{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:05:53Z","timestamp":1792019153665,"version":"4.4.0"},"reference-count":53,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T00:00:00Z","timestamp":1435708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["ajkd.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Kidney Diseases"],"published-print":{"date-parts":[[2015,7]]},"DOI":"10.1053\/j.ajkd.2015.01.019","type":"journal-article","created":{"date-parts":[[2015,3,22]],"date-time":"2015-03-22T15:04:42Z","timestamp":1427036682000},"page":"114-124","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":167,"title":["A Prospective Controlled Study of Living Kidney Donors: Three-Year Follow-up"],"prefix":"10.1053","volume":"66","author":[{"given":"Bertram L.","family":"Kasiske","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Anderson-Haag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay K.","family":"Israni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto S.","family":"Kalil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul L.","family":"Kimmel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward S.","family":"Kraus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew A.","family":"Posselt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd E.","family":"Pesavento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Rabb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"Steffes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon J.","family":"Snyder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Weir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9731","key":"10.1053\/j.ajkd.2015.01.019_bib1","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1016\/S0140-6736(10)60674-5","article-title":"Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis","volume":"375","author":"Matsushita","year":"2010","journal-title":"Lancet"},{"issue":"1","key":"10.1053\/j.ajkd.2015.01.019_bib2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1038\/ki.2010.531","article-title":"Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts","volume":"80","author":"Gansevoort","year":"2011","journal-title":"Kidney Int"},{"issue":"10","key":"10.1053\/j.ajkd.2015.01.019_bib3","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1038\/sj.ki.5001819","article-title":"Proteinuria and reduced kidney function in living kidney donors: a systematic review, meta-analysis, and meta-regression","volume":"70","author":"Garg","year":"2006","journal-title":"Kidney Int"},{"issue":"3","key":"10.1053\/j.ajkd.2015.01.019_bib4","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1053\/j.ajkd.2013.01.027","article-title":"A\u00a0prospective controlled study of kidney donors: baseline and 6-month follow-up","volume":"62","author":"Kasiske","year":"2013","journal-title":"Am J Kidney Dis"},{"issue":"9","key":"10.1053\/j.ajkd.2015.01.019_bib5","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"A\u00a0new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"issue":"1","key":"10.1053\/j.ajkd.2015.01.019_bib6","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1056\/NEJMoa1114248","article-title":"Estimating glomerular filtration rate from serum creatinine and cystatin C","volume":"367","author":"Inker","year":"2012","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1053\/j.ajkd.2015.01.019_bib7","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.annepidem.2011.10.010","article-title":"Prescription medication use among normal weight, overweight, and obese adults, United States, 2005-2008","volume":"22","author":"Kit","year":"2012","journal-title":"Ann Epidemiol"},{"issue":"8","key":"10.1053\/j.ajkd.2015.01.019_bib8","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1093\/ndt\/12.8.1615","article-title":"Long-term follow-up of kidney donors: a longitudinal study","volume":"12","author":"Saran","year":"1997","journal-title":"Nephrol Dial Transplant"},{"issue":"4","key":"10.1053\/j.ajkd.2015.01.019_bib9","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1097\/TP.0b013e318240e9b9","article-title":"Effects of preexistent hypertension on blood pressure and residual renal function after donor nephrectomy","volume":"93","author":"Tent","year":"2012","journal-title":"Transplantation"},{"key":"10.1053\/j.ajkd.2015.01.019_bib10","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/geronj\/31.2.155","article-title":"The effect of age on creatinine clearance in men: a cross-sectional and longitudinal study","volume":"31","author":"Rowe","year":"1976","journal-title":"J\u00a0Gerontol"},{"issue":"4","key":"10.1053\/j.ajkd.2015.01.019_bib11","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1111\/j.1532-5415.1985.tb07117.x","article-title":"Longitudinal