ajkd.2012.08.035_bib36","first-page":"439","article-title":"Morphologic cerebral changes in patients undergoing dialysis for renal failure","volume":"4","author":"Kretzschmar","year":"1983","journal-title":"AJNR Am J Neuroradiol"},{"issue":"12","key":"10.1053\/j.ajkd.2012.08.035_bib37","doi-asserted-by":"crossref","first-page":"2528","DOI":"10.1161\/01.STR.28.12.2528","article-title":"Cerebral magnetic resonance T2 high intensities in end-stage renal disease","volume":"28","author":"Suzuki","year":"1997","journal-title":"Stroke"},{"issue":"4","key":"10.1053\/j.ajkd.2012.08.035_bib38","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1681\/ASN.V104891","article-title":"Hyperhomocysteinemia in chronic renal disease","volume":"10","author":"Bostom","year":"1999","journal-title":"J Am Soc Nephrol"},{"issue":"7","key":"10.1053\/j.ajkd.2012.08.035_bib39","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1093\/ndt\/15.7.1014","article-title":"Arterial stiffening and vascular calcifications in end-stage renal disease","volume":"15","author":"Gu\u00e9rin","year":"2000","journal-title":"Nephrol Dial Transplant"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638612011778?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638612011778?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T02:04:10Z","timestamp":1759457050000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638612011778"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,2]]}},"alternative-id":["S0272638612011778"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2012.08.035","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anatomic Brain Disease in Hemodialysis Patients: A Cross-sectional Study","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2012.08.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}