studies on the rate of decline in renal function with age","volume":"33","author":"Lindeman","year":"1985","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"3","key":"10.1053\/j.ajkd.2015.01.019_bib12","doi-asserted-by":"crossref","first-page":"185","DOI":"10.7326\/0003-4819-145-3-200608010-00006","article-title":"Meta-analysis: risk for hypertension in living kidney donors","volume":"145","author":"Boudville","year":"2006","journal-title":"Ann Intern Med"},{"issue":"3","key":"10.1053\/j.ajkd.2015.01.019_bib13","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/TP.0b013e31817ba9e3","article-title":"Cardiovascular disease and hypertension risk in living kidney donors: an analysis of health administrative data in Ontario, Canada","volume":"86","author":"Garg","year":"2008","journal-title":"Transplantation"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib14","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1056\/NEJMoa0804883","article-title":"Long-term consequences of kidney donation","volume":"360","author":"Ibrahim","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"1","key":"10.1053\/j.ajkd.2015.01.019_bib15","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1111\/j.1600-6143.2012.04303.x","article-title":"Medical outcomes in African American live kidney donors: a matched cohort study","volume":"13","author":"Doshi","year":"2013","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1053\/j.ajkd.2015.01.019_bib16","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1056\/NEJMoa1000950","article-title":"Racial variation in medical outcomes among living kidney donors","volume":"363","author":"Lentine","year":"2010","journal-title":"N\u00a0Engl J Med"},{"issue":"5, pt 1","key":"10.1053\/j.ajkd.2015.01.019_bib17","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1399-0012.1997.tb00844.x","article-title":"Assessment of long-term risks for living related kidney donors by 24-h blood pressure monitoring and testing for microalbuminuria","volume":"11","author":"Eberhard","year":"1997","journal-title":"Clin Transplant"},{"issue":"12","key":"10.1053\/j.ajkd.2015.01.019_bib18","doi-asserted-by":"crossref","first-page":"2648","DOI":"10.1093\/ndt\/gfg482","article-title":"Risks and complications in 160 living kidney donors who underwent nephroureterectomy","volume":"18","author":"Siebels","year":"2003","journal-title":"Nephrol Dial Transplant"},{"issue":"2","key":"10.1053\/j.ajkd.2015.01.019_bib19","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/01.TP.0000128168.97735.B3","article-title":"Blood pressure and renal function after kidney donation from hypertensive living donors","volume":"78","author":"Textor","year":"2004","journal-title":"Transplantation"},{"issue":"4","key":"10.1053\/j.ajkd.2015.01.019_bib20","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1291\/hypres.28.301","article-title":"Circadian blood pressure rhythm is disturbed by nephrectomy","volume":"28","author":"Goto","year":"2005","journal-title":"Hypertens Res"},{"issue":"9","key":"10.1053\/j.ajkd.2015.01.019_bib21","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1097\/TP.0b013e318188425b","article-title":"A\u00a0prospective observational study of changes in renal function and cardiovascular risk following living kidney donation","volume":"86","author":"Prasad","year":"2008","journal-title":"Transplantation"},{"issue":"8","key":"10.1053\/j.ajkd.2015.01.019_bib22","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1111\/j.1432-2277.2009.01040.x","article-title":"Twenty four-hour ambulatory blood pressure profiles 12 months post living kidney donation","volume":"23","author":"Ramesh Prasad","year":"2010","journal-title":"Transpl Int"},{"issue":"6","key":"10.1053\/j.ajkd.2015.01.019_bib23","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1291\/hypres.24.691","article-title":"Significance of hyperuricemia on the early detection of renal failure in a cohort of screened subjects","volume":"24","author":"Iseki","year":"2001","journal-title":"Hypertens Res"},{"issue":"4","key":"10.1053\/j.ajkd.2015.01.019_bib24","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1093\/ndt\/gfm790","article-title":"Predictors of new-onset decline in kidney function in a general middle-european population","volume":"23","author":"Obermayr","year":"2008","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"10.1053\/j.ajkd.2015.01.019_bib25","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1681\/ASN.2007101075","article-title":"Uric acid and incident kidney disease in the community","volume":"19","author":"Weiner","year":"2008","journal-title":"J\u00a0Am Soc Nephrol"},{"issue":"4","key":"10.1053\/j.ajkd.2015.01.019_bib26","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1001\/archinternmed.2008.605","article-title":"Risk factors for end-stage renal disease: 25-year follow-up","volume":"169","author":"Hsu","year":"2009","journal-title":"Arch Intern Med"},{"issue":"8","key":"10.1053\/j.ajkd.2015.01.019_bib27","doi-asserted-by":"crossref","first-page":"2558","DOI":"10.1093\/ndt\/gfq740","article-title":"Serum uric acid is a GFR-independent long-term predictor of acute and chronic renal insufficiency: the Jerusalem Lipid Research Clinic cohort study","volume":"26","author":"Ben-Dov","year":"2011","journal-title":"Nephrol Dial Transplant"},{"issue":"1","key":"10.1053\/j.ajkd.2015.01.019_bib28","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1002\/acr.20344","article-title":"Hyperuricemia and incident hypertension: a systematic review and meta-analysis","volume":"63","author":"Grayson","year":"2011","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"9","key":"10.1053\/j.ajkd.2015.01.019_bib29","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.2337\/dc09-0288","article-title":"Association between serum uric acid and development of type 2 diabetes","volume":"32","author":"Kodama","year":"2009","journal-title":"Diabetes Care"},{"issue":"7","key":"10.1053\/j.ajkd.2015.01.019_bib30","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1002\/art.24612","article-title":"Hyperuricemia and risk of stroke: a systematic review and meta-analysis","volume":"61","author":"Kim","year":"2009","journal-title":"Arthritis Rheum"},{"issue":"2","key":"10.1053\/j.ajkd.2015.01.019_bib31","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1002\/acr.20065","article-title":"Hyperuricemia and coronary heart disease: a systematic review and meta-analysis","volume":"62","author":"Kim","year":"2010","journal-title":"Arthritis Care Res (Hoboken)"},{"issue":"17","key":"10.1053\/j.ajkd.2015.01.019_bib32","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1056\/NEJMra0800885","article-title":"Uric acid and cardiovascular risk","volume":"359","author":"Feig","year":"2008","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib33","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/01.tp.0000436906.48802.c4","article-title":"Uremic toxin development in living kidney donors: a longitudinal study","volume":"97","author":"Rossi","year":"2014","journal-title":"Transplantation"},{"issue":"3","key":"10.1053\/j.ajkd.2015.01.019_bib34","doi-asserted-by":"crossref","first-page":"c82","DOI":"10.1159\/000108648","article-title":"Do biochemical measures change in living kidney donors? A systematic review","volume":"107","author":"Young","year":"2007","journal-title":"Nephron Clin Pract"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib35","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1016\/S0041-1345(98)00622-8","article-title":"Long-term follow-up of renal donors","volume":"30","author":"Undurraga","year":"1998","journal-title":"Transplant Proc"},{"issue":"4","key":"10.1053\/j.ajkd.2015.01.019_bib36","first-page":"511","article-title":"Renal function after nephrectomy in renal donors","volume":"7","author":"Hida","year":"1982","journal-title":"Tokai J Exp Clin Med"},{"issue":"2","key":"10.1053\/j.ajkd.2015.01.019_bib37","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1097\/00007890-200007270-00027","article-title":"Serum erythropoietin levels in kidney donors after renal transplantation","volume":"70","author":"Romero","year":"2000","journal-title":"Transplantation"},{"issue":"3","key":"10.1053\/j.ajkd.2015.01.019_bib38","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1159\/000188471","article-title":"The prevalence of insulin resistance in kidney disease patients before the development of renal failure","volume":"69","author":"Dzurik","year":"1995","journal-title":"Nephron"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib39","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/BF00400725","article-title":"Insulin resistance and hyperinsulinaemia in mild to moderate progressive chronic renal failure and its association with aerobic work capacity","volume":"38","author":"Eidemak","year":"1995","journal-title":"Diabetologia"},{"issue":"2","key":"10.1053\/j.ajkd.2015.01.019_bib40","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/ki.1997.360","article-title":"Insulin resistance in adult polycystic kidney disease","volume":"52","author":"Vareesangthip","year":"1997","journal-title":"Kidney Int"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib41","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1046\/j.1523-1755.1998.00898.x","article-title":"Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease","volume":"53","author":"Fliser","year":"1998","journal-title":"Kidney Int"},{"issue":"6","key":"10.1053\/j.ajkd.2015.01.019_bib42","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1046\/j.1523-1755.1999.00458.x","article-title":"Effect of hyperinsulinemia on renal function in a general Japanese population: the Hisayama study","volume":"55","author":"Kubo","year":"1999","journal-title":"Kidney Int"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib43","first-page":"366","article-title":"Mild renal dysfunction is associated with insulin resistance in chronic glomerulonephritis","volume":"54","author":"Kato","year":"2000","journal-title":"Clin Nephrol"},{"issue":"6","key":"10.1053\/j.ajkd.2015.01.019_bib44","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.lab.2004.03.001","article-title":"Plasma homocysteine levels in living kidney donors before and after uninephrectomy","volume":"143","author":"Tsai","year":"2004","journal-title":"J\u00a0Lab Clin Med"},{"issue":"18","key":"10.1053\/j.ajkd.2015.01.019_bib45","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1001\/archinternmed.2010.348","article-title":"Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: meta-analysis of 8 randomized trials involving 37 485 individuals","volume":"170","author":"Clarke","year":"2010","journal-title":"Arch Intern Med"},{"key":"10.1053\/j.ajkd.2015.01.019_bib46","doi-asserted-by":"crossref","first-page":"e3533","DOI":"10.1136\/bmj.e3533","article-title":"The effect of folic acid based homocysteine lowering on cardiovascular events in people with kidney disease: systematic review and meta-analysis","volume":"344","author":"Jardine","year":"2012","journal-title":"BMJ"},{"issue":"3","key":"10.1053\/j.ajkd.2015.01.019_bib47","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1038\/ki.1975.96","article-title":"Renal function before and after unilateral nephrectomy in renal donors","volume":"8","author":"Pabico","year":"1975","journal-title":"Kidney Int"},{"issue":"5","key":"10.1053\/j.ajkd.2015.01.019_bib48","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0272-6386(88)80052-0","article-title":"The effect of uninephrectomy on mineral metabolism in normal human kidney donors","volume":"11","author":"Friedlander","year":"1988","journal-title":"Am J Kidney Dis"},{"issue":"1","key":"10.1053\/j.ajkd.2015.01.019_bib49","first-page":"1946","article-title":"Long-term renal, endocrine, and hematologic evaluation of kidney donors","volume":"21","author":"Gonzalez","year":"1989","journal-title":"Transplant Proc"},{"issue":"10","key":"10.1053\/j.ajkd.2015.01.019_bib50","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1111\/j.1600-6143.2005.01037.x","article-title":"Long-term consequences of live kidney donation follow-up in 93% of living kidney donors in a single transplant center","volume":"5","author":"Gossmann","year":"2005","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1053\/j.ajkd.2015.01.019_bib51","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1016\/j.transproceed.2009.09.039","article-title":"Serum\u00a0concentration of vitamin D and parathyroid hormone after\u00a0living kidney donation","volume":"41","author":"Bieniasz","year":"2009","journal-title":"Transplant Proc"},{"issue":"12","key":"10.1053\/j.ajkd.2015.01.019_bib52","doi-asserted-by":"crossref","first-page":"4068","DOI":"10.1093\/ndt\/gfq288","article-title":"Fibroblast growth factor-23 and mineral metabolism after unilateral nephrectomy","volume":"25","author":"Westerberg","year":"2010","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"10.1053\/j.ajkd.2015.01.019_bib53","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1053\/j.ajkd.2011.09.019","article-title":"Bone and mineral metabolism and fibroblast growth factor 23 levels after kidney donation","volume":"59","author":"Young","year":"2012","journal-title":"Am J Kidney Dis"}],"container-title":["American Journal of Kidney Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638615004862?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0272638615004862?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T02:32:17Z","timestamp":1759458737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0272638615004862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["S0272638615004862"],"URL":"https:\/\/doi.org\/10.1053\/j.ajkd.2015.01.019","relation":{},"ISSN":["0272-6386"],"issn-type":[{"value":"0272-6386","type":"print"}],"subject":[],"published":{"date-parts":[[2015,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Prospective Controlled Study of Living Kidney Donors: Three-Year Follow-up","name":"articletitle","label":"Article Title"},{"value":"American Journal of Kidney Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1053\/j.ajkd.2015.01.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